Title: Santa Cruz Vacation Rentals from $71: Search Short-Term Rentals | Expedia.com

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![Rows of vineyards, Santa Cruz, Chile](https://images.trvl-media.com/place/6047957/e58d3014-ef10-4c60-9e03-08890e2f5494.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=6047957&startDate=2026-03-20&endDate=2026-03-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 1 - May 3](https://www.expedia.com/Hotel-Search?regionId=6047957&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 29 - May 31](https://www.expedia.com/Hotel-Search?regionId=6047957&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 26 - Jun 28](https://www.expedia.com/Hotel-Search?regionId=6047957&startDate=2026-06-26&endDate=2026-06-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santa Cruz vacation rentals

![1 bedroom, laptop workspace, soundproofing, free WiFi](https://images.trvl-media.com/lodging/113000000/112020000/112019700/112019659/a6261078.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/113000000/112020000/112019700/112019659/2934ee8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bathtub, free toiletries, hair dryer, bathrobes](https://images.trvl-media.com/lodging/113000000/112020000/112019700/112019659/18aa40d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/113000000/112020000/112019700/112019659/0501d5fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabin in Santa Cruz

[](https://www.expedia.com/Santa-Cruz-Hotels-Colchagua-Tiny-Lodge.h112019659.Hotel-Information)

9.8/10

Exceptional

(8 reviews)

"The Tiny Lodge has so many amenities thoughtfully packed into a cozy package. Loved the thought put into surfaces and spaces to sit your personal belongings. The bed is luxurious. 10 out of 10\. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Trisha

$184 nightly

$184 total

Mar 10 - Mar 11

[](https://www.expedia.com/Santa-Cruz-Hotels-Colchagua-Tiny-Lodge.h112019659.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/39000000/38120000/38118300/38118253/48553e33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi](https://images.trvl-media.com/lodging/39000000/38120000/38118300/38118253/4fb40573.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/39000000/38120000/38118300/38118253/a038bdc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/39000000/38120000/38118300/38118253/b9cfe331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Santa Cruz

[](https://www.expedia.com/Santa-Cruz-Hotels-The-Ambush-Field-And-Comfort.h38118253.Hotel-Information)

$166 nightly

$194 total

Mar 7 - Mar 8

[](https://www.expedia.com/Santa-Cruz-Hotels-The-Ambush-Field-And-Comfort.h38118253.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/94000000/93190000/93188700/93188687/db0556a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/94000000/93190000/93188700/93188687/3f23d36b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/94000000/93190000/93188700/93188687/5ff8a12e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, soap, shampoo](https://images.trvl-media.com/lodging/94000000/93190000/93188700/93188687/b6b66859.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in San Vicente de Taguatagua

[](https://www.expedia.com/San-Vicente-Hotels-Hostel-Turismo-San-Vicente-Tagua-Tagua.h93188687.Hotel-Information)

$79 nightly

$79 total

Mar 7 - Mar 8

[](https://www.expedia.com/San-Vicente-Hotels-Hostel-Turismo-San-Vicente-Tagua-Tagua.h93188687.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/120000000/119240000/119237300/119237202/b1e5a2d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hair dryer, towels, soap, toilet paper](https://images.trvl-media.com/lodging/120000000/119240000/119237300/119237202/da3e2cf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/120000000/119240000/119237300/119237202/ef1b9b5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/120000000/119240000/119237300/119237202/b0a32316.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cottage in Curico

[](https://www.expedia.com/Teno-Hotels-House-In-A-Natural-Setting.h119237202.Hotel-Information)

$93 nightly

$107 total

Mar 12 - Mar 13

[](https://www.expedia.com/Teno-Hotels-House-In-A-Natural-Setting.h119237202.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/121000000/120830000/120821100/120821060/64aa2b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/121000000/120830000/120821100/120821060/1965fb23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/121000000/120830000/120821100/120821060/689eef75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/121000000/120830000/120821100/120821060/e5b1788f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabin in Chimbarongo

[](https://www.expedia.com/Chimbarongo-Hotels-Vrbo-Property.h120821060.Hotel-Information)

$71 nightly

$71 total

Mar 8 - Mar 9

[](https://www.expedia.com/Chimbarongo-Hotels-Vrbo-Property.h120821060.Hotel-Information)

![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/117000000/116740000/116738800/116738795/bd08745e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/117000000/116740000/116738800/116738795/a9e9f4ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/117000000/116740000/116738800/116738795/cb86fe34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/117000000/116740000/116738800/116738795/d58c976f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in San Fernando

[](https://www.expedia.com/San-Fernando-Hotels-Vrbo-Property.h116738795.Hotel-Information)

$138 nightly

$138 total

Mar 9 - Mar 10

[](https://www.expedia.com/San-Fernando-Hotels-Vrbo-Property.h116738795.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/124000000/123780000/123777400/123777358/58ef3ff1_edited_6d5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/124000000/123780000/123777400/123777358/ddfe58f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/124000000/123780000/123777400/123777358/9abb34f0_edited_f464.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/124000000/123780000/123777400/123777358/b09f5fdb_edited_2c1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Santa Cruz

[](https://www.expedia.com/Peralillo-Hotels-Beautiful-5-Bedroom-Home-Near-Santa-Cruz-Perfect-For-Your-Getaway.h123777358.Hotel-Information)

$460 nightly

$460 total

Mar 7 - Mar 8

[](https://www.expedia.com/Peralillo-Hotels-Beautiful-5-Bedroom-Home-Near-Santa-Cruz-Perfect-For-Your-Getaway.h123777358.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-20&endDate=2026-03-21&regionId=6047957&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

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## 

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Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

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## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+O%27Higgins+Region%2C+Chile&regionId=6047957&latLong=-34.640343%2C-71.365997&adults=2&startDate=2026-06-03&d1=2026-06-03&endDate=2026-06-06&d2=2026-06-06&lodging=CABIN)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+O%27Higgins+Region%2C+Chile&regionId=6047957&latLong=-34.640343%2C-71.365997&adults=2&startDate=2026-06-03&d1=2026-06-03&endDate=2026-06-06&d2=2026-06-06&lodging=VACATION_HOME)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+O%27Higgins+Region%2C+Chile&regionId=6047957&latLong=-34.640343%2C-71.365997&adults=2&startDate=2026-06-03&d1=2026-06-03&endDate=2026-06-06&d2=2026-06-06&lodging=APARTMENT)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+O%27Higgins+Region%2C+Chile&regionId=6047957&latLong=-34.640343%2C-71.365997&adults=2&startDate=2026-06-03&d1=2026-06-03&endDate=2026-06-06&d2=2026-06-06&lodging=COTTAGE)

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## Top Santa Cruz Hotel Reviews

![Santa Cruz Plaza](https://images.trvl-media.com/lodging/2000000/1410000/1406700/1406642/3fe1c8d9_y.jpg)

### Santa Cruz Plaza

8/10 Good

"Mostly clean room, wonderful staff"

[](https://expedia.com/San-Fernando-Hotels-Santa-Cruz-Plaza.h1406642.Hotel-Information)

![TerraViña](https://images.trvl-media.com/lodging/4000000/3780000/3775300/3775207/5e3744e0_y.jpg)

### TerraViña

10/10 Excellent

"What a beautiful hotel! Excellent generous breakfast, clean room overlooking the vineyard, kind and helpful staff, lovely pool area to relax in, and three restaurants on site or within easy walking distance. Not located in town so you need to drive a few minutes to grocery stores or the museum, but perfect for a quiet relaxing stay in nature. "

[](https://expedia.com/San-Fernando-Hotels-TerraVina.h3775207.Hotel-Information)

![La Perla Hotel](https://images.trvl-media.com/lodging/19000000/18060000/18057500/18057456/afe65d1c_y.jpg)

### La Perla Hotel

10/10 Excellent

"Excellent Staff, excellent facilities, and an excellent sleep in a very quiet location."

[](https://expedia.com/San-Fernando-Hotels-La-Perla-Hotel.h18057456.Hotel-Information)

![Hotel Vendimia Parador](https://images.trvl-media.com/lodging/23000000/22440000/22438600/22438533/93f91da4_y.jpg)

### Hotel Vendimia Parador

10/10 Excellent

"Our stay was spectacular! Our host Mauricio and his family were welcoming and accommodating. It felt glorious to stroll around the grounds and pick fruit and even almonds! Our room was spacious with a private balcony, and the house was gorgeous with antique furniture and decor everywhere. This is a Must Stay! "

[](https://expedia.com/San-Fernando-Hotels-Hotel-Vendimia-Parador.h22438533.Hotel-Information)

![Hotel Boutique Solaz Bella Vista de Colchagua](https://images.trvl-media.com/lodging/5000000/4250000/4248400/4248321/d436566a_y.jpg)

### Hotel Boutique Solaz Bella Vista de Colchagua

10/10 Excellent

"The hotel was in a great location and the garden and pool made it a very relaxing place to stay. All the staff were so friendly and helpful - they had given great advice before we arrived and booked wine tours for us which made our stay all the more enjoyable! Breakfast was also really good. We would certainly stay here again. "

[](https://expedia.com/San-Fernando-Hotels-Hotel-Boutique-Solaz-Bella-Vista-De-Colchagua.h4248321.Hotel-Information)

![Casa Calfu](https://images.trvl-media.com/lodging/20000000/19900000/19897100/19897092/6f9059fe_y.jpg)

### Casa Calfu

10/10 Excellent

"This was a beautiful place to stay. Great to have the pool. The breakfast was delicious, excellent location and lovely staff. I wish we could have stayed longer but we were at the end of our travels. "

[](https://expedia.com/San-Fernando-Hotels-Casa-Calfu-Hostal-Bed-And-Breakfast.h19897092.Hotel-Information)

![Hotel Boutique Vendimia Premium](https://images.trvl-media.com/lodging/3000000/2960000/2959500/2959484/e7728f8a_y.jpg)

### Hotel Boutique Vendimia Premium

10/10 Excellent

"A comfortable, family run friendly place to stay. It's a bit quirky, and full of interesting memorabilia, but just perfect for us, with a swimming pool and a couple of excellent restaurants within 1 min walking for dinner. Spot on."

[](https://expedia.com/San-Fernando-Hotels-Hotel-Boutique-Vendimia-Premium.h2959484.Hotel-Information)

![Hotel Boutique Grand Cru](https://images.trvl-media.com/lodging/112000000/111720000/111717800/111717705/60f6a89d_y.jpg)

### Hotel Boutique Grand Cru

10/10 Excellent

"We thoroughly enjoyed our time with the great people who own and manage this hidden gem."

[](https://expedia.com/Santa-Cruz-Hotels-Hotel-Boutique-Grand-Cru.h111717705.Hotel-Information)

![Hotel Cava Colchagua](https://images.trvl-media.com/lodging/10000000/9430000/9423000/9422950/38e10dec_y.jpg)

### Hotel Cava Colchagua

10/10 Excellent

"Hermosa localidad y buen servicio. "

[](https://expedia.com/San-Fernando-Hotels-Hotel-Cava-Colchagua.h9422950.Hotel-Information)

## Find out more about Santa Cruz

**Everything you need to know about Santa Cruz vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Santa Cruz vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Cruz in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $71 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Santa Cruz rentals**

At Expedia, we put the best Santa Cruz vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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- [B&B in Santa Cruz ](https://expedia.com/Santa-Cruz-Bed-And-Breakfast.d6047957-aaBedAndBreakfast.Travel-Guide-Accommodation)
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### Expedia's Latest Trends

Hotels

- [Best Hotels in San Pedro de Atacama](https://expedia.com/San-Pedro-De-Atacama-Hotels.d500224.Travel-Guide-Hotels)
- [Rancagua Resorts & Hotels with Spas](https://expedia.com/Rancagua-Hotels-Spa-Hotel.0-0-d6085078-tSpaHotel.Travel-Guide-Filter-Hotels)
- [Pichilemu Pet-friendly Hotels](https://expedia.com/Pichilemu-Hotels-Pet-Friendly-Hotel.0-0-d6130903-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
- [Best Hotels in San Fernando](https://expedia.com/San-Fernando-Hotels.d6053655.Travel-Guide-Hotels)
- [Best Hotels in Coltauco](https://expedia.com/Coltauco-Hotels.d3000477949.Travel-Guide-Hotels)
- [Best Hotels in Vina del Mar](https://expedia.com/Vina-Del-Mar-Hotels.d6053651.Travel-Guide-Hotels)
- [San Vicente Resorts & Hotels with Spas](https://expedia.com/San-Vicente-Hotels-Spa-Hotel.0-0-d6338195-tSpaHotel.Travel-Guide-Filter-Hotels)

Flights

- [Flights to PUQ](https://expedia.com/Cheap-Flights-To-Punta-Arenas.d2904.Travel-Guide-Flights)
- [Flights to Lolol](https://expedia.com/Cheap-Flights-To-Lolol.d3000006362.Travel-Guide-Flights)

Cars

- [Car rentals in Los Angeles](https://expedia.com/Car-Rentals-In-Los-Angeles.d500226.Car-Rental-Guide)
- [Car rentals in Punta Arenas](https://expedia.com/Car-Rentals-In-Punta-Arenas.d2904.Car-Rental-Guide)
- [Car rentals in Pichilemu](https://expedia.com/Car-Rentals-In-Pichilemu.d6130903.Car-Rental-Guide)

Activities

- [Things to do in San Antonio](https://expedia.com/Things-To-Do-In-San-Antonio.d6336623.Travel-Guide-Activities)
- [Things to do in Rancagua](https://expedia.com/Things-To-Do-In-Rancagua.d6085078.Travel-Guide-Activities)
- [Things to do in Iquique](https://expedia.com/Things-To-Do-In-Iquique.d1623.Travel-Guide-Activities)
- [Things to do in Mostazal](https://expedia.com/Things-To-Do-In-Mostazal.d6340588.Travel-Guide-Activities)

Packages

- [Museo de Colchagua](https://expedia.com/Museo-De-Colchagua-Santa-Cruz.d6099456.Vacation-Attraction)
- [Navidad Vacation Packages](https://expedia.com/Navidad.d3000458771.Destination-Travel-Guides)
- [Pichilemu Vacation Packages](https://expedia.com/Pichilemu.d6130903.Destination-Travel-Guides)

General

- [Visit Chimbarongo](https://expedia.com/Chimbarongo.dx6354855)
- [Visit Marchihue](https://expedia.com/Marchihue.dx6176398)
- [Visit Pichilemu](https://expedia.com/Pichilemu.dx6130903)
- [Visit Concepción](https://expedia.com/Concepcion.dx790)
- [Visit Graneros](https://expedia.com/Graneros.dx3000445547)
- [Visit Mostazal](https://expedia.com/Mostazal.dx6340588)
- [Visit Vina del Mar](https://expedia.com/Vina-Del-Mar.dx6053651)
- [Visit Lolol](https://expedia.com/Lolol.dx3000006362)
- [Visit Los Andes](https://expedia.com/Los-Andes.dx6272982)
- [Visit Hanga Roa](https://expedia.com/Hanga-Roa.dx6053647)

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