South Eastern Region Vacations & Trips from $853

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Your South Eastern Region Vacation

With a South Eastern Region vacation package, you can forget about the stress of planning and just focus on experiencing all this lively destination has on offer. You'll have a long to-do list during your trip to South Eastern Region. One top city you'll want to explore is Valletta. Expedia has flights, hotels and everything else you need to help you create your own customized South Eastern Region vacation today.

Top destinations in South Eastern Region

The Latest South Eastern Region Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Avalon Boutique
Iniala Harbour House
The Capital Boutique Hotel
Hotel Pjazza Merkanti - Boutique Living
Osborne

Black Friday Sale

Limited-time deals: Save up to 50% on select hotels.

Where to stay in South Eastern Region

Get a lay of the land and find the perfect place to stay Learn more about South Eastern Region

Find the Best South Eastern Region Vacation Packages

South Eastern Region Essential Information

Language
Maltese
Currency
Euros
Local Welcome
Hawn
Local Goodbye
Ċaw
Top Sights
Upper Barrakka Gardens, Lower Barrakka Gardens and Marsaxlokk Bay

South Eastern Region Hotel Deals

Grand Hotel Excelsior

Grand Hotel Excelsior

5 out of 5
Great Siege Road Floriana Malta
Fully refundableReserve now, pay when you stay
8.6/10 Excellent! (1,009 reviews)
Quiet, close to the city center. Great housekeeping and customer service

Reviewed on Nov 23, 2025

Grand Hotel Excelsior
Palais Le Brun

Palais Le Brun

4.5 out of 5
101 old bakery street Valletta
Fully refundableReserve now, pay when you stay
$183 nightly
The price is $197 total per night from Dec 1 to Dec 2
$197 total
Dec 1 - Dec 2
Total with taxes and fees
9.4/10 Exceptional! (801 reviews)
Lovely helpful staff. Spacious room and very clean. Cleaned every day

Reviewed on Nov 25, 2025

Palais Le Brun
The Gomerino Hotel

The Gomerino Hotel

4 out of 5
247 St Paul St Valletta
Fully refundableReserve now, pay when you stay
$203 nightly
The price is $219 total per night from Dec 1 to Dec 2
$219 total
Dec 1 - Dec 2
Total with taxes and fees
9.6/10 Exceptional! (948 reviews)
Everything to me the staff at the hotel are fantastic the hotel is beautiful and the surrounding area is very good and easy with plenty of restaurants and shops museums just a fantastic place to visit

Reviewed on Nov 28, 2025

The Gomerino Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in South Eastern Region

What to do in South Eastern Region

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.