Sant' Ambrogio

Florence

A street artist painting on a sidewalk in front of a building with a large sign advertising a local business.
A panoramic view of a historic city with a river, bridges, and prominent towers.
An aerial view of a city with a river running through it, surrounded by hills.

Stay near popular Sant' Ambrogio attractions

Great Synagogue of Florence

9.0/10 (6 reviews)
Great Synagogue of Florence is just one of the places to see in Florence, so why not enjoy the other things to explore during your travels? Experience the fascinating museums and acclaimed art scene in this vibrant area.
See properties

Things to do

Picture 1 for Activity Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine

Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine

$20
per adult
94% of travellers recommend
Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine
City Sightseeing Florence Hop-on Hop-off

City Sightseeing Florence Hop-on Hop-off Bus Tour

$26
per adult
74% of travellers recommend
City Sightseeing Florence Hop-on Hop-off Bus Tour
Michaelangelo's David

Accademia timed-entry Ticket with App Guide

$44
per adult
90% of travellers recommend
Accademia timed-entry Ticket with App Guide
Florence: Pasta Cooking Class with Unlimited Wine

Florence: Pasta Cooking Class with Unlimited Wine

$20
per adult
94% of travellers recommend
Florence: Pasta Cooking Class with Unlimited Wine
The Best of Tuscany in One Day Sightseeing Tour

The Best of Tuscany Tour: Siena, San Gimignano, Pisa and Lunch at a Winery

$90
per adult
98% of travellers recommend
The Best of Tuscany Tour: Siena, San Gimignano, Pisa and Lunch at a Winery
People riding scooters in Tuscany

Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine

$146
per adult
98% of travellers recommend
Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine
See all activities in Florence

Sant' Ambrogio Hotel Deals

Hotel Bodoni

Hotel Bodoni

2 out of 5
Via Martiri del Popolo, 27 Florence FI
Fully refundable
$64 nightly
The price is $81 total per night from Nov 22 to Nov 23
$81 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (892 reviews)
"Right in downtown :) Quiet-Friendly staff ! great Breakfast ! Clean room Fridge-small Bathroom with shower that makes everything wet . Great rooftop views. Patio Elevator"

Reviewed on Oct 30, 2026

Hotel Bodoni
Hotel Bavaria

Hotel Bavaria

1 out of 5
Borgo Albizi 26 Florence FI
$56 nightly
The price is $69 total per night from Nov 23 to Nov 24
$69 total
Nov 23 - Nov 24
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, daily housekeeping, and concierge services. Our guests praise the helpful staff in our reviews. Popular attractions ...
Hotel Bavaria
Hotel Regency

Hotel Regency

5 out of 5
Piazza M. D'Azeglio, 3 Florence FI
$313 nightly
The price is $362 total per night from Nov 30 to Dec 1
$362 total
Nov 30 - Dec 1
Total with taxes and fees
Book a stay at this luxury hotel in Florence. Enjoy free breakfast, free WiFi, and 24-hour room service. Our guests praise the helpful staff in our reviews. ...
Hotel Regency
Palazzo dei Ciompi Suites

Palazzo dei Ciompi Suites

Via Pietrapiana 18 Florence FI
$60 nightly
The price is $80 total per night from Dec 1 to Dec 2
$80 total
Dec 1 - Dec 2
Total with taxes and fees
Book a stay at this luxury aparthotel in Florence. Enjoy 2 restaurants, breakfast (surcharge), and WiFi (surcharge). Popular attractions Piazza del Duomo and ...
7.6/10 Good! (424 reviews)
"Room was clean. Staff was very helpful. Location was central. Air conditioning was not sufficient. We had a few rainy days with lot of humidity. They provided free washer and dryer. Otherwise I would still recommend this hotel."

Reviewed on Oct 22, 2026

Palazzo dei Ciompi Suites
The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

5 out of 5
Via di Mezzo 20 Florence FI
$434 nightly
The price is $496 total per night from Nov 15 to Nov 16
$496 total
Nov 15 - Nov 16
Total with taxes and fees
Book a stay at this luxury hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Popular attractions Piazza del Duomo and Ponte Vecchio are located ...
The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World
Villa Tortorelli

Villa Tortorelli

Piazza Massimo D'Azeglio 39 Florence FI
$82 nightly
The price is $104 total per night from Dec 1 to Dec 2
$104 total
Dec 1 - Dec 2
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
Villa Tortorelli
See all 553 properties in Sant' Ambrogio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sant' Ambrogio

Find the best Sant' Ambrogio areas and neighborhoods for the activities you enjoy most. Learn more about Sant' Ambrogio
Learn more about Sant' Ambrogio
A river with buildings on the right bank.

Historic Centre of Florence

Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza del Duomo and Piazza di Santa Maria Novella are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

A historic church with intricate architecture and a large open plaza with people.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Florence.

A historic building with intricate architectural details, including a dome and ornate facades.

Duomo

Piazza del Duomo and Piazza di Santa Maria Novella are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

A historic bridge with arches over a river, surrounded by yellow buildings and a crowd of people.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

A grand cathedral with intricate architectural details, including statues and ornate decorations.

Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Sant' Ambrogio

Choose one or more items to build your trip:

Explore a world of travel with Expedia