$68 Cheap Flights from Buenos Aires (EZE) to Santiago del Estero (SDE)

View $68 flight on Thu, Nov 6, 2025Opens in a new window

Popular airlines from Ministro Pistarini Intl. Airport (EZE) to Santiago del Estero (SDE-Vicecomodoro Angel de la Paz Aragones)

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Cheap Flights from Buenos Aires to Santiago del Estero (EZE-SDE)

Prices were available within the past 7 days and start at $68 for one-way flights and $271 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aerolineas Argentinas
Fri, Jan 16 - Sun, Feb 8
EZE
Buenos Aires
SDE
Santiago del Estero
$271 Roundtrip, found 5 days ago
$271
Roundtrip
found 5 days ago
Select Aerolineas Argentinas flight, departing Fri, Jan 16 from Buenos Aires to Santiago del Estero, returning Sun, Feb 8, priced at $271 found 5 days ago
Aerolineas Argentinas
Fri, Jan 16 - Sun, Feb 8
EZE
Buenos Aires
SDE
Santiago del Estero
$296 Roundtrip, found 5 days ago
$296
Roundtrip
found 5 days ago
Select Aerolineas Argentinas flight, departing Fri, Jan 16 from Buenos Aires to Santiago del Estero, returning Sun, Feb 8, priced at $296 found 5 days ago
Aerolineas Argentinas
Fri, Jan 16 - Sun, Feb 8
EZE
Buenos Aires
SDE
Santiago del Estero
$326 Roundtrip, found 5 days ago
$326
Roundtrip
found 5 days ago
Select Aerolineas Argentinas flight, departing Fri, Jan 16 from Buenos Aires to Santiago del Estero, returning Sun, Feb 8, priced at $326 found 5 days ago

Frequently asked questions

How much does a flight from Ministro Pistarini Intl. Airport (EZE) to Vicecomodoro Angel de la Paz Aragones Airport (SDE) cost?
Lock in a cheap one-way flight from $68 or cheap return flight from $271 from Ministro Pistarini Intl. Airport (EZE) to Vicecomodoro Angel de la Paz Aragones Airport (SDE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Ministro Pistarini Intl. Airport (EZE) to Vicecomodoro Angel de la Paz Aragones Airport (SDE)?
The cheapest month to fly from EZE to SDE is January, when demand is low. Off-peak season is typically when you'll find lower airfares between these airports.
Which airlines fly direct from Ministro Pistarini Intl. Airport (EZE) to Vicecomodoro Angel de la Paz Aragones Airport (SDE)?
Direct flights aren't available from Buenos Aires (EZE-Ministro Pistarini Intl.) to Vicecomodoro Angel de la Paz Aragones Airport (SDE). However, you can find other airports that offer nonstop flights. Board your plane at Aeroparque Jorge Newbery Airport (AEP) and head straight to Santiago del Estero without a layover.
What is the cheapest airline that flies from Ministro Pistarini Intl. Airport (EZE) to Vicecomodoro Angel de la Paz Aragones Airport (SDE)?
Use the filters on Expedia to compare different airlines and find the cheapest carrier that'll take you from EZE to SDE. Then, sort your results by "Price (lowest to highest)" to score a good deal.
How many flights per day from Ministro Pistarini Intl. Airport (EZE) to Vicecomodoro Angel de la Paz Aragones Airport (SDE)?
There are no daily direct flights departing from Ministro Pistarini Intl. Airport (EZE) to Vicecomodoro Angel de la Paz Aragones Airport (SDE). But you can book flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be cruising above the clouds in no time at all.
What day of the week has the most flights from EZE to SDE?
Usually you'll find the greatest selection of flight options on a Friday. Tuesdays tend to be the quietest.* However, this can vary depending on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Ministro Pistarini Intl. Airport (EZE) to Vicecomodoro Angel de la Paz Aragones Airport (SDE)?
Book a flight from Ministro Pistarini Intl. Airport (EZE) to Vicecomodoro Angel de la Paz Aragones Airport (SDE) that takes off before 3 PM to reduce the likelihood of delays and cancellations. Departures after this hour have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Ministro Pistarini Intl. Airport (EZE) to Vicecomodoro Angel de la Paz Aragones Airport (SDE) last-minute?
Booking your plane ticket from EZE to SDE right before your getaway is generally more expensive. But if you're flexible with your departure times and dates, you could land a cheap last-minute fare.
Is it cheaper to book an EZE to SDE flight and hotel package?
You'll typically save money by booking an EZE to SDE flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. After selecting your ideal accommodations and flights, consider adding extras including tours, activities and car rentals.
Can I cancel or change the date of my flight from Ministro Pistarini Intl. Airport (EZE) to Vicecomodoro Angel de la Paz Aragones Airport (SDE)?
It's usually possible to cancel or reschedule your EZE to SDE flight. However, for bookings made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
Ministro Pistarini Intl.
Destination airport
Vicecomodoro Angel de la Paz Aragones
Roundtrip price
$270
Distance
594 mi
Average flight time
1 hour 50 mins

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Buenos Aires to Santiago del Estero Flights

The cheapest times to fly from Buenos Aires to Santiago del Estero

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Buenos Aires to Santiago del Estero are during the month of January. You can find some of the cheapest flights from Buenos Aires to Santiago del Estero with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Buenos Aires to Santiago del Estero

Sunday is one of the best days to book for cheap flights from Buenos Aires to Santiago del Estero: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Buenos Aires to Santiago del Estero

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Buenos Aires to Santiago del Estero in 2025. You can also book with separate airlines for your outbound and return journeys, from $68 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Buenos Aires to Santiago del Estero flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Buenos Aires to Santiago del Estero airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Buenos Aires to Santiago del Estero Flights

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*Available to One Key members.