$435 Cheap Flights from Phoenix (PHX) to Santiago (SCL)

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Phoenix (PHX) to Santiago (SCL) at a glance

Embark on an international long-haul journey from Phoenix (PHX) to Santiago (SCL) with a selection of airlines offering diverse routes. Explore flight options from full-service carriers to discover the itinerary that aligns with your budget, schedule, and travel aspirations while immersing yourself in Santiago's renowned attractions and neighborhoods. Here, you'll find essential information for flights departing from Sky Harbor International Airport (PHX) to Arturo Merino Benitez Airport (SCL).

• Fastest flight duration: around 12h 30m in-flight, plus roughly 2 hours layover with one stop
• Route distance: roughly 5,300 miles (8,530 km)
• Flights per week: around 8 departures on average
• Typical fares (one-way): economy tickets often range from $380–$1005, depending on seasonality and how far ahead you book

Flights from Sky Harbor International Airport (PHX) to Arturo Merino Benitez Airport (SCL)

According to the latest traveler bookings, here are the top airlines favored for flights from Phoenix to Santiago, particularly for one-stop and multi-stop journeys. Common layover points include Miami International Airport (MIA), with an approximate layover of 2 hours and 30 minutes; Dallas-Fort Worth International Airport (DFW), offering about 1 hour and 15 minutes; and Hartsfield-Jackson Atlanta International Airport (ATL), with a layover of around 1 hour and 45 minutes. This gives you the chance to customize your itinerary based on price, total travel time, and cabin class.

• American Airlines: This comprehensive carrier provides one-stop travel options, with one-way ticket prices generally falling between $380 and $1005. It is responsible for about 50% of the departures on this route, featuring a flight duration of 12 hours and 30 minutes, and a total travel time of approximately 14 hours and 45 minutes, including layovers.
• Delta: As a full-service airline, Delta offers one-stop routes with one-way fares typically priced from $405 to $765. It makes up around 31% of the departures on this route, with an in-flight duration of 12 hours and 30 minutes, leading to a total journey time of about 14 hours and 45 minutes, inclusive of layovers.
• United: Another full-service airline, United provides one-stop service with one-way fares that usually range from $420 to $1205. It accounts for roughly 9% of the departures on this route, featuring an in-flight time of 12 hours and 30 minutes and a total journey time of around 14 hours and 45 minutes, factoring in layovers.
• LATAM Airlines Group: This full-service carrier offers one-stop services, with one-way fares typically between $540 and $1025. It comprises about 6% of the departures along this route, with a flight duration of 12 hours and 30 minutes and a total travel time of roughly 14 hours and 45 minutes, including layover periods.
• Copa: Operating with a multi-stop service, Copa presents one-way fares generally between $480 and $720. This airline covers approximately 3% of the route's departures, with an in-flight time of 14 hours and 15 minutes, leading to an overall journey time of nearly 19 hours, taking into account layovers.

Best time to fly from Phoenix (PHX) to Santiago (SCL)

The most popular months for travelers flying from Phoenix to Santiago are January, February, and March, when peak temperatures in Santiago reach up to 68°F in January. If you prefer quieter travel, consider August, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 48°F. For better deals, October usually offers the lowest average one-way fare around $536. Flight availability peaks in December, with approximately 9 flights per week, making it easier to find convenient departure times.

• Cheapest time to fly: October usually offers good deals with average one-way fare around $536, roughly 13% cheaper than the yearly average.
• More budget-friendly months to fly: November, August, and February typically offer average one-way fares roughly ranging from $538 to $569.
• Most flight options: December has the highest number of flights from Phoenix to Santiago, with approximately 9 flights per week, giving you more flexibility in scheduling your trip.

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

How to find the best prices for flights from Phoenix (PHX) to Santiago (SCL)

Getting some of the best deals on flights from Phoenix to Santiago is all about timing and flexibility. Here are some key tips to help you save:

1. Best times to book and fly: cheaper fares are usually available when booking 2-8 weeks in advance, although most travelers tend to book at least 2 months ahead. Additionally, afternoon departures between 12 PM and 6 PM often provide lower prices and are the most popular times to fly. Flying on Wednesday generally offers cheaper rates, while Monday is the most favored travel day.
2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Arturo Merino Benitez Airport from Sky Harbor International Airport

Santiago welcomes travelers from Phoenix with a range of transport options based on price, convenience, and proximity. Here's how to reach Santiago efficiently:

• Hotel transfer: Transfers offer a convenient way to reach your hotel in Santiago, with private rides that can be arranged in advance.
• Car rental: Renting a car from Arturo Merino Benitez Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Arturo Merino Benitez Airport on Expedia.
• Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
• Public transportation: From Arturo Merino Benitez Airport, Barrancas Station (a metro station) is located about 6.6 miles away by car, while Lo Cruzat Metro Station (a train station) is situated approximately 8.3 miles from the airport, also accessible by car.

Phoenix to Santiago Flights

The cheapest times to fly from Phoenix to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Phoenix to Santiago are during the month of January. You can find some of the cheapest flights from Phoenix to Santiago with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Phoenix to Santiago

Sunday is one of the best days to book for cheap flights from Phoenix to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Phoenix to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Phoenix to Santiago in 2026. You can also book with separate airlines for your outbound and return journeys, from $435 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Phoenix to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Phoenix to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently Asked Questions

How much does a flight from Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez) cost?

You can find cheap one-way flights from $435 and cheap return flights $881 Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez) with Expedia. One-way flights usually range from $542 to $2043, and return flights typically cost between $866 and $3148. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez) ticket fares go up or down.

*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.

What is the cheapest month to fly from Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez)?

The cheapest month to fly from PHX to SCL is January when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.

Which airlines fly direct from Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez)?

Enter PHX to SCL and your travel dates, then apply the 'Nonstop' filter to see only direct flights.

What is the cheapest airline that flies from Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez)?

Avianca is one of the cheapest airlines offering connecting flights from Phoenix, AZ (PHX) to Santiago (SCL), with round-trip tickets starting from around $1187 with a layover in Washington Dulles (IAD). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.

*Prices based on flights available on Expedia in the last year.

How do I find cheap flights from Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez)?

To find a cheap flight from Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.

What is the best time to fly from Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez)?

The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.

What is the earliest flight from Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez)?

The earliest flight from Sky Harbor International Airport (PHX) to Arturo Merino Benitez Airport (SCL) typically departs at 12:25 AM, operated by United and Copa Airlines. This seasonal service is active in December, allowing you to arrive in Santiago early and make the most of your day. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.

What are the most popular departure times for flights from Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez)?

The most popular departure times for flights from Phoenix, AZ (PHX) to Santiago (SCL) are in the early afternoon, from 12pm to 3pm. About 35% of passengers prefer this time window. Many major carriers, including American Airlines, Delta, and United Airlines, offer flights during this window. This timing works well because it allows you to enjoy a leisurely morning before heading to the airport.

How long does it take to fly from Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez)?

Flying from PHX to SCL with a connection usually takes about 18 hours 20 minutes, traveling roughly 5,337 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.

Can you fly business or first class from Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez)?

You can fly business class between PHX and SCL. Airlines that offer business class service on this route include:

• United Airlines
• Air Canada
• Delta Air Lines
• American Airlines
• British Airways
• LATAM Airlines
• Aeromexico

How do I earn miles on a Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez) flight with Expedia?

It's easy to earn miles on a Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

What airports do you fly into for Santiago from Sky Harbor Intl. (PHX)?

When traveling from Sky Harbor Intl. (PHX) to Santiago, you can fly into Cibao Intl. (STI) and Arturo Merino Benitez (SCL). Some flights may connect through major hubs like Charlotte-Douglas Intl. (CLT), Dallas-Fort Worth Intl. (DFW), Los Angeles Intl. (LAX) before reaching Santiago. Compare routes and airports on Expedia to find the best flight options for your travel plans.

Is it cheaper to buy a plane ticket from Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez) at the last minute?

Typically, booking a last minute flight from Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.

Is it cheaper to book a Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez) flight and hotel package?

Securing a Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez) Santiago Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.

Can I cancel or change the date of my flight from Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez)?

If you booked your Phoenix, AZ (PHX-Sky Harbor Intl.) to Santiago (SCL-Arturo Merino Benitez) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.