Santa Rosa Vacations from $976

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    Save up to $2,000 when you book a flight and hotel together*
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The Latest Santa Rosa Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Jan 18 - Jan 24

    Riande Aeropuerto Hotel & Casino + Flight

    Tocumen Airport
    6 nights
    4.0 star property
    8.6/10 - Excellent (1,813 reviews)
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    $1,553
    $976
    per traveler
    found 1 day ago
    Riande Aeropuerto Hotel & Casino
  • Jan 18 - Jan 24

    Megapolis Hotel Panamá + Flight

    San Francisco
    6 nights
    4.5 star property
    8.6/10 - Excellent (1,839 reviews)
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    $2,696
    $1,209
    per traveler
    found 1 day ago
    Megapolis Hotel Panamá
  • Dec 11 - Dec 16

    Central Hotel Panama Casco Viejo + Flight

    Casco Viejo
    5 nights
    4.0 star property
    9.2/10 - Wonderful (1,001 reviews)
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    Save 100% on your flight
    $2,529
    $1,277
    per traveler
    found 2 days ago
    Central Hotel Panama Casco Viejo
  • Dec 5 - Dec 11

    Hyatt Regency Panama City + Flight

    Bella Vista
    6 nights
    5.0 star property
    9.6/10 - Exceptional (498 reviews)
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    $2,001
    $1,342
    per traveler
    found 1 day ago
    Hyatt Regency Panama City
  • Jan 18 - Jan 24

    Hotel Riu Plaza Panama + Flight

    Bella Vista
    6 nights
    5.0 star property
    9.0/10 - Wonderful (6,174 reviews)
    "El precio el servicio en todo .la limpieza en el cuarto el bufet los trabajadores fue una experiencia muy agradable muy amable todo el personal MUCHAS GRACIAS"
    Reviewed November 5, 2026
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    $1,551
    $1,053
    per traveler
    found 1 day ago
    Hotel Riu Plaza Panama

Santa Rosa Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently Asked Questions

How to find the best Santa Rosa package deals?

Use Expedia's filter tool to find some terrific Santa Rosa package deals. When you begin your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your adventure for midweek, or look for Santa Rosa package deals in the off-season. Switch up your travel dates and you may score even better discounts. As a rule of thumb, it's usually best to book your vacation package well in advance.

When to book a vacation package to Santa Rosa?

If you're considering a spontaneous Santa Rosa adventure, check out our last-minute deals that can be booked up to one week before you go. Prefer not to wait until the last minute? You can land awesome deals on your flights and hotels by booking ahead.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.