
Butler County Vacations & Trips from $695
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Your Butler County Vacation
Answer the call of adventure with a customized vacation package to Butler County. Wherever it is you're headed and whatever you have planned, get ready to immerse yourself in a destination that'll make you truly feel alive. A trip to Butler County offers lots of things to see and do. Not sure where to begin? Poplar Bluff is one of the most popular cities to stay here. From the instant you book your Butler County vacation to when you get back home, Expedia has you covered every step of the way.
Top destinations in Butler County

Poplar Bluff
The Latest Butler County Vacation Packages
Price found within the past 48 hours. Click for updated prices.

University Inn of Carbondale by Hotel O
$695
per person
Oct 22 - Oct 25
found 15 hours ago
Roundtrip non-stop flight included
Syracuse (SYR) to Cape Girardeau (CGI)
5.8/10 (402 reviews)
i made this reservation but when I got there that night at about 7 pm they said that they did not have a room for me
Reviewed on Aug 27, 2026

Makanda Inn
$1,196
per person
Oct 22 - Oct 25
found 15 hours ago
Roundtrip non-stop flight included
Syracuse (SYR) to Cape Girardeau (CGI)
10/10 Exceptional! (39 reviews)
I travel to So. Illinois annually to visit but this is my first stay at the Makanda Inn. It will not be my last. I had a very peaceful stay- after long days of family visit and running around with the grands, it was so nice to stay here where it was quiet and relaxing. Breakfast every morning was top notch and just the right portions.
Reviewed on Jul 22, 2026



Drury Plaza Hotel Cape Girardeau Conference Center
$801
per person
Oct 29 - Nov 1
found 16 hours ago
Roundtrip non-stop flight included
Philadelphia (PHL) to Cape Girardeau (CGI)
9.6/10 Exceptional! (1,011 reviews)
Competitively priced. Complimentary happy hour and hot breakfast were exceptional. We stay at a Drury Inn whenever they are available.
Reviewed on Aug 27, 2026
Find the Best Butler County Vacation Packages
Butler County Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Lambert-St. Louis Intl. Airport (STL) |
Butler County Hotel Deals

Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$79 nightly
$88 total
Aug 30 - Aug 31
Total with taxes and fees
8/10 Very Good! (1,000 reviews)
"The floors were sticky. I couldn't walk on them in my bare feet. I did but then had to wash them."
Reviewed on Aug 25, 2026

Fairfield Inn & Suites by Marriott Poplar Bluff
3109 Oak Grove Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$101 nightly
$114 total
Sep 7 - Sep 8
Total with taxes and fees
9.4/10 Exceptional! (957 reviews)
"loved it!!!"
Reviewed on Aug 25, 2026

Drury Inn & Suites Poplar Bluff
2220 N Westwood Blvd Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$102 nightly
$115 total
Sep 6 - Sep 7
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Butler County attractions
Black River Coliseum
8.2/10 (30 reviews)
Catch an event at Black River Coliseum during your trip to Poplar Bluff. While in this family-friendly area, you can enjoy the restaurants.
Mo-Ark Regional Railroad Museum
6.8/10 (13 reviews)
You can study the exhibits at Mo-Ark Regional Railroad Museum, a museum with a storied past, during your travels to Poplar Bluff. While in this family-friendly area, you can enjoy the restaurants.
North Main Street Historic District
You can find out about the history of Poplar Bluff with a trip to North Main Street Historic District. While in this family-friendly area, you can enjoy the restaurants.
Redman Creek Recreation Area
Explore the great outdoors at Redman Creek Recreation Area, a lovely green space in Wappapello.
Margaret Harwell Art Museum
5.8/10 (8 reviews)
You can study the exhibits at Margaret Harwell Art Museum, a museum with a storied past, during your travels to Poplar Bluff. Stroll along the riverfront or experience the entertainment venues in this family-friendly area.
Ozark Ridge Golf Course
7.4/10 (3 reviews)
Enjoy a round of golf in Poplar Bluff at Ozark Ridge Golf Course. Take in the entertainment venues and waterfalls in the area.
Rockwood Point Recreation Area
Explore the great outdoors at Rockwood Point Recreation Area, a lovely green space in Wappapello.
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