Santa Isabel do Rio Negro Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Discover the most popular places to visit in Santa Isabel do Rio Negro

Santa Isabel do Rio Negro Hotel Deals

Rede Andrade Amazônia

Rede Andrade Amazônia

3 out of 5
Av. Getúlio Vargas 227 Manaus AM
Fully refundableReserve now, pay when you stay
$29 nightly
The price is $29 total per night from Apr 26 to Apr 27
$29 total
Apr 26 - Apr 27
Total with taxes and fees
8/10 Very Good! (967 reviews)
If you need Wifi ,- forget it! Drops out even in lobby. So frustrating.

Reviewed on Mar 11, 2026

Rede Andrade Amazônia
Hotel Intercity Manaus

Hotel Intercity Manaus

4 out of 5
Rua Professor Marciano Armond, 544 Manaus AM
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $71 total per night from Apr 11 to Apr 12
$71 total
Apr 11 - Apr 12
Total with taxes and fees
8.4/10 Very Good! (960 reviews)
We were greeted by a well spoken young man that spoke excellent English which was very well received! Super helpful and rooms were small but just what we needed for our purposes. Very clean and buffet breakfast had something for everyone! Very helpful with the little store where we could purchase ...

Reviewed on Apr 2, 2026

Hotel Intercity Manaus
Hotel Express Vieiralves

Hotel Express Vieiralves

3 out of 5
Rua Rio Branco, s/n Manaus AM
Fully refundableReserve now, pay when you stay
$36 nightly
The price is $37 total per night from May 10 to May 11
$37 total
May 10 - May 11
Total with taxes and fees
Hotel Express Vieiralves
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Isabel do Rio Negro Vacation Packages

Santa Isabel do Rio Negro Essential Information

Language
Portuguese
Currency
Brazilian reals
Local Welcome
Olá
Local Goodbye
Adeus

More vacations you might like

Frequently asked questions

How much does a Santa Isabel do Rio Negro vacation package cost?
Offering great value package deals on Expedia, you'll be thrilled with how little a vacation to Santa Isabel do Rio Negro costs! Expedia's packages make travel planning easier and save you more.
What are the cheapest months to go to Santa Isabel do Rio Negro?
You can typically find lower rates and greater availability in February, March and April. Take a look at our cheap Santa Isabel do Rio Negro vacation packages and you could get some excellent off-season deals.
How many days is enough for Santa Isabel do Rio Negro?
With a well-planned schedule, you can easily hit the most popular Santa Isabel do Rio Negro attractions in a handful of days. But if you'd like to venture off the beaten track or take day trips, think about booking your Santa Isabel do Rio Negro vacation for longer.
How to find the best Santa Isabel do Rio Negro package deals?
Use Expedia's handy filters to find some unbeatable Santa Isabel do Rio Negro package deals. When you start your search, just set your maximum budget and then order the results by "Price: low to high." If you want to save, plan your break for midweek, or look for Santa Isabel do Rio Negro package deals in the low season. Play around with your travel dates and you may land even bigger discounts. As a rule of thumb, it's typically best to lock in your vacation package well in advance.
Is it cheaper to book a Santa Isabel do Rio Negro vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your hotel, flight and car rental into one great-value price and you could save hundreds of dollars. You'll generally get a better deal than booking each component individually. And you'll still enjoy the flexibility to create a customized Santa Isabel do Rio Negro vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to Santa Isabel do Rio Negro?
If you've got your Santa Isabel do Rio Negro travel dates confirmed, book as soon as you can to snap up some awesome deals. With Expedia, you can generally reserve some flights up to one year ahead of time. Prefer spontaneous trips? Our last-minute deals are perfect for quick escapes.
Does Expedia offer Book Now, Pay Later Santa Isabel do Rio Negro vacation packages?
Secure your dream getaway to Santa Isabel do Rio Negro with Expedia's Book Now, Pay Later vacations. There's no need to scrimp and save or wait for your next payday — we've partnered with online lender Affirm to give you flexibility and choice. Our vacation packages with payment plans let you spread the cost across 3, 6 or 12 months. With no late payment fees or hidden charges, it's easy to budget for your trip and snag great deals while they last.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.