Domene Vacations from $611

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Your Domene Vacation

With plenty of highlights as well as hidden gems, this city is best experienced with a Domene vacation package. Look for places to stay in Grenoble City Centre, which is great for culture, walking and history. Want to start exploring your surroundings? Museum of Grenoble, Fort de la Bastille and Paul Mistral Park are among the best places to visit during a trip to Domene. Whatever your travel plans or budget, putting together the ultimate tailored Domene vacation is a breeze with Expedia.

The Latest Domene vacation packages

Price found within the past 48 hours. Click for updated prices.
Hôtel Edmond W

Hôtel Edmond W

3 out of 5
Lyon City Centre
Price was $794, price is now $611 per person
$611
per person
Apr 6 - Apr 13
found 18 hours ago
Roundtrip non-stop flight included
Alicante (ALC) to Lyon (LYS)
9/10 Wonderful! (182 reviews)
This is a very charming hotel. We enjoyed our stay. The Massena train stop was a short walk from the hotel, making it convenient to hop on the metro to get to Old Lyon in 10-15 minutes. The staff was very friendly and helpful. Lots of dining options nearby. We would stay here again.

Reviewed on May 31, 2025

Mercure Lyon Centre Saxe Lafayette

Mercure Lyon Centre Saxe Lafayette

4 out of 5
Lyon City Centre
Price was $828, price is now $640 per person
$640
per person
Apr 6 - Apr 13
found 18 hours ago
Roundtrip non-stop flight included
Alicante (ALC) to Lyon (LYS)
8.8/10 Excellent! (1,002 reviews)
Nice workout facility with dipping pool.

Reviewed on Nov 15, 2025

Carlton Hotel Lyon - MGallery Collection

Carlton Hotel Lyon - MGallery Collection

4 out of 5
Lyon City Centre
Save 100% on your flight
Price was $1,072, price is now $833 per person
$833
per person
Apr 6 - Apr 13
found 18 hours ago
Roundtrip non-stop flight included
Alicante (ALC) to Lyon (LYS)
9.4/10 Exceptional! (1,001 reviews)
This is a well located hotel with easy access to great shops and the beautiful old town. All staff were friendly and helpful and in particular the breakfast staff were so positive and helpful as they served the most delicious breakfast.

Reviewed on Feb 20, 2026

Le Royal Hotel Lyon - MGallery Collection

Le Royal Hotel Lyon - MGallery Collection

5 out of 5
Lyon City Centre
Save 100% on your flight
Price was $1,030, price is now $803 per person
$803
per person
Apr 6 - Apr 13
found 18 hours ago
Roundtrip non-stop flight included
Alicante (ALC) to Lyon (LYS)
9/10 Wonderful! (1,000 reviews)
Clean room , very good breakfast, outstanding staff … except for the front desk.Front desk is quite aloof and could not care less.

Reviewed on Dec 28, 2025

Sofitel Lyon Bellecour

Sofitel Lyon Bellecour

5 out of 5
Lyon City Centre
Save 100% on your flight
Price was $1,014, price is now $792 per person
$792
per person
Apr 6 - Apr 13
found 18 hours ago
Roundtrip non-stop flight included
Alicante (ALC) to Lyon (LYS)
8.6/10 Excellent! (1,000 reviews)
Great full-service hotel in an outstanding location. Every staff person showed complete dedication to making my stay pleasant. Morning breakfast with view of the river was memorable. Facilities are not particularly new, but everything in the room was spotless and worked perfectly.

Reviewed on Feb 9, 2026

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Domene Hotel Deals

OKKO Hotels Grenoble Centre

OKKO Hotels Grenoble Centre

4 out of 5
23 rue Hoche Grenoble Isere
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $105 total per night from Mar 6 to Mar 7
$105 total
Mar 6 - Mar 7
Total with taxes and fees
9/10 Wonderful! (1,001 reviews)
The staff are friendly, helpfuo and professional. Club room is a great advantage and a lovrpy relaxing social space. Rooms are design led, compact but all the features you need, temperature, bed and light all great!

Reviewed on Feb 1, 2026

OKKO Hotels Grenoble Centre
PoMo Hotel & Restaurant

PoMo Hotel & Restaurant

4 out of 5
16 Avenue De Kimberley Echirolles Isere
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $126 total per night from Feb 26 to Feb 27
$126 total
Feb 26 - Feb 27
Total with taxes and fees
8.8/10 Excellent! (554 reviews)
Super Nous adorons

Reviewed on Feb 20, 2026

PoMo Hotel & Restaurant
Residhotel Grenette

Residhotel Grenette

3 out of 5
12 rue de Palanka Grenoble Isere
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $64 total per night from Mar 22 to Mar 23
$64 total
Mar 22 - Mar 23
Total with taxes and fees
8.2/10 Very Good! (1,130 reviews)
Central location, quiet location, clean room

Reviewed on Feb 6, 2026

Residhotel Grenette
See all 6,722 properties in Domene
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Domene Vacation Packages

Domene Essential Information

Language
French
Currency
Euros
Local Welcome
Salut / Bonjour
Local Goodbye
Au revoir / À bientôt
Population
6,900
Max Temp Winter
40ºF
Max Temp Summer
70ºF
Top Sights
Grenoble-Bastille Cable Car, Museum of Grenoble and Museum of Resistance and Deportation

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Frequently asked questions

How much does a Domene vacation package cost?
Offering great value package deals from $611 on Expedia, you'll be pleasantly surprised at how much a vacation to Domene costs! Expedia's packages make travel planning easier and save you more.
What are the cheapest months to go to Domene?
November, December and January are great times to search for cheap Domene vacation packages. Choosing to travel in quieter periods means you'll typically find reduced prices on hotels and flights.
How many days is enough for Domene?
With a well-planned itinerary, you can easily visit the top Domene attractions in a few days. But if you want to explore off the beaten track or take day trips, think about booking your Domene vacation for longer.
How to find the best Domene package deals?
Landing a cheap Domene package deal is a cinch with Expedia. After you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, apply some filters and browse what's available. You can fine-tune your search by "Popular locations," "Property type," "Guest rating" and more. Order the results by "Price: low to high" to discover the most affordable Domene package deals. Want a simple trick to get even more savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are typically lower.
Is it cheaper to book a Domene vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to arranging hotels and flights individually. Better still, you can personalize your Domene escape to match your exact style. Pick your preferred flight time, select the hotel type and add a rental car. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Domene?
Enjoy incredible bargains by reserving your flights ahead of time with Expedia. If being spontaneous is more your style, grab one of our last-minute deals for an impromptu Domene trip.
Does Expedia offer Book Now, Pay Later Domene vacation packages?
If you're anything like us, you love traveling but don't love the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With help from online lender Affirm, you can spread the total cost of your Domene trip over 3, 6 or 12 months. There are also no hidden or late payment fees, so you can snap up cheap vacation packages with payment plans as soon as you see them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.