Domene Vacations from $568

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Your Domene Vacation

With plenty of highlights as well as hidden gems, this city is best experienced with a Domene vacation package. Look for places to stay in Grenoble City Centre, which is great for culture, walking and history. Want to start exploring your surroundings? Museum of Grenoble, Fort de la Bastille and Paul Mistral Park are among the best places to visit during a trip to Domene. Whatever your travel plans or budget, putting together the ultimate tailored Domene vacation is a breeze with Expedia.

The Latest Domene vacation packages

Price found within the past 48 hours. Click for updated prices.
Hôtel Edmond W

Hôtel Edmond W

3 out of 5
Lyon City Centre
Save 100% on your flight
Price was $771, price is now $568 per person
$568
per person
Apr 8 - Apr 15
found 1 day ago
Roundtrip flight included
Alicante (ALC) to Lyon (LYS)
9/10 Wonderful! (182 reviews)
This is a very charming hotel. We enjoyed our stay. The Massena train stop was a short walk from the hotel, making it convenient to hop on the metro to get to Old Lyon in 10-15 minutes. The staff was very friendly and helpful. Lots of dining options nearby. We would stay here again.

Reviewed on May 31, 2025

Carlton Hotel Lyon - MGallery Collection

Carlton Hotel Lyon - MGallery Collection

4 out of 5
Lyon City Centre
Save 100% on your flight
Price was $1,328, price is now $924 per person
$924
per person
Apr 8 - Apr 15
found 1 day ago
Roundtrip flight included
Alicante (ALC) to Lyon (LYS)
9.4/10 Exceptional! (1,001 reviews)
The room was large and clean. Staff young m Do not go to bar or room service. Not worth price and horrible service in bar and room service was crazy price for cold coffee and tea

Reviewed on Jan 22, 2026

Hotel Silky by HappyCulture

Hotel Silky by HappyCulture

4 out of 5
Lyon City Centre
Save 100% on your flight
Price was $975, price is now $686 per person
$686
per person
Apr 8 - Apr 15
found 1 day ago
Roundtrip flight included
Alicante (ALC) to Lyon (LYS)
8.8/10 Excellent! (964 reviews)
The staff was lovely and responsive. There were issues with room cleanliness when I arrived (personal items from a previous guest in the bedding). The elevator was under repair for the first couple of days of my trip. The location is very central and the breakfast and refreshments available in the lobby were appreciated. I enjoyed my stay much more once the room was cleaned properly and the elevator was functional. Note: Soundproofing is minimal and noise from other guests and staff can be disruptive.

Reviewed on Feb 8, 2026

The Ruck Hotel

The Ruck Hotel

4 out of 5
7th Arrondissement
Save 100% on your flight
Price was $1,041, price is now $768 per person
$768
per person
Apr 8 - Apr 15
found 1 day ago
Roundtrip flight included
Alicante (ALC) to Lyon (LYS)
9/10 Wonderful! (205 reviews)
Great hotel, very well decorated and spacious.

Reviewed on Feb 18, 2026

Golden Tulip Lyon Ouest Techlid - Hotel and Spa

Golden Tulip Lyon Ouest Techlid - Hotel and Spa

4 out of 5
Save 100% on your flight
Price was $996, price is now $741 per person
$741
per person
Apr 8 - Apr 15
found 1 day ago
Roundtrip flight included
Alicante (ALC) to Lyon (LYS)
9.6/10 Exceptional! (478 reviews)
Didn’t feel like the room was cleaned properly. Many hair in bathrooms and on the robes. Staff wasn’t welcoming nor very pleasant the second night. The restaurant buffet though was very nice high quality foods and nice service. The access to pool and spa opens way too late at 10am and closes way too early at 8pm for people who work…

Reviewed on Dec 3, 2025

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Domene Hotel Deals

OKKO Hotels Grenoble Centre

OKKO Hotels Grenoble Centre

4 out of 5
23 rue Hoche Grenoble Isere
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $106 total per night from Mar 6 to Mar 7
$106 total
Mar 6 - Mar 7
Total with taxes and fees
9/10 Wonderful! (1,001 reviews)
The staff are friendly, helpfuo and professional. Club room is a great advantage and a lovrpy relaxing social space. Rooms are design led, compact but all the features you need, temperature, bed and light all great!

Reviewed on Feb 1, 2026

OKKO Hotels Grenoble Centre
PoMo Hotel & Restaurant

PoMo Hotel & Restaurant

4 out of 5
16 Avenue De Kimberley Echirolles Isere
Fully refundableReserve now, pay when you stay
8.8/10 Excellent! (553 reviews)
The room was clean, we travelled in adverse weather phoned a head to advise we were going to be late. The guy we spoke to on the phone was absolutely brilliant, he spoke very good english and when we arrived he was so accimadating

Reviewed on Jan 30, 2026

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PoMo Hotel & Restaurant
Residhotel Grenette

Residhotel Grenette

3 out of 5
12 rue de Palanka Grenoble Isere
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $64 total per night from Mar 22 to Mar 23
$64 total
Mar 22 - Mar 23
Total with taxes and fees
8.2/10 Very Good! (1,129 reviews)
Central location, quiet location, clean room

Reviewed on Feb 6, 2026

Residhotel Grenette
See all 6,722 properties in Domene
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Domene Vacation Packages

Domene Essential Information

Language
French
Currency
Euros
Local Welcome
Salut / Bonjour
Local Goodbye
Au revoir / À bientôt
Population
6,900
Max Temp Winter
40ºF
Max Temp Summer
70ºF
Top Sights
Grenoble-Bastille Cable Car, Museum of Grenoble and Museum of Resistance and Deportation

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Frequently asked questions

How much does a Domene vacation package cost?
Offering great value package deals from $568 on Expedia, you'll be pleasantly surprised at how much a vacation to Domene costs! Expedia's packages make travel planning easier and save you more.
What are the cheapest months to go to Domene?
November, December and January are great times to search for cheap Domene vacation packages. Choosing to travel in quieter periods means you'll typically find reduced prices on hotels and flights.
How many days is enough for Domene?
With a well-planned itinerary, you can easily visit the top Domene attractions in a few days. But if you want to explore off the beaten track or take day trips, think about booking your Domene vacation for longer.
How to find the best Domene package deals?
Landing a cheap Domene package deal is a cinch with Expedia. After you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, apply some filters and browse what's available. You can fine-tune your search by "Popular locations," "Property type," "Guest rating" and more. Order the results by "Price: low to high" to discover the most affordable Domene package deals. Want a simple trick to get even more savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are typically lower.
Is it cheaper to book a Domene vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to arranging hotels and flights individually. Better still, you can personalize your Domene escape to match your exact style. Pick your preferred flight time, select the hotel type and add a rental car. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Domene?
Enjoy incredible bargains by reserving your flights ahead of time with Expedia. If being spontaneous is more your style, grab one of our last-minute deals for an impromptu Domene trip.
Does Expedia offer Book Now, Pay Later Domene vacation packages?
If you're anything like us, you love traveling but don't love the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With help from online lender Affirm, you can spread the total cost of your Domene trip over 3, 6 or 12 months. There are also no hidden or late payment fees, so you can snap up cheap vacation packages with payment plans as soon as you see them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.