Cheap American Airlines flights Mexico City (MEX) to Pisa (PSA)

Use the "Price (lowest to highest)" filter on Expedia to search for cheap American Airlines return flights from MEX to PSA. Affordable one-way fares are available as well.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for American Airlines flights from MEX to PSA about one month before you want to leave. The cheapest time to book an international flight is generally 18 to 29 days ahead of your departure date when you can save 17% versus booking four to five months in advance. Regardless of fare class or itinerary, the best day to book international airfare is usually Sunday. Friday can be the most expensive. Passengers booking on a Sunday can save an average of 17% compared to those who book on a Friday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departures from MEX to PSA with American Airlines, filter your search by "Early Morning" and "Morning." Choosing an early flight generally means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.