Sant' Ambrogio Vacations from $886

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Your Sant Ambrogio Vacation

Make travel planning simple by locking in a vacation package to Sant Ambrogio. We'll take care of the finer points, so you can concentrate on discovering everything this neighborhood can offer. Your trip to Sant Ambrogio wouldn't be complete without seeing leading attractions nearby such as Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia will help turn your dream Sant Ambrogio vacation into reality, whatever your budget or travel plans.

The Latest Sant' Ambrogio Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Aurum Firenze

Aurum Firenze

4 out of 5
Historic Centre of Florence
Save 100% on your flight
Price was $1,569, price is now $886 per person
$886
per person
Oct 16 - Oct 21
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.6/10 Good! (1,008 reviews)
Close to centre of Florence, room ok, clean

Reviewed on Aug 28, 2025

Villa di Piazzano - Small Luxury Hotel of the World

Villa di Piazzano - Small Luxury Hotel of the World

5 out of 5
Save 100% on your flight
Price was $3,426, price is now $2,117 per person
$2,117
per person
Oct 12 - Oct 17
found 1 day ago
Roundtrip flight included
New York (NYC) to Florence (FLR)
9.8/10 Exceptional! (220 reviews)
Este hotel es excepcionalmente bello, unico y perfecto para unas vacaciones en la Toscana. La propiedad esta impecable al igual que las habitaciones, super limpias, cómodas y A/C super fuerte (no muy comunes en Europa) Staff fue muy amable y la cena espectacular. Es un deleite caminar la propiedad. Literalmente en cada metro puede tomarte una foto de ensueños. Recomendamos este hotel 200%. Esta a solo minutos de Cortona una linda ciudad para visitar. Villa de Piazzano te dejara en shock con su belleza desde que vienes por la carretera entre una hilera interminable de pinos cipreses. Simplemente Stunning.

Reviewed on Aug 20, 2025

Aurum Uffizi

Aurum Uffizi

4 out of 5
Historic Centre of Florence
Save 100% on your flight
Price was $2,028, price is now $1,091 per person
$1,091
per person
Oct 2 - Oct 7
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.8/10 Good! (1,004 reviews)
Very clean, aircon definitely welcome in summer temperatures, breakfast buffet very good. All within walkable distance of the Palazzo Vecchio and other attractions.

Reviewed on Aug 30, 2025

Cala Beach Resort

Cala Beach Resort

5 out of 5
Save 100% on your flight
Price was $3,368, price is now $1,880 per person
$1,880
per person
Oct 4 - Oct 9
found 15 hours ago
Roundtrip flight included
New York (JFK) to Florence (FLR)
10/10 Exceptional! (1 review)
Palazzo Firenze by Baglioni Hotels & Resorts

Palazzo Firenze by Baglioni Hotels & Resorts

5 out of 5
Historic Centre of Florence
Save 100% on your flight
Price was $17,174, price is now $10,463 per person
$10,463
per person
Oct 5 - Oct 10
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.4/10 Exceptional! (230 reviews)
Gorgeous boutique hotel, like museum Beautiful rooms!!! Thank you Giovanni for all ur help and knowledge organizing everything for us, and breakfast waiters were great!!!

Reviewed on Aug 21, 2025

Where to stay in Sant' Ambrogio

Find the best Sant' Ambrogio areas and neighborhoods for the activities you enjoy most. Learn more about Sant' Ambrogio
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Find hotels in Historic Centre of Florence

Sant' Ambrogio Hotel Deals

Hotel Bodoni

Hotel Bodoni

2 out of 5
Via Martiri del Popolo, 27, Florence, FI
$112 nightly
The price is $134 total per night from Sep 2 to Sep 3
$134 total
Sep 2 - Sep 3
Total with taxes and fees
Hotel Bodoni
Hotel Regency

Hotel Regency

5 out of 5
Piazza M. D'Azeglio, 3, Florence, FI
Fully refundableReserve now, pay when you stay
$499 nightly
The price is $568 total per night from Sep 1 to Sep 2
$568 total
Sep 1 - Sep 2
Total with taxes and fees
Hotel Regency
Hotel Bavaria

Hotel Bavaria

1 out of 5
Borgo Albizi 26, Florence, FI
$121 nightly
The price is $142 total per night from Sep 1 to Sep 2
$142 total
Sep 1 - Sep 2
Total with taxes and fees
Hotel Bavaria
See all 492 properties in Sant' Ambrogio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Sant' Ambrogio

Great Synagogue of Florence

Learn about the local history of Florence with a stop at Great Synagogue of Florence. Visit the stunning cathedral and notable monuments in this vibrant area.

Great Synagogue of Florence

Piazza Massimo D'Azeglio

Find out about the history of Florence when you take a trip to Piazza Massimo D'Azeglio. Stroll along the riverfront or visit the notable monuments in this vibrant area.

Piazza Massimo D'Azeglio

Piazza Donatello

You can learn about the history of Florence with a stop at Piazza Donatello. Stroll along the riverfront or visit the churches in this vibrant area.

Piazza Donatello

Things to do

Florence: Pasta Cooking Class with Unlimited Wine

Florence: Pasta Cooking Class with Unlimited Wine

$33
per adult
94% of travellers recommend
Florence: Pasta Cooking Class with Unlimited Wine
Pasta Lovers cooking class: learn to cook tagliatelle ravioli and tiramisù

Pasta Lovers cooking class: learn to cook tagliatelle ravioli and tiramisù

$40
per adult
Pasta Lovers cooking class: learn to cook tagliatelle ravioli and tiramisù
Cooking Art Brunelleschi

Cooking Art Brunelleschi

$51
per adult
Cooking Art Brunelleschi
See all activities in Florence
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.