Domene Vacations from $918

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Domene Vacation

With plenty of highlights as well as hidden gems, this city is best experienced with a Domene vacation package. Look for places to stay in Grenoble City Centre, which is great for culture, walking and history. Want to start exploring your surroundings? Museum of Grenoble, Fort de la Bastille and Paul Mistral Park are among the best places to visit during a trip to Domene. Whatever your travel plans or budget, putting together the ultimate tailored Domene vacation is a breeze with Expedia.

The Latest Domene vacation packages

Price found within the past 48 hours. Click for updated prices.
Carlton Hotel Lyon - MGallery Collection

Carlton Hotel Lyon - MGallery Collection

4 out of 5
Lyon City Centre
Price was $1,119, price is now $918 per person
$918
per person
Mar 26 - Mar 31
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Lyon (LYS)
9.4/10 Exceptional! (1,001 reviews)
The room was large and clean. Staff young m Do not go to bar or room service. Not worth price and horrible service in bar and room service was crazy price for cold coffee and tea

Reviewed on Jan 22, 2026

Hôtel Maison Lacassagne

Hôtel Maison Lacassagne

4 out of 5
3rd Arrondissement
Price was $1,195, price is now $930 per person
$930
per person
Mar 23 - Mar 27
found 24 hours ago
Roundtrip non-stop flight included
New York (NYC) to Lyon (LYS)
9.2/10 Wonderful! (135 reviews)
Thank you for this wonderful stay and lovely team !

Reviewed on Apr 7, 2025

Globe et Cecil Hôtel

Globe et Cecil Hôtel

4 out of 5
Lyon City Centre
Price was $1,510, price is now $1,181 per person
$1,181
per person
Mar 26 - Mar 31
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Lyon (LYS)
8.4/10 Very Good! (520 reviews)
Easy and efficinet checking in and out. Helpful and polite staff. Nice and clean room. Small hotel, cosy and with character. Good breakfast. Great location. Will stay again if offers reasonable price.

Reviewed on Feb 8, 2026

Le Royal Hotel Lyon - MGallery Collection

Le Royal Hotel Lyon - MGallery Collection

5 out of 5
Lyon City Centre
Price was $1,192, price is now $958 per person
$958
per person
Mar 26 - Mar 31
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Lyon (LYS)
9/10 Wonderful! (1,000 reviews)
Clean room , very good breakfast, outstanding staff … except for the front desk.Front desk is quite aloof and could not care less.

Reviewed on Dec 28, 2025

Chalet Alpen Valley, Mont-Blanc

Chalet Alpen Valley, Mont-Blanc

4 out of 5
Price was $1,462, price is now $1,189 per person
$1,189
per person
Mar 23 - Mar 27
found 24 hours ago
Roundtrip non-stop flight included
New York (NYC) to Lyon (LYS)
9.8/10 Exceptional! (68 reviews)
Great place to spend a night,we had a room that had a view of Mont Blanc.Staff were exceptionally friendly and I felt they were genuine and they were pleased that we had booked their hotel,was very impressed with the lady that greeted us on arrival and she showed us our room,she made us feel very welcomed and made us feel that we were very important.

Reviewed on Jan 21, 2026

Don't see what you're looking for?
See all available trips from Columbus to Domene
View all trips

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.
Book now

Domene Hotel Deals

OKKO Hotels Grenoble Centre

OKKO Hotels Grenoble Centre

4 out of 5
23 rue Hoche Grenoble Isere
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $106 total per night from Mar 6 to Mar 7
$106 total
Mar 6 - Mar 7
Total with taxes and fees
9/10 Wonderful! (1,000 reviews)
The staff are friendly, helpfuo and professional. Club room is a great advantage and a lovrpy relaxing social space. Rooms are design led, compact but all the features you need, temperature, bed and light all great!

Reviewed on Feb 1, 2026

OKKO Hotels Grenoble Centre
PoMo Hotel & Restaurant

PoMo Hotel & Restaurant

4 out of 5
16 Avenue De Kimberley Echirolles Isere
Fully refundableReserve now, pay when you stay
8.8/10 Excellent! (553 reviews)
The room was clean, we travelled in adverse weather phoned a head to advise we were going to be late. The guy we spoke to on the phone was absolutely brilliant, he spoke very good english and when we arrived he was so accimadating

Reviewed on Jan 30, 2026

Get rates
PoMo Hotel & Restaurant
Residhotel Grenette

Residhotel Grenette

3 out of 5
12 rue de Palanka Grenoble Isere
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $64 total per night from Mar 15 to Mar 16
$64 total
Mar 15 - Mar 16
Total with taxes and fees
8.2/10 Very Good! (1,129 reviews)
Central location, quiet location, clean room

Reviewed on Feb 6, 2026

Residhotel Grenette
See all 6,703 properties in Domene
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Domene Vacation Packages

Domene Essential Information

Language
French
Currency
Euros
Local Welcome
Salut / Bonjour
Local Goodbye
Au revoir / À bientôt
Population
6,900
Max Temp Winter
40ºF
Max Temp Summer
70ºF
Top Sights
Grenoble-Bastille Cable Car, Museum of Grenoble and Museum of Resistance and Deportation

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Domene vacation package cost?
Offering great value package deals from $918 on Expedia, you'll be pleasantly surprised at how much a vacation to Domene costs! Expedia's packages make travel planning easier and save you more.
What are the cheapest months to go to Domene?
November, December and January are great times to search for cheap Domene vacation packages. Choosing to travel in quieter periods means you'll typically find reduced prices on hotels and flights.
How many days is enough for Domene?
With a well-planned itinerary, you can easily visit the top Domene attractions in a few days. But if you want to explore off the beaten track or take day trips, think about booking your Domene vacation for longer.
How to find the best Domene package deals?
Landing a cheap Domene package deal is a cinch with Expedia. After you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, apply some filters and browse what's available. You can fine-tune your search by "Popular locations," "Property type," "Guest rating" and more. Order the results by "Price: low to high" to discover the most affordable Domene package deals. Want a simple trick to get even more savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are typically lower.
Is it cheaper to book a Domene vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to arranging hotels and flights individually. Better still, you can personalize your Domene escape to match your exact style. Pick your preferred flight time, select the hotel type and add a rental car. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Domene?
Enjoy incredible bargains by reserving your flights ahead of time with Expedia. If being spontaneous is more your style, grab one of our last-minute deals for an impromptu Domene trip.
Does Expedia offer Book Now, Pay Later Domene vacation packages?
If you're anything like us, you love traveling but don't love the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With help from online lender Affirm, you can spread the total cost of your Domene trip over 3, 6 or 12 months. There are also no hidden or late payment fees, so you can snap up cheap vacation packages with payment plans as soon as you see them.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.