Find hotels in Mill Spring, MO from $61

Start date: Check-in selected.
To Date
End date: Check-out

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 7 - Dec 8
Tomorrow
Dec 8 - Dec 9
Next weekend
Dec 12 - Dec 14
In two weeks
Dec 19 - Dec 21

Filter by

Guest rating
Guest rating
Star rating

Compare 127 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Breakfast, lunch, dinner served; Italian cuisine
Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

3.0 star property
Poplar Bluff
8.8 out of 10, Excellent, (696)
"Amazing place"
United States
Mladen
$110 nightly
The price is $124
Dec 14 - Dec 15
Total with taxes and fees
Holiday Inn Poplar Bluff by IHG
In-room safe, desk, free WiFi, bed sheets
Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri

2.0 star property
Poplar Bluff
6.6 out of 10, (622)
"The lady at the front was very nice. "
United States
Travis
$54 nightly
The price is $61
Dec 22 - Dec 23
Total with taxes and fees
Super 8 by Wyndham Poplar Bluff Missouri
Terrace/patio
Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (796)
"Staff was kind and provided a lot of information during check out."
United States
Shea
$94 nightly
The price is $106
Dec 14 - Dec 15
Total with taxes and fees
Hampton Inn Poplar Bluff
Lobby lounge
Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (851)
"Very clean, great check in"
United States
Teresa
$104 nightly
The price is $118
Jan 4 - Jan 5, 2026
Total with taxes and fees
Fairfield Inn & Suites by Marriott Poplar Bluff
Lobby
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (957)
"Delicious, well-ran breakfast and quiet peaceful hotel. "
United States
Janene
$94 nightly
The price is $106
Dec 11 - Dec 12
Total with taxes and fees
Drury Inn & Suites Poplar Bluff
Lobby
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2.0 star property
Poplar Bluff
7.8 out of 10, Good, (1004)
"Love the updated rooms and the vending area."
United States
Kathi
$76 nightly
The price is $80
Dec 9 - Dec 10
Total with taxes and fees
Motel 6 Poplar Bluff, MO
Lobby
Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North

2.5 star property
Poplar Bluff
7.8 out of 10, Good, (396)
"Good breakfast selection for the price and clean room. "
United States
Jared
$88 nightly
The price is $99
Jan 4 - Jan 5, 2026
Total with taxes and fees
Comfort Inn Poplar Bluff North
Fountain
Bullwinkles Rustic Lodge

Bullwinkles Rustic Lodge

2.5 star property
Poplar Bluff
8.4 out of 10, Very Good, (210)
"Great stay highly recommend "
United States
Brenden
$79 nightly
The price is $89
Dec 10 - Dec 11
Total with taxes and fees
Bullwinkles Rustic Lodge
Cabin
Sam A Baker State Park

Sam A Baker State Park

2.0 star property
Patterson
9.2 out of 10, Wonderful, (5)
"Pet friendly, great staff. "
United States
Charlie
$125 nightly
The price is $132
Dec 8 - Dec 9
Total with taxes and fees
Sam A Baker State Park
BBQ/picnic area
Current River Inn

Current River Inn

3.0 star property
Van Buren
8.2 out of 10, Very Good, (164)
"The mattresses were fabulous. Clean rooms and friendly staff. We will stay here again. The antique store and restaurants are walking distance. Nice family friendly establishment!"
United States
Thad
$98 nightly
The price is $107
Dec 16 - Dec 17
Total with taxes and fees
Current River Inn
Front of property
Lake Wappapello

Lake Wappapello

2.0 star property
Williamsville
10.0 out of 10, Exceptional, (1)
"We did loose internet connection so gps did not always help but the local stores did. Also the managers answered their phones and were so helpful in many ways! I’m very glad we went."
United States
Dyann
$138 nightly
The price is $146
Dec 10 - Dec 11
Total with taxes and fees
Lake Wappapello
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Mill Spring Hotel Reviews

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

10/10 Excellent
"Every single time I come to this location, it always exceeds my expectations. It's always clean.They always have hot coffee and they are super friendly!! Never have anything bad to say about them"
Samantha 1-night trip
Posted 4 days ago
Hampton Inn Poplar Bluff

More cheap stays in Mill Spring

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

4101 Highway 67 N Poplar Bluff MO
$76 nightly
The price is $80 total per night from Dec 9 to Dec 10
$80 total
Dec 9 - Dec 10
Total with taxes and fees
7.8/10 Good! (1,003 reviews)

Hotels in Mill Spring with star-rating

Frequently asked questions

Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Mill Spring hotel for you.
How can I save on a Mill Spring hotel booking with Expedia?
One Key™ - Expedia's free travel rewards program - gives you instant access to perks and Member Prices on Mill Spring hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings.

*OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Mill Spring hotel?
Prices for hotels in Mill Spring often vary, but you can find a great deal from $61 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia