A vineyard with rows of grapevines.

Santa Cruz Vacation Rentals

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Check prices for these dates

In two weeks
Nov 27 - Nov 29
In two months
Jan 8 - Jan 10
In three months
Feb 5 - Feb 7
In four months
Mar 5 - Mar 7

Our top choices for Santa Cruz vacation rentals

A rustic cabin with a wooden deck, surrounded by lush greenery and a mountainous backdrop.

1. Colchagua Tiny Lodge

Colchagua Tiny Lodge
3.5 star property
Santa Cruz
9.8 out of 10, Exceptional, (12 reviews)
"Cute lodge with friendly staff that helps you to your cozy room- sets up your hot tub and brings an amazing basket for breakfast! Can’t wait to go back "
United States
Jonathan
$181 nightly
The price is $181
Nov 21 - Nov 22
Colchagua Tiny Lodge
A dining area with a glass table, grey upholstered chairs, and a blue water bottle.

2. House in a natural setting

House in a natural setting
Curico
$80 nightly
The price is $93
Nov 22 - Nov 23
House in a natural setting
A bedroom with a bed, a nightstand, a window, and a view of buildings outside.

3. The Most Comfortable Apartment in San Fernando

The Most Comfortable Apartment in San Fernando
San Fernando
$123 nightly
The price is $123
Nov 16 - Nov 17
The Most Comfortable Apartment in San Fernando
A wooden hot tub with a metal stand and a wooden bench.

4. Refugio Campestre, Cabin with a Tinaja (Bathtub)

Refugio Campestre, Cabin with a Tinaja (Bathtub)
Chimbarongo
$60 nightly
The price is $60
Nov 18 - Nov 19
Refugio Campestre, Cabin with a Tinaja (Bathtub)
A cozy outdoor seating area with string lights, potted plants, and a wooden bench.

5. Hostel Turismo San Vicente Tagua Tagua

Hostel Turismo San Vicente Tagua Tagua
San Vicente de Taguatagua
$67 nightly
The price is $67
Nov 15 - Nov 16
Hostel Turismo San Vicente Tagua Tagua
A covered patio with a glass table, wicker furniture, hanging planters, and a view of a lush garden.

6. Fully furnished house in Curico, centrally located, with covered parking

Fully furnished house in Curico, centrally located, with covered parking
Curicó
$92 nightly
The price is $107
Nov 15 - Nov 16
Fully furnished house in Curico, centrally located, with covered parking
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Santa Cruz Plaza

Santa Cruz Plaza

10/10 Excellent
"The service from the staff is immaculate. The properly full of charm and character. The rooms are spacious, clean and comfortable"
Darren 1-night trip
Posted 11 days ago
Santa Cruz Plaza

Find out more about Santa Cruz

Everything you need to know about Santa Cruz vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Cruz vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Cruz in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $60 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, there are vacation rentals in Santa Cruz close to Colchagua Campo y Vino, or you can choose a more secluded option if you want a relaxing stay. Our travelers say Santa Cruz has a good selection of wineries and the restaurants. Make sure you have time to check out the local tours and casinos during your trip.

What's the top vacation rental that Santa Cruz has to offer?

Hostel Turismo San Vicente Tagua Tagua: This vacation home rental outside of Santa Cruz has laundry facilities and WiFi to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms and a kitchenette with kitchenware.

What can I see and do in Santa Cruz?

Cultural attractions include Museo de Colchagua, whereas Millahue Valley is a spot to enjoy nature. Casino Colchagua and Colchagua Campo y Vino are other places to visit while you're in town.

What are vacation rentals like in Santa Cruz?

Vacation rentals are private properties you can stay in for several days or longer in Santa Cruz. Vacation rentals feature amenities such as patios, hot tubs, and fire pits so you'll feel just like you're staying in your own home. If you're concerned about a clean environment, a vacation rental can offer a sense of safety away from shared hotel elevators and busy lobbies while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a hotel, which makes a vacation rental a popular option for a family getaway.