Palmyra Vacations from $611
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Your Palmyra Vacation
Book a Palmyra vacation package and prepare for a fabulous adventure. Known for its rich history and friendly locals, there's plenty to keep you on the move in this lively city. Fill your trip to Palmyra with tours of its leading attractions. First stop? Make a beeline for Gardner House Museum. Expedia is here to help you escape the everyday. Tailor your vacation to Palmyra to suit your travel style, whatever that may be.
The Latest Palmyra Vacation Packages
- Knights Inn Kirksville
Feb 5 - Feb 7Knights Inn Kirksville + Flight
Kirksville2 nights1.5 star property7.4/10 - Good (277 reviews)Roundtrip • Knoxville (TYS) - Columbia (COU)TYS - IRK • 1 stop IRK - TYS • 1 stop$611found 1 day agoper traveler - Hampton Inn Kirksville
Feb 5 - Feb 7Hampton Inn Kirksville + Flight
Kirksville2 nights2.5 star property9.2/10 - Wonderful (709 reviews)"Very nice hotel overall. Our king size room was spacious and had a sofa that would fold out for another guest, but was nice to sit on and watch tv, with a table to put snacks on, etc. Also a desk with chair and several ottomans to put your feet up while relaxing, or to sit on. The bathroom was spacious with a large walk-in shower and lots of counter space with pull-out drawers. Multiple hooks for hanging towels and clothing as well. Breakfast was awesome- lots of food choices, hot or cold,..."Reviewed November 11, 2026Roundtrip • Knoxville (TYS) - Columbia (COU)TYS - IRK • 1 stop IRK - TYS • 1 stop$676$659found 1 day agoper traveler - Holiday Inn Express & Suites Kirksville - University Area by IHG
Feb 5 - Feb 7Holiday Inn Express & Suites Kirksville - University Area by IHG + Flight
Kirksville2 nights2.5 star property9.2/10 - Wonderful (582 reviews)Roundtrip • Knoxville (TYS) - Columbia (COU)TYS - IRK • 1 stop IRK - TYS • 1 stop$672$667found 1 day agoper traveler - Super 8 by Wyndham Kirksville-University Area
Feb 5 - Feb 7Super 8 by Wyndham Kirksville-University Area + Flight
Kirksville2 nights2.5 star property8.8/10 - Excellent (295 reviews)"Check in was quick and easy, but upon going to my room, I noticed the bathtub hadn’t been cleaned and the towels were dirty. I informed the young lady at the front desk, and she only gave me fresh towels, but nobody ever came to properly clean thethe bathtub. Later in the evening, I tried watching TV and it wasn’t functioning properly, and at 10 p.m., a young man came to the room to try and figure it it, but after trying for nearly an hour, he was unsuccessful. He said he tried reaching out the..."Reviewed November 9, 2026Roundtrip • Knoxville (TYS) - Columbia (COU)TYS - IRK • 1 stop IRK - TYS • 1 stop$626$623found 1 day agoper traveler - Quality Inn Kirksville
Feb 5 - Feb 7Quality Inn Kirksville + Flight
Kirksville2 nights2.5 star property7.6/10 - Good (417 reviews)"Dirty room and sheets. Air Conditioning was broken."Reviewed October 30, 2026Roundtrip • Knoxville (TYS) - Columbia (COU)TYS - IRK • 1 stop IRK - TYS • 1 stop$625found 1 day agoper traveler
Where to stay near Palmyra
Quincy
For travelers seeking a memorable trip, Quincy offers a delightful blend of outdoor activities, cultural experiences, and scenic beauty. Just a short drive from Palmyra, this vibrant city is home to attractions like the historic Quincy University and the enchanting Villa Katherine Castle, perfect for exploration. Visitors can also enjoy events at the Oakley Lindsay Center, making Quincy an ideal base for both family getaways and business trips. With its convenient location and diverse offerings, Quincy is a smart choice for your stay.
Hannibal
Experience the charm of Hannibal, a delightful hub for travelers looking for a mix of culture and outdoor adventure. Just a short drive from Palmyra, this picturesque city offers attractions like the Mark Twain Cave, where you can explore fascinating underground passages, and the Mark Twain Boyhood Home and Museum, which brings the author's early life to life. With its scenic lake and national state park nearby, Hannibal is an ideal choice for a weekend getaway or family vacation, making it a smart hotel booking option.
Rensselaer
Make your vacation planning effortless by staying in Rensselaer, a haven for nature and family travelers due to its close proximity to attractions like Bear Creek Park and the Gardner House Museum. Here, you can enjoy outdoor activities and explore the local parks, while also being just about a 12-mile drive from Palmyra. Rensselaer offers a blend of leisure and entertainment, making it a smart choice for your stay.
Taylor
Immerse yourself in Taylor, where family-oriented travelers can easily access outdoor adventures and serene nature experiences. This charming city is about 10 miles by car from Palmyra, making it an ideal base for exploring local highlights like the Oakley Lindsay Center, Quincy University, and the scenic Wakonda State Park. With seasonal peaks in visitor arrivals from March to April and September, Taylor offers a vibrant atmosphere for those seeking eco-friendly activities and recreational fun. Choosing Taylor for your stay ensures a delightful blend of comfort and adventure.
West Quincy
Travelers visiting the area often choose West Quincy, especially families and outdoor enthusiasts seeking budget-friendly accommodations. This charming village offers access to activities like golf and mini golf, along with nearby attractions such as the historic Quincy University and the picturesque Villa Katherine Castle. Located about 14 miles by car from Palmyra, West Quincy provides a perfect base for exploring the local scenery and engaging in adventure sports. It's a smart choice for your stay, blending comfort and convenience seamlessly.
Discover the most popular places to visit in Palmyra
Palmyra Hotel Deals
Quality Inn & Suites Hannibal West
Quality Inn & Suites Hannibal West"Had to wait for someone to come to the front desk for 10 minutes when we arrived. The pool was cold and dirty. The room the pool was in was dirty and dusty. There were no pool towels available, even though we wouldn’t have gotten in anyway. The hot tub did not work and was very dirty. There was hair all over the bathroom floor when we got into our room. Breakfast was average."
Sleep Inn & Suites Hannibal West
Sleep Inn & Suites Hannibal West"Perfect location to stay on our way to Paola KS for a wedding. We enjoyed visiting downtown Hannibal. Walking along the Mississippi River and had an excellant dinner at The Wolfhound Pub!"
"The price was good. The bathroom was not clean. The tub was caulked around edges trying to cover up the mold underneath. But it was coming thru again. The toilets are cramped in and made for children, not adults with knee issues. The sheets on bed were debatable as to being changed. Extremely wrinkled like someone had been in them. ?? We had to fix the knobs on both bathroom doors. We carry a small toolkit, so just fixed as the gal was working alone. My brother had gotten locked in bathroom...
"N/a"
"Great rate for a quick overnight stop. We didn't stay late enough for breakfast. The room was very clean, but the window latches were unlocked. I only noticed this because the curtain was open and I happened to notice as I was closing it. Our room was on the first floor and accessible from the parking lot through that window, so that was a little disconcerting. However, the front desk clerk got us checked in quickly, beds were comfy, and again the room was clean."
"Clean room and staff were amazing. Breakfast was what I expected. Rooms are incredibly dated and needs repair."
Frequently Asked Questions
How much does a Palmyra vacation package cost?
Offering excellent value package deals from $611 on Expedia, you'll be thrilled with how little a vacation to Palmyra costs! Our packages mean less travel planning for you and greater savings.
What are the cheapest months to go to Palmyra?
You can usually find lower rates and greater availability in June, August and December. Explore our cheap Palmyra vacation packages and you could get some great off-season discounts.
How many days is enough for Palmyra?
The ideal length of your Palmyra vacation depends on what you'd like to do and see. Usually, a few days to a week will give you enough time to go to all the main attractions and discover some hidden treasures along the way.
How to find the best Palmyra package deals?
Begin your search for a Palmyra package deal by entering your destination and preferred trip dates under our "Packages" tab. Then apply some filters, like "Property type" and "Guest rating," to fine-tune the results to your exact style. You can also sort by "Package discount" and browse offers that come with huge savings. If you don't find the perfect Palmyra package deal straight away, just change your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Palmyra getaway off to a flying start.
Is it cheaper to book a Palmyra vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your hotel, flight and car rental into one great-value price and you could save hundreds of dollars. You'll generally get a better deal than booking each component separately. And you'll still enjoy the flexibility to create a customized Palmyra vacation by choosing your preferred type of stay, airline and car class.
When to book a vacation package to Palmyra?
Score incredible discounts by booking your flights ahead of time with Expedia. If spontaneity is more your style, grab one of our last-minute deals for a spur-of-the-moment Palmyra break.
Does Expedia offer Book Now, Pay Later Palmyra vacation packages?
Set off on your dream getaway to Palmyra with our Book Now, Pay Later vacations. No need to save up or hold off until the next payday — we've teamed up with online lender Affirm to give you more flexibility with your finances. Our vacation packages with payment plans let you spread the total cost over 3, 6 or 12 months. With no late payment fees or extra charges, it's easy to budget for your trip and snap up bargains before they disappear.