Sant' Ambrogio
Florence
Visit Sant' Ambrogio
Popular places to visit
Uffizi Gallery
Art lovers will be in their element in this famous museum, home to the most extensive and important collection of masterpieces in the world.
Ponte Vecchio
Take a trip over Florence’s iconic bridge, spared by the Nazis for its beauty and home to jewelers for more than four centuries.
Cathedral of Santa Maria del Fiore
The “Saint Mary of the Flower” cathedral and its towering dome have come to symbolize Florence.
Pitti Palace
This former royal residence now showcases the extensive collections of the Medici family, with seven galleries containing some of the finest artworks in Florence.
Piazza di Santa Maria Novella
Relax before or after a long trip in this renovated piazza just a few minutes from Florence’s main train station.
Piazza del Duomo
Giotto’s Bell Tower, the resplendent Baptistery, as well as the cathedral and its dome draw the crowds to this square in the heart of the city.
Things to do
City Sightseeing Florence Hop-on Hop-off Bus Tour
The Best of Tuscany in One Day Sightseeing Tour
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
Florence Half Day Tour with Michelangelo’s David, Accademia & Uffizi Option
Florence: Pasta exclusive making cooking class with Gelato
Florence: Pasta Cooking Class with Unlimited Wine
Sant' Ambrogio Hotel Deals
Hotel Bodoni
"Great location, clean and welcoming. It’s easy to get in, just click labeled button and they’ll let you in. Lovely rooftop, breakfast, etc."
Reviewed on May 31, 2026
Hotel Regency
"The breakfast was delicious, a wide variety. Service was excellent, quite responsive and attentive staff."
Reviewed on Apr 12, 2026
Hotel Bavaria
"Je ne me souviens pas que dans la description on parlait d’une salle de bain partagée, à l’extérieur de la chambre. Ceci dit, ce fut très bien. Personnel courtois, hébergement bien entretenu. À savoir: pas d’ascenseur et de quand même pas mal de marches à monter. Une fois sur place, tout est ..."
Reviewed on May 31, 2026
Villa Tortorelli
"Very intimate setting, welcoming kind staff. Pretty trees and view from the terrace."
Reviewed on May 19, 2026
The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World
"The Hotel is beautiful and very well appointed. The staff is even better than the hotel itself! Would absolutely stay here again and recommend to all friends and family!"
Reviewed on Apr 6, 2026
Hotel Villa Liana
"clean, spacious, well-stocked with toiletries and breakfast items too. walkable distance to all iconic sites. Grace, the breakfast host, did an incredible job, very welcoming & served with options for hot coffee drinks. All together, wonderful, memorable stay!!"
Reviewed on May 23, 2026
Other neighborhoods around Sant' Ambrogio
Santa Croce
Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.
Santissima Annunziata
Travelers come to Santissima Annunziata for its colorful gardens, and you can see top attractions like Piazza Massimo D'Azeglio and Santissima Annunziata Square while you're in town.
Duomo
Uffizi Gallery and Via de' Calzaiuoli are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
San Giovanni
If you're spending some time in San Giovanni, Uffizi Gallery and Piazza della Repubblica are top sights worth seeing.
San Niccolò
If you're spending some time in San Niccolò, Arno River and Piazzale Michelangelo are top sights worth seeing.
Sant' Ambrogio
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