$725 Cheap Flights from Cairo (CAI) to Medellín (MDE)

View $725 flight on Sun, Nov 23, 2025Opens in a new window

Popular airlines from Cairo Intl. Airport (CAI) to Jose Maria Cordova Intl. Airport (MDE)

    notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
    deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
    trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Cairo to Medellín (CAI-MDE)

Prices were available within the past 7 days and start at $725 for one-way flights and $1,208 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Lufthansa
Tue, May 19 - Tue, May 26
CAI
Cairo
MDE
Medellin
$1,208 Roundtrip, found 6 days ago
$1,208
Roundtrip
found 6 days ago
Select Lufthansa flight, departing Tue, May 19 from Cairo to Medellin, returning Tue, May 26, priced at $1,208 found 6 days ago
British Airways
Sat, Jan 17 - Sat, Jan 31
CAI
Cairo
MDE
Medellin
$1,311 Roundtrip, found 3 days ago
$1,311
Roundtrip
found 3 days ago
Select British Airways flight, departing Sat, Jan 17 from Cairo to Medellin, returning Sat, Jan 31, priced at $1,311 found 3 days ago
British Airways
Sat, Jan 17 - Sat, Jan 31
CAI
Cairo
MDE
Medellin
$1,357 Roundtrip, found 3 days ago
$1,357
Roundtrip
found 3 days ago
Select British Airways flight, departing Sat, Jan 17 from Cairo to Medellin, returning Sat, Jan 31, priced at $1,357 found 3 days ago
EGYPTAIR
Sat, May 9 - Sat, May 16
CAI
Cairo
MDE
Medellin
$1,363 Roundtrip, found 6 days ago
$1,363
Roundtrip
found 6 days ago
Select EGYPTAIR flight, departing Sat, May 9 from Cairo to Medellin, returning Sat, May 16, priced at $1,363 found 6 days ago
American Airlines
Sat, May 23 - Sat, Jun 6
CAI
Cairo
MDE
Medellin
$1,402 Roundtrip, found 11 hours ago
$1,402
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Sat, May 23 from Cairo to Medellin, returning Sat, Jun 6, priced at $1,402 found 11 hours ago
British Airways
Sat, Jan 17 - Sat, Jan 31
CAI
Cairo
MDE
Medellin
$1,406 Roundtrip, found 3 days ago
$1,406
Roundtrip
found 3 days ago
Select British Airways flight, departing Sat, Jan 17 from Cairo to Medellin, returning Sat, Jan 31, priced at $1,406 found 3 days ago
British Airways
Sat, Jan 17 - Sat, Jan 31
CAI
Cairo
MDE
Medellin
$1,421 Roundtrip, found 3 days ago
$1,421
Roundtrip
found 3 days ago
Select British Airways flight, departing Sat, Jan 17 from Cairo to Medellin, returning Sat, Jan 31, priced at $1,421 found 3 days ago
American Airlines
Sat, May 23 - Sat, Jun 6
CAI
Cairo
MDE
Medellin
$1,427 Roundtrip, found 11 hours ago
$1,427
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Sat, May 23 from Cairo to Medellin, returning Sat, Jun 6, priced at $1,427 found 11 hours ago
EGYPTAIR
Sat, May 9 - Sat, May 16
CAI
Cairo
MDE
Medellin
$1,439 Roundtrip, found 6 days ago
$1,439
Roundtrip
found 6 days ago
Select EGYPTAIR flight, departing Sat, May 9 from Cairo to Medellin, returning Sat, May 16, priced at $1,439 found 6 days ago
Iberia
Sat, May 23 - Sat, Jun 6
CAI
Cairo
MDE
Medellin
$1,476 Roundtrip, found 11 hours ago
$1,476
Roundtrip
found 11 hours ago
Select Iberia flight, departing Sat, May 23 from Cairo to Medellin, returning Sat, Jun 6, priced at $1,476 found 11 hours ago
Flights from Cairo (CAI) to Medellín (MDE)
Origin airport
Cairo Intl.
Destination airport
José María Córdova Intl.
Airlines serving
American Airlines, Iberia, United
Roundtrip price
$1,208
Distance
6995 mi

Cairo to Medellín Flights

The cheapest times to fly from Cairo to Medellín

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cairo to Medellín are during the month of May. You can find some of the cheapest flights from Cairo to Medellín with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Cairo to Medellín

Sunday is one of the best days to book for cheap flights from Cairo to Medellín: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Cairo to Medellín

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cairo to Medellín in 2025. You can also book with separate airlines for your outbound and return journeys, from $725 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cairo to Medellín flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cairo to Medellín airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Cairo Intl. Airport (CAI) to Jose Maria Cordova Intl. Airport (MDE) cost?
Lock in a cheap one-way flight from $725 or cheap return flight from $1,208 from Cairo Intl. Airport (CAI) to Jose Maria Cordova Intl. Airport (MDE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Cairo Intl. Airport (CAI) to Jose Maria Cordova Intl. Airport (MDE)?
Traveling in May is a great way to save, as it's the cheapest month for flights between CAI and MDE. You'll often find the lowest fares during the off-season.
What is the cheapest airline that flies from Cairo Intl. Airport (CAI) to Jose Maria Cordova Intl. Airport (MDE)?
To find the cheapest airline that'll fly you from CAI to MDE, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and number of stops. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Cairo Intl. Airport (CAI) to Jose Maria Cordova Intl. Airport (MDE)?
Nonstop flights from Cairo Intl. Airport (CAI) to Jose Maria Cordova Intl. Airport (MDE) aren't available daily, so you'll have to take a flight with a layover. Explore your options with our filter tool. Enter your dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from CAI to MDE?
Typically you'll have the most choice when it comes to flights on a Friday. Tuesdays tend to be the quietest.* But this can change based on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Cairo Intl. Airport (CAI) to Jose Maria Cordova Intl. Airport (MDE)?
To avoid potential delays on the Cairo Intl. Airport (CAI) to Jose Maria Cordova Intl. Airport (MDE) route, aim to travel before 3 PM. Flights after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Cairo Intl. Airport (CAI) to Jose Maria Cordova Intl. Airport (MDE) last-minute?
Waiting until right before your break to book a flight from CAI to MDE generally means paying more. While it's possible to find some last-minute deals, they're not always guaranteed. Be flexible with your travel plans for a better chance of scoring a bargain.
Is it cheaper to book a CAI to MDE flight and hotel package?
Compared with arranging flights and hotels separately, booking a CAI to MDE flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one easy place takes the hassle out of planning your trip. Just pick your flights and select from our extensive range of stays, then personalize your trip with extras like tours, car rentals and activities.
Can I cancel or change the date of my flight from Cairo Intl. Airport (CAI) to Jose Maria Cordova Intl. Airport (MDE)?
If you reserved your CAI to MDE flight in the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more details.

Explore a world of travel with Expedia

*Available to One Key members.