Downtown San Mateo Vacations from $347

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Your Downtown San Mateo Vacation

A well-liked commercial neighborhood, Downtown San Mateo lures travelers with its shopping, history and nature. Book a vacation package to Downtown San Mateo and discover all of those highlights and more. Start your trip to Downtown San Mateo by heading to nearby attractions such as Coyote Point Park, Hillsdale Shopping Center and Poplar Creek Golf Course. Expedia can put your plans into action. Book your perfect Downtown San Mateo vacation today.

The Latest Downtown San Mateo Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Fitzgerald Hotel

Fitzgerald Hotel

3 out of 5
Union Square
Price was $810, price is now $347 per person
$347
per person
Dec 25 - Dec 31
found 14 hours ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
7.8/10 Good! (447 reviews)
The hotel is easy access to all tourist spots

Reviewed on Oct 6, 2025

1 Hotel San Francisco

1 Hotel San Francisco

5 out of 5
Downtown San Francisco
Save 100% on your flight
Price was $1,346, price is now $757 per person
$757
per person
Jan 4 - Jan 7
found 10 hours ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
9.2/10 Wonderful! (450 reviews)
Great location and property

Reviewed on Oct 7, 2025

Marbella Lane Tuscan Villa with Hot Tub

Marbella Lane Tuscan Villa with Hot Tub

3 out of 5
Rockaway Beach
Price was $4,361, price is now $2,518 per person
$2,518
per person
Dec 26 - Dec 30
found 16 hours ago
Roundtrip flight included
Los Angeles (LAX) to San Francisco (SFO)
9.6/10 Exceptional! (17 reviews)
DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina

4 out of 5
Save 100% on your flight
Price was $1,116, price is now $649 per person
$649
per person
Nov 22 - Nov 29
found 20 hours ago
Roundtrip non-stop flight included
Dallas (DFW) to Oakland (OAK)
8.2/10 Very Good! (3,424 reviews)
They did not honor a request for a room in building one of two. I actually called the desk a day prior to check in. When I checked at the front they told me I should have written down the name of the person I spoke with since It was not written in their records.

Reviewed on Oct 13, 2025

Nob Hill Hotel

Nob Hill Hotel

4 out of 5
Downtown San Francisco
Save 100% on your flight
Price was $994, price is now $584 per person
$584
per person
Dec 25 - Dec 31
found 14 hours ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
7.8/10 Good! (1,003 reviews)
Great clean room, comfy bed, windows open for fresh air. Also there is a ceiling fan. I love staying here.

Reviewed on Oct 14, 2025

Where to stay in Downtown San Mateo

Find the best Downtown San Mateo areas and neighborhoods for the activities you enjoy most. Learn more about Downtown San Mateo
Union Square which includes a high rise building and a city

Union Square

4/5(5,164 area reviews)

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Find hotels in Union Square

Downtown San Mateo Hotel Deals

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave, San Francisco, CA
Fully refundableReserve now, pay when you stay
$124 nightly
The price is $146 total per night from Nov 9 to Nov 10
$146 total
Nov 9 - Nov 10
Total with taxes and fees
8.8/10 Excellent! (4,681 reviews)
"The room was cleaned well. Parking was a plus. We enjoyed our stay. The hotel was close to Pier 39. We felt safe too."

Reviewed on Oct 11, 2025

Holiday Inn Golden Gateway by IHG
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$124 nightly
The price is $146 total per night from Nov 9 to Nov 10
$146 total
Nov 9 - Nov 10
Total with taxes and fees
8.6/10 Excellent! (1,881 reviews)
"Very pretty view day and night and very clean"

Reviewed on Oct 13, 2025

Hilton San Francisco Financial District
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$153 nightly
The price is $180 total per night from Oct 17 to Oct 18
$180 total
Oct 17 - Oct 18
Total with taxes and fees
8.8/10 Excellent! (6,994 reviews)
No coffee to go
"I didn’t want breakfast I was just wanting coffee to go and they would not let me get coffee to go. The room was nice though and location is great for Pier 39, Ghirardelli Square, and Fisherman’s Wharf."

Reviewed on Oct 14, 2025

Hotel Riu Plaza Fisherman's Wharf
See all 4,551 properties in Downtown San Mateo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Downtown San Mateo

Central Park

Central Park is just one of the places to see in San Mateo, so why not enjoy the other things to explore during your travels? Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Central Park

The San Mateo Japanese Garden

Enjoy an outing to The San Mateo Japanese Garden during your stay in San Mateo. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

The San Mateo Japanese Garden

Things to do

Filoli House & Garden

Filoli House & Garden

$34
per adult
100% of travellers recommend
Filoli House & Garden
The Golden Hour

2hr. SUNSET Sailing Experience on San Francisco Bay

$149
per adult
2hr. SUNSET Sailing Experience on San Francisco Bay
Inglenook and Sut,Napa Valley&Sausalito 1-Day Tou

Napa and Sonoma Small Group Wine Tour from San Francisco

$168
per traveler
Napa and Sonoma Small Group Wine Tour from San Francisco
See all activities in San Francisco
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.