Santa María Vacations from $238

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Your Santa María Vacation

Your next great adventure is just around the corner with a vacation package to Santa María. Food, fun and nothing but good times — you're sure to find it in this neighborhood. When it's time to see the sights, you'll find a lot of big-name attractions nearby including Zocalo Square, Church of Santo Domingo de Guzman and Auditorio Guelaguetza. Visit one or all during your trip to Santa María. Expedia is here to put your travel plans into action. Book your ultimate Santa María vacation today.

The Latest Santa María Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Angel Inn

Hotel Angel Inn

3.5 out of 5
San Felipe del Agua
Price was $369, price is now $238 per person
$238
per person
Feb 1 - Feb 3
found 6 hours ago
Roundtrip flight included
Mexico City (MEX) to Oaxaca Intl. (OAX)
8.6/10 Excellent! (112 reviews)
Nice looking property in what looked to be an interesting part of Oaxaca. Room was spacious, clean and complex was the same. Bed was too hard for me, but I realize many like that. I will stay there tambien!

Reviewed on Sep 3, 2024

Pug Seal Oaxaca

Pug Seal Oaxaca

3 out of 5
Oaxaca Centro
Save 100% on your flight
Price was $1,445, price is now $851 per person
$851
per person
Feb 22 - Feb 27
found 1 day ago
Roundtrip non-stop flight included
Tijuana (TIJ) to Oaxaca Intl. (OAX)
9.6/10 Exceptional! (94 reviews)
Staff was very professional and helpful. The room, in fact the entire hotel is a work of art.

Reviewed on Nov 30, 2025

Hotel Oaxaca Dorado

Hotel Oaxaca Dorado

3 out of 5
Calzada Madero
Price was $518, price is now $326 per person
$326
per person
Feb 19 - Feb 23
found 10 hours ago
Roundtrip flight included
Tijuana (TIJ) to Oaxaca Intl. (OAX)
6.6/10 (25 reviews)
Nice swimming pool,small restaurant. This place is conveniently located in El Centro walkable distances to: Plaza de la danza, La Alameda,El Zócalo,etc.

Reviewed on Oct 16, 2023

Quinta Real Oaxaca

Quinta Real Oaxaca

4.5 out of 5
Oaxaca Centro
Save 100% on your flight
Price was $1,380, price is now $883 per person
$883
per person
Feb 22 - Feb 27
found 1 day ago
Roundtrip non-stop flight included
Tijuana (TIJ) to Oaxaca Intl. (OAX)
9.6/10 Exceptional! (1,000 reviews)
Close to everything

Reviewed on Dec 12, 2025

Casa Olié

Casa Olié

3.5 out of 5
Oaxaca Centro
Save 100% on your flight
Price was $525, price is now $342 per person
$342
per person
Feb 1 - Feb 3
found 6 hours ago
Roundtrip flight included
Mexico City (MEX) to Oaxaca Intl. (OAX)
9.6/10 Exceptional! (75 reviews)
The house is beautiful, clean rooms, friendly staff and a pretty view of the street. The bed was a little bit uncomfortable, but other than that, it is a nice place to stay.

Reviewed on Oct 28, 2025

Where to stay in Santa María

Find the best Santa María areas and neighborhoods for the activities you enjoy most. Learn more about Santa María
Oaxaca which includes a city

Oaxaca Centro

8 out of top 10 points of interest in this area
4.5/5(695 area reviews)

Discover colonial-era structures and immerse in native Zapotec and Mixtec cultures in this UNESCO World Heritage Site. Explore the archeological marvel of Monte Albán and admire the unique green stone architecture.

Find hotels in Oaxaca Centro

Santa María Hotel Deals

Hotel Hacienda

Hotel Hacienda

3.5 out of 5
Av Eduardo Mata 1918 Oaxaca OAX
$51 nightly
The price is $61 total per night from Dec 14 to Dec 15
$61 total
Dec 14 - Dec 15
Total with taxes and fees
8.8/10 Excellent! (1,006 reviews)
solid location

Reviewed on Dec 9, 2025

Hotel Hacienda
Hotel Victoria Oaxaca

Hotel Victoria Oaxaca

3.5 out of 5
International Road Km 545 Oaxaca OAX
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $70 total per night from Dec 15 to Dec 16
$70 total
Dec 15 - Dec 16
Total with taxes and fees
8.6/10 Excellent! (1,000 reviews)
The hotel is a little bit outdated.The facility is limited. The area is not easy to walk.

Reviewed on Dec 1, 2025

Hotel Victoria Oaxaca
Grand Fiesta Americana Oaxaca

Grand Fiesta Americana Oaxaca

5 out of 5
Jose Maria Pino Suarez 702 Oaxaca OAX
$217 nightly
The price is $258 total per night from Dec 15 to Dec 16
$258 total
Dec 15 - Dec 16
Total with taxes and fees
9.6/10 Exceptional! (665 reviews)
Fabulous hotel. Expensive but worth it - staff were fantastic and really helpful organising anything we needed, room was very high spec, breakfast was excellent with an amazing number of options albeit it was expensive. Location was perfect - really close to the historic centre which was a short ...

Reviewed on Nov 16, 2025

Grand Fiesta Americana Oaxaca
See all 849 properties in Santa María
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Santa María

Zócalo

Zócalo

4.5/5(369 reviews)

You can learn about the history of Oaxaca with a trip to Zócalo. Make time for the shops and local tours in this culturally rich area.

Zócalo
Oaxaca

Church of Santo Domingo de Guzmán

5/5(286 reviews)

Church of Santo Domingo de Guzmán is just one of the places to see in Oaxaca, so why not enjoy the other things to explore during your travels? While in this culturally rich area, find time to visit its shops.

Church of Santo Domingo de Guzmán
Monte Albán

Monte Albán

5/5(294 reviews)

Learn about the local history of Oaxaca with a stop at Monte Albán. Make time for the shops and local tours in this culturally rich area.

Monte Albán

Things to do

Bike tour to the Tule Tree and the Gastronomic Market

Bike tour to the Tule Tree and the Gastronomic Market

$29
per adult
Bike tour to the Tule Tree and the Gastronomic Market
Oaxaca de Juarez: Monte Alban Half-Day Tour

Oaxaca de Juarez: Monte Alban Half-Day Tour

$29
per adult
100% of travellers recommend
Oaxaca de Juarez: Monte Alban Half-Day Tour
Monte Albán Oaxaca

Full-Day Monte Alban Archaeological Site and Oaxaca Artisan Experience

$50
per adult
Full-Day Monte Alban Archaeological Site and Oaxaca Artisan Experience
See all activities in Oaxaca
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.