Flights to Columbus from Biloxi - $58

View $58 flight on Mon, Oct 27, 2025Opens in a new window

Popular airlines from Biloxi to Columbus

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Cheap Flights from Biloxi to Columbus (MOB-CMH)

Prices were available within the past 7 days and start at $58 for one-way flights and $116 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Fri, Oct 31 - Mon, Nov 3
MSY
New Orleans
CMH
Columbus
$116 Roundtrip, found 4 hours ago
$116
Roundtrip
found 4 hours ago
Select Spirit Airlines flight, departing Fri, Oct 31 from New Orleans to Columbus, returning Mon, Nov 3, priced at $116 found 4 hours ago
Spirit Airlines
Fri, Oct 31 - Mon, Nov 3
MSY
New Orleans
CMH
Columbus
$154 Roundtrip, found 4 hours ago
$154
Roundtrip
found 4 hours ago
Select Spirit Airlines flight, departing Fri, Oct 31 from New Orleans to Columbus, returning Mon, Nov 3, priced at $154 found 4 hours ago
Southwest Airlines
Sat, Nov 1 - Mon, Nov 10
MSY
New Orleans
CMH
Columbus
$158 Roundtrip, found 12 hours ago
$158
Roundtrip
found 12 hours ago
Select Southwest Airlines flight, departing Sat, Nov 1 from New Orleans to Columbus, returning Mon, Nov 10, priced at $158 found 12 hours ago
American Airlines
Sat, Nov 1 - Mon, Nov 10
MSY
New Orleans
CMH
Columbus
$187 Roundtrip, found 12 hours ago
$187
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sat, Nov 1 from New Orleans to Columbus, returning Mon, Nov 10, priced at $187 found 12 hours ago
Delta
Fri, Oct 3 - Mon, Oct 6
MSY
New Orleans
CMH
Columbus
$217 Roundtrip, found 1 hour ago
$217
Roundtrip
found 1 hour ago
Select Delta flight, departing Fri, Oct 3 from New Orleans to Columbus, returning Mon, Oct 6, priced at $217 found 1 hour ago
Frontier Airlines
Sun, Aug 3 - Sat, Aug 23
MSY
New Orleans
CMH
Columbus
$232 Roundtrip, found 18 hours ago
$232
Roundtrip
found 18 hours ago
Select Frontier Airlines flight, departing Sun, Aug 3 from New Orleans to Columbus, returning Sat, Aug 23, priced at $232 found 18 hours ago

Find the cheapest month to fly from New Orleans (MSY) to Columbus (CMH)

March is typically the cheapest month to fly

From $68 - $290 per traveler.

Graph displaying average flight prices per month

*Available to One Key members.