Mill Spring Vacations from $1,017

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

The Latest Mill Spring vacation packages

Price found within the past 48 hours. Click for updated prices.
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
Price was $1,070, price is now $1,017 per person
$1,017
per person
Jan 24 - Jan 30
found 8 hours ago
Roundtrip non-stop flight included
Manhattan (MHK) to Cape Girardeau (CGI)
8/10 Very Good! (1,003 reviews)
The hallways reeked of marijuana smoke. Changed hotels the second night.

Reviewed on Nov 2, 2026

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

3 out of 5
Price was $1,133, price is now $1,087 per person
$1,087
per person
Jan 24 - Jan 30
found 8 hours ago
Roundtrip non-stop flight included
Manhattan (MHK) to Cape Girardeau (CGI)
9.4/10 Exceptional! (1,003 reviews)
Was really impressed, I don’t normally write reviews. Free drinks and food in the evening, lovely staff. clean room. Was really a cut above.

Reviewed on Nov 1, 2026

Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

3 out of 5
Price was $1,103, price is now $1,066 per person
$1,066
per person
Jan 24 - Jan 30
found 8 hours ago
Roundtrip non-stop flight included
Manhattan (MHK) to Cape Girardeau (CGI)
8.8/10 Excellent! (795 reviews)
Loved being able to eat dinner and breakfast at the hotel. After a long drive, thank you

Reviewed on Nov 2, 2026

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

2.5 out of 5
Price was $1,122, price is now $1,087 per person
$1,087
per person
Jan 24 - Jan 30
found 8 hours ago
Roundtrip non-stop flight included
Manhattan (MHK) to Cape Girardeau (CGI)
9.4/10 Exceptional! (992 reviews)

Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North

2.5 out of 5
Price was $1,069, price is now $1,038 per person
$1,038
per person
Jan 24 - Jan 30
found 8 hours ago
Roundtrip non-stop flight included
Manhattan (MHK) to Cape Girardeau (CGI)
7.8/10 Good! (442 reviews)

Don't see what you're looking for?
See all available trips from Columbus to Mill Spring
View all trips

Mill Spring Hotel Deals

Fall Getaway Cabin Bordering Mark Twain National Forest-Fire Pit & Private Trail

Fall Getaway Cabin Bordering Mark Twain National Forest-Fire Pit & Private Trail

Mill Spring MO
$158 nightly
The price is $167 total per night from Nov 3 to Nov 4
$167 total
Nov 3 - Nov 4
Total with taxes and fees
9.8/10 Exceptional! (6 reviews)
"Love how it was decorated"

Reviewed on Oct 4, 2026

Fall Getaway Cabin Bordering Mark Twain National Forest-Fire Pit & Private Trail
Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

2.5 out of 5
2420 Crestwood Dr Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $101 total per night from Nov 8 to Nov 9
$101 total
Nov 8 - Nov 9
Total with taxes and fees
Hampton Inn Poplar Bluff
Lake Wappapello

Lake Wappapello

2 out of 5
8005 Missouri 172 Williamsville MO
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $105 total per night from Nov 3 to Nov 4
$105 total
Nov 3 - Nov 4
Total with taxes and fees
Lake Wappapello
See all 147 properties in Mill Spring
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Mill Spring Vacation Packages

Mill Spring Essential Information

Language
English
Currency
U.S dollars

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Mill Spring vacation package cost?
You'll find cheap prices from $1,017 on Expedia for your Mill Spring break. However, a range of factors like the season, choice of hotel and length of stay will influence how much your vacation to Mill Spring costs.
What are the cheapest months to go to Mill Spring?
You're likely to find lower prices and better availability in February, November and December. Check out our cheap Mill Spring vacation packages and you could get some excellent off-season deals.
How many days is enough for Mill Spring?
With a well-organized schedule, you can easily visit the most popular Mill Spring attractions in a few days. But if you prefer to discover hidden gems or go on day tours, consider booking your Mill Spring vacation for longer.
How to find the best Mill Spring package deals?
Use Expedia's filter tool to help you find some of the best Mill Spring package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your break for midweek, or look for Mill Spring package deals in the off-peak season. Switch up your travel dates and you may score even bigger discounts. As a rule of thumb, it's usually best to lock in your vacation package as soon as possible.
Is it cheaper to book a Mill Spring vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your hotel, flight and car rental into one great-value price and enjoy significant savings. You'll typically score a better deal than booking each component individually. And you'll still enjoy the flexibility to create a customized Mill Spring vacation by choosing your favorite accommodation type, airline and car class.
When to book a vacation package to Mill Spring?
Secure amazing discounts by booking your flights in advance with Expedia. If spontaneity is more your thing, snap up one of our last-minute deals for an impromptu Mill Spring break.
Does Expedia offer Book Now, Pay Later Mill Spring vacation packages?
If you're anything like us, you love jet-setting around the world but are not a fan of the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With help from online lender Affirm, you can spread the cost of your Mill Spring break across 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can secure great vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.