Title: Santa Cruz Vacation Rentals from $70: Search Short-Term Rentals | Expedia.com

[Hotels in Santa Cruz](https://expedia.com/Santa-Cruz-Hotels.d6047957.Travel-Guide-Hotels)[Flights to Santa Cruz](https://expedia.com/Cheap-Flights-To-Santa-Cruz.d6047957.Travel-Guide-Flights)[Things to do in Santa Cruz](https://expedia.com/Things-To-Do-In-Santa-Cruz.d6047957.Travel-Guide-Activities)[Car Rentals in Santa Cruz](https://expedia.com/Car-Rentals-In-Santa-Cruz.d6047957.Car-Rental-Guide)[Santa Cruz Vacation Packages](https://expedia.com/Santa-Cruz.d6047957.Destination-Travel-Guides)

![Rows of vineyards, Santa Cruz, Chile](https://images.trvl-media.com/place/6047957/e58d3014-ef10-4c60-9e03-08890e2f5494.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6047957/e58d3014-ef10-4c60-9e03-08890e2f5494.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

## Check prices for these dates

In two weeks

[Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=6047957&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 15 - May 17](https://www.expedia.com/Hotel-Search?regionId=6047957&startDate=2026-05-15&endDate=2026-05-17&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Jun 12 - Jun 14](https://www.expedia.com/Hotel-Search?regionId=6047957&startDate=2026-06-12&endDate=2026-06-14&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jul 10 - Jul 12](https://www.expedia.com/Hotel-Search?regionId=6047957&startDate=2026-07-10&endDate=2026-07-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santa Cruz vacation rentals

![1 bedroom, laptop workspace, soundproofing, free WiFi](https://images.trvl-media.com/lodging/113000000/112020000/112019700/112019659/a6261078.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/113000000/112020000/112019700/112019659/0501d5fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/113000000/112020000/112019700/112019659/cc686363.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/113000000/112020000/112019700/112019659/2934ee8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabin in Santa Cruz

[](https://www.expedia.com/Santa-Cruz-Hotels-Colchagua-Tiny-Lodge.h112019659.Hotel-Information)

9.8/10

Exceptional

(8 reviews)

"Absolutely gorgeous "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jan

$201 nightly

$201 total

Mar 26 - Mar 27

[](https://www.expedia.com/Santa-Cruz-Hotels-Colchagua-Tiny-Lodge.h112019659.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/39000000/38120000/38118300/38118253/48553e33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/39000000/38120000/38118300/38118253/da1d039e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/39000000/38120000/38118300/38118253/a038bdc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/39000000/38120000/38118300/38118253/b9cfe331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Santa Cruz

[](https://www.expedia.com/Santa-Cruz-Hotels-The-Ambush-Field-And-Comfort.h38118253.Hotel-Information)

$163 nightly

$190 total

Mar 23 - Mar 24

[](https://www.expedia.com/Santa-Cruz-Hotels-The-Ambush-Field-And-Comfort.h38118253.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/94000000/93190000/93188700/93188687/db0556a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/94000000/93190000/93188700/93188687/5ff8a12e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, soap, shampoo](https://images.trvl-media.com/lodging/94000000/93190000/93188700/93188687/b6b66859.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/94000000/93190000/93188700/93188687/3f23d36b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in San Vicente de Taguatagua

[](https://www.expedia.com/San-Vicente-Hotels-Hostel-Turismo-San-Vicente-Tagua-Tagua.h93188687.Hotel-Information)

$78 nightly

$78 total

Mar 19 - Mar 20

[](https://www.expedia.com/San-Vicente-Hotels-Hostel-Turismo-San-Vicente-Tagua-Tagua.h93188687.Hotel-Information)

![Room](https://images.trvl-media.com/lodging/107000000/106960000/106959200/106959122/427ba2e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/107000000/106960000/106959200/106959122/0f55f463.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room](https://images.trvl-media.com/lodging/107000000/106960000/106959200/106959122/637baacd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/107000000/106960000/106959200/106959122/4799451f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Nancagua

[](https://www.expedia.com/Bouvet-Island-Hotels-Cozy-And-Comfortable-Tiny-Cottage.h106959122.Hotel-Information)

$75 nightly

$75 total

Mar 18 - Mar 19

[](https://www.expedia.com/Bouvet-Island-Hotels-Cozy-And-Comfortable-Tiny-Cottage.h106959122.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/120000000/119240000/119237300/119237202/b1e5a2d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/120000000/119240000/119237300/119237202/b0a32316.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/120000000/119240000/119237300/119237202/28ad04b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hair dryer, towels, soap, toilet paper](https://images.trvl-media.com/lodging/120000000/119240000/119237300/119237202/da3e2cf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cottage in Curico

[](https://www.expedia.com/Teno-Hotels-House-In-A-Natural-Setting.h119237202.Hotel-Information)

$91 nightly

$105 total

Mar 23 - Mar 24

[](https://www.expedia.com/Teno-Hotels-House-In-A-Natural-Setting.h119237202.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/121000000/120830000/120821100/120821060/64aa2b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120830000/120821100/120821060/96634182.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/121000000/120830000/120821100/120821060/689eef75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/121000000/120830000/120821100/120821060/e5b1788f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabin in Chimbarongo

[](https://www.expedia.com/Chimbarongo-Hotels-Vrbo-Property.h120821060.Hotel-Information)

$70 nightly

$70 total

Mar 26 - Mar 27

[](https://www.expedia.com/Chimbarongo-Hotels-Vrbo-Property.h120821060.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/124000000/123780000/123777400/123777358/58ef3ff1_edited_6d5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/124000000/123780000/123777400/123777358/b09f5fdb_edited_2c1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/124000000/123780000/123777400/123777358/9abb34f0_edited_f464.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/124000000/123780000/123777400/123777358/ddfe58f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Santa Cruz

[](https://www.expedia.com/Peralillo-Hotels-Beautiful-5-Bedroom-Home-Near-Santa-Cruz-Perfect-For-Your-Getaway.h123777358.Hotel-Information)

$563 nightly

$563 total

Mar 23 - Mar 24

[](https://www.expedia.com/Peralillo-Hotels-Beautiful-5-Bedroom-Home-Near-Santa-Cruz-Perfect-For-Your-Getaway.h123777358.Hotel-Information)

![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/117000000/116740000/116738800/116738795/bd08745e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/117000000/116740000/116738800/116738795/d58c976f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/117000000/116740000/116738800/116738795/cb86fe34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/117000000/116740000/116738800/116738795/dc4fbb05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in San Fernando

[](https://www.expedia.com/San-Fernando-Hotels-Vrbo-Property.h116738795.Hotel-Information)

$135 nightly

$135 total

Mar 23 - Mar 24

[](https://www.expedia.com/San-Fernando-Hotels-Vrbo-Property.h116738795.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/128000000/127210000/127208800/127208783/daed677e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/128000000/127210000/127208800/127208783/4e56be96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/128000000/127210000/127208800/127208783/a587f9e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room](https://images.trvl-media.com/lodging/128000000/127210000/127208800/127208783/b1b4a8aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Curicó

[](https://www.expedia.com/Curico-Hotels-Vrbo-Property.h127208783.Hotel-Information)

$92 nightly

$106 total

Mar 18 - Mar 19

[](https://www.expedia.com/Curico-Hotels-Vrbo-Property.h127208783.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-31&endDate=2026-04-01&regionId=6047957&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+O%27Higgins+Region%2C+Chile&regionId=6047957&latLong=-34.640343%2C-71.365997&adults=2&startDate=2026-06-15&d1=2026-06-15&endDate=2026-06-18&d2=2026-06-18&lodging=CABIN)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+O%27Higgins+Region%2C+Chile&regionId=6047957&latLong=-34.640343%2C-71.365997&adults=2&startDate=2026-06-15&d1=2026-06-15&endDate=2026-06-18&d2=2026-06-18&lodging=VACATION_HOME)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+O%27Higgins+Region%2C+Chile&regionId=6047957&latLong=-34.640343%2C-71.365997&adults=2&startDate=2026-06-15&d1=2026-06-15&endDate=2026-06-18&d2=2026-06-18&lodging=APARTMENT)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+O%27Higgins+Region%2C+Chile&regionId=6047957&latLong=-34.640343%2C-71.365997&adults=2&startDate=2026-06-15&d1=2026-06-15&endDate=2026-06-18&d2=2026-06-18&lodging=COTTAGE)

![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg)

Save an average of 15% on thousands of hotels when you're signed in

[Sign in

](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Vacation-Rentals.d6047957.Travel-Guide-VacationRentals)[

Sign up, it's free

](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Vacation-Rentals.d6047957.Travel-Guide-VacationRentals)

## Top Santa Cruz Hotel Reviews

![TerraViña](https://images.trvl-media.com/lodging/4000000/3780000/3775300/3775207/5e3744e0_y.jpg)

### TerraViña

10/10 Excellent

"The hotel had a great buffet breakfast which was included with your stay. The staff were helpful and friendly would offer to book restaurant reservations. The only complaint was we found the air conditioner fan to loud."

[](https://expedia.com/San-Fernando-Hotels-TerraVina.h3775207.Hotel-Information)

![Hotel Vendimia Parador](https://images.trvl-media.com/lodging/23000000/22440000/22438600/22438533/93f91da4_y.jpg)

### Hotel Vendimia Parador

8/10 Good

"Definitely pet friendly place, we were met with two dogs and two cats. This is a nice plantation style hotel with nice garden. The decor reminded us one of a Pablo Neruda's Isla Negra house. Great breakfast setting. "

[](https://expedia.com/San-Fernando-Hotels-Hotel-Vendimia-Parador.h22438533.Hotel-Information)

![Santa Cruz Plaza](https://images.trvl-media.com/lodging/2000000/1410000/1406700/1406642/3fe1c8d9_y.jpg)

### Santa Cruz Plaza

8/10 Good

"Mostly clean room, wonderful staff"

[](https://expedia.com/San-Fernando-Hotels-Santa-Cruz-Plaza.h1406642.Hotel-Information)

![La Perla Hotel](https://images.trvl-media.com/lodging/19000000/18060000/18057500/18057456/afe65d1c_y.jpg)

### La Perla Hotel

10/10 Excellent

"Excellent Staff, excellent facilities, and an excellent sleep in a very quiet location."

[](https://expedia.com/San-Fernando-Hotels-La-Perla-Hotel.h18057456.Hotel-Information)

![Hotel Boutique Solaz Bella Vista de Colchagua](https://images.trvl-media.com/lodging/5000000/4250000/4248400/4248321/d436566a_y.jpg)

### Hotel Boutique Solaz Bella Vista de Colchagua

10/10 Excellent

"The hotel was in a great location and the garden and pool made it a very relaxing place to stay. All the staff were so friendly and helpful - they had given great advice before we arrived and booked wine tours for us which made our stay all the more enjoyable! Breakfast was also really good. We would certainly stay here again. "

[](https://expedia.com/San-Fernando-Hotels-Hotel-Boutique-Solaz-Bella-Vista-De-Colchagua.h4248321.Hotel-Information)

![Casa Calfu](https://images.trvl-media.com/lodging/20000000/19900000/19897100/19897092/6f9059fe_y.jpg)

### Casa Calfu

10/10 Excellent

"This was a beautiful place to stay. Great to have the pool. The breakfast was delicious, excellent location and lovely staff. I wish we could have stayed longer but we were at the end of our travels. "

[](https://expedia.com/San-Fernando-Hotels-Casa-Calfu-Hostal-Bed-And-Breakfast.h19897092.Hotel-Information)

![Hotel Boutique Vendimia Premium](https://images.trvl-media.com/lodging/3000000/2960000/2959500/2959484/e7728f8a_y.jpg)

### Hotel Boutique Vendimia Premium

10/10 Excellent

"A comfortable, family run friendly place to stay. It's a bit quirky, and full of interesting memorabilia, but just perfect for us, with a swimming pool and a couple of excellent restaurants within 1 min walking for dinner. Spot on."

[](https://expedia.com/San-Fernando-Hotels-Hotel-Boutique-Vendimia-Premium.h2959484.Hotel-Information)

![Hotel Boutique Grand Cru](https://images.trvl-media.com/lodging/112000000/111720000/111717800/111717705/60f6a89d_y.jpg)

### Hotel Boutique Grand Cru

10/10 Excellent

"We thoroughly enjoyed our time with the great people who own and manage this hidden gem."

[](https://expedia.com/Santa-Cruz-Hotels-Hotel-Boutique-Grand-Cru.h111717705.Hotel-Information)

## Find out more about Santa Cruz

**Everything you need to know about Santa Cruz vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Santa Cruz vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Cruz in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $70 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Santa Cruz rentals**

At Expedia, we put the best Santa Cruz vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

- Trending destinations on Expedia.com
- All accommodation types in Santa Cruz

### Trending destinations on Expedia.com

- [Destin Vacation Rentals ](https://www.expedia.com/Destin-Vacation-Rentals.d6906.Travel-Guide-VacationRentals)
- [Panama City Vacation Rentals ](https://www.expedia.com/Panama-City-Beach-Vacation-Rentals.d8021.Travel-Guide-VacationRentals)
- [Hilton Head Vacation Rentals ](https://www.expedia.com/Hilton-Head-Island-Vacation-Rentals.d601684.Travel-Guide-VacationRentals)
- [Gulf Shores Vacation Rentals ](https://www.expedia.com/Gulf-Shores-Vacation-Rentals.d603078.Travel-Guide-VacationRentals)
- [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals)
- [Gatlinburg Vacation Rentals ](https://www.expedia.com/Gatlinburg-Vacation-Rentals.d7474.Travel-Guide-VacationRentals)
- [Maui Vacation Rentals ](https://www.expedia.com/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals)
- [Orlando Vacation Rentals ](https://www.expedia.com/Orlando-Vacation-Rentals.d178294.Travel-Guide-VacationRentals)
- [Myrtle Beach Vacation Rentals ](https://www.expedia.com/Myrtle-Beach-Vacation-Rentals.d601685.Travel-Guide-VacationRentals)
- [Orange Beach Vacation Rentals ](https://www.expedia.com/Orange-Beach-Vacation-Rentals.d9136.Travel-Guide-VacationRentals)
- [Pigeon Forge Vacation Rentals ](https://www.expedia.com/Pigeon-Forge-Vacation-Rentals.d8264.Travel-Guide-VacationRentals)
- [Ocean City Vacation Rentals ](https://www.expedia.com/Ocean-City-Vacation-Rentals.d9151.Travel-Guide-VacationRentals)
- [Outer Banks Vacation Rentals ](https://www.expedia.com/Outer-Banks-Vacation-Rentals.d602135.Travel-Guide-VacationRentals)
- [San Diego Vacation Rentals ](https://www.expedia.com/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)
- [Siesta Key Vacation Rentals ](https://www.expedia.com/Siesta-Key-Vacation-Rentals.d6881.Travel-Guide-VacationRentals)
- [Galveston Vacation Rentals ](https://www.expedia.com/Galveston-Vacation-Rentals.d1341.Travel-Guide-VacationRentals)
- [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals)
- [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals)
- [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals)
- [Lake Tahoe Vacation Rentals ](https://www.expedia.com/South-Lake-Tahoe-Vacation-Rentals.d10150.Travel-Guide-VacationRentals)
- [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals)
- [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
- [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations)
- [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations)

- [B&B in Santa Cruz ](https://expedia.com/Santa-Cruz-Bed-And-Breakfast.d6047957-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Vacation Homes in Santa Cruz ](https://expedia.com/Santa-Cruz-Private-Vacation-Homes.d6047957-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Lodges in Santa Cruz ](https://expedia.com/Santa-Cruz-Lodges.d6047957-aaLodges.Travel-Guide-Accommodation)
- [Hostels in Santa Cruz ](https://expedia.com/Santa-Cruz-Hostels.d6047957-aaHostels.Travel-Guide-Accommodation)

## Frequently asked questions

### Can I find a vacation rental in Santa Cruz?

### What's the top vacation rental that Santa Cruz has to offer?

### What can I see and do in Santa Cruz?

### What are vacation rentals like in Santa Cruz?

### Expedia's Latest Trends

Hotels

- [Best Hotels in San Pedro de Atacama](https://expedia.com/San-Pedro-De-Atacama-Hotels.d500224.Travel-Guide-Hotels)
- [Rancagua Resorts & Hotels with Spas](https://expedia.com/Rancagua-Hotels-Spa-Hotel.0-0-d6085078-tSpaHotel.Travel-Guide-Filter-Hotels)
- [Pichilemu Pet-friendly Hotels](https://expedia.com/Pichilemu-Hotels-Pet-Friendly-Hotel.0-0-d6130903-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
- [Best Hotels in San Fernando](https://expedia.com/San-Fernando-Hotels.d6053655.Travel-Guide-Hotels)
- [Best Hotels in Coltauco](https://expedia.com/Coltauco-Hotels.d3000477949.Travel-Guide-Hotels)
- [Best Hotels in Vina del Mar](https://expedia.com/Vina-Del-Mar-Hotels.d6053651.Travel-Guide-Hotels)
- [San Vicente Resorts & Hotels with Spas](https://expedia.com/San-Vicente-Hotels-Spa-Hotel.0-0-d6338195-tSpaHotel.Travel-Guide-Filter-Hotels)

Flights

- [Flights to PUQ](https://expedia.com/Cheap-Flights-To-Punta-Arenas.d2904.Travel-Guide-Flights)
- [Flights to Lolol](https://expedia.com/Cheap-Flights-To-Lolol.d3000006362.Travel-Guide-Flights)

Cars

- [Car rentals in Los Angeles](https://expedia.com/Car-Rentals-In-Los-Angeles.d500226.Car-Rental-Guide)
- [Car rentals in Punta Arenas](https://expedia.com/Car-Rentals-In-Punta-Arenas.d2904.Car-Rental-Guide)
- [Car rentals in Pichilemu](https://expedia.com/Car-Rentals-In-Pichilemu.d6130903.Car-Rental-Guide)

Activities

- [Things to do in San Antonio](https://expedia.com/Things-To-Do-In-San-Antonio.d6336623.Travel-Guide-Activities)
- [Things to do in Rancagua](https://expedia.com/Things-To-Do-In-Rancagua.d6085078.Travel-Guide-Activities)
- [Things to do in Iquique](https://expedia.com/Things-To-Do-In-Iquique.d1623.Travel-Guide-Activities)
- [Things to do in Mostazal](https://expedia.com/Things-To-Do-In-Mostazal.d6340588.Travel-Guide-Activities)

Packages

- [Museo de Colchagua](https://expedia.com/Museo-De-Colchagua-Santa-Cruz.d6099456.Vacation-Attraction)
- [Navidad Vacation Packages](https://expedia.com/Navidad.d3000458771.Destination-Travel-Guides)
- [Pichilemu Vacation Packages](https://expedia.com/Pichilemu.d6130903.Destination-Travel-Guides)

General

- [Visit Chimbarongo](https://expedia.com/Chimbarongo.dx6354855)
- [Visit Marchihue](https://expedia.com/Marchihue.dx6176398)
- [Visit Pichilemu](https://expedia.com/Pichilemu.dx6130903)
- [Visit Concepción](https://expedia.com/Concepcion.dx790)
- [Visit Graneros](https://expedia.com/Graneros.dx3000445547)
- [Visit Mostazal](https://expedia.com/Mostazal.dx6340588)
- [Visit Vina del Mar](https://expedia.com/Vina-Del-Mar.dx6053651)
- [Visit Lolol](https://expedia.com/Lolol.dx3000006362)
- [Visit Los Andes](https://expedia.com/Los-Andes.dx6272982)
- [Visit Hanga Roa](https://expedia.com/Hanga-Roa.dx6053647)