$553 Cheap Flights from Panama City (PTY) to Johannesburg (JNB)

View $553 flight on Wed, Sep 24, 2025Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to O.R. Tambo Intl. Airport (JNB)

Cheap Flights from Panama City to Johannesburg (PTY-JNB)

Prices were available within the past 7 days and start at $553 for one-way flights and $1,008 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Mon, Sep 1 - Mon, Sep 8
PTY
Panama City
JNB
Johannesburg
$1,008 Roundtrip, found 1 day ago
$1,008
Roundtrip
found 1 day ago
Select United flight, departing Mon, Sep 1 from Panama City to Johannesburg, returning Mon, Sep 8, priced at $1,008 found 1 day ago
United
Mon, Sep 1 - Mon, Sep 8
PTY
Panama City
JNB
Johannesburg
$1,013 Roundtrip, found 1 day ago
$1,013
Roundtrip
found 1 day ago
Select United flight, departing Mon, Sep 1 from Panama City to Johannesburg, returning Mon, Sep 8, priced at $1,013 found 1 day ago
United
Mon, Sep 1 - Mon, Sep 8
PTY
Panama City
JNB
Johannesburg
$1,053 Roundtrip, found 1 day ago
$1,053
Roundtrip
found 1 day ago
Select United flight, departing Mon, Sep 1 from Panama City to Johannesburg, returning Mon, Sep 8, priced at $1,053 found 1 day ago
United
Thu, Sep 25 - Fri, Oct 10
PTY
Panama City
JNB
Johannesburg
$1,054 Roundtrip, found 4 days ago
$1,054
Roundtrip
found 4 days ago
Select United flight, departing Thu, Sep 25 from Panama City to Johannesburg, returning Fri, Oct 10, priced at $1,054 found 4 days ago
United
Wed, Sep 3 - Mon, Sep 8
PTY
Panama City
JNB
Johannesburg
$1,059 Roundtrip, found 1 day ago
$1,059
Roundtrip
found 1 day ago
Select United flight, departing Wed, Sep 3 from Panama City to Johannesburg, returning Mon, Sep 8, priced at $1,059 found 1 day ago
United
Tue, Oct 28 - Tue, Nov 11
PTY
Panama City
JNB
Johannesburg
$1,064 Roundtrip, found 17 hours ago
$1,064
Roundtrip
found 17 hours ago
Select United flight, departing Tue, Oct 28 from Panama City to Johannesburg, returning Tue, Nov 11, priced at $1,064 found 17 hours ago
Copa
Mon, Nov 10 - Wed, Nov 19
PTY
Panama City
JNB
Johannesburg
$1,131 Roundtrip, found 2 days ago
$1,131
Roundtrip
found 2 days ago
Select Copa flight, departing Mon, Nov 10 from Panama City to Johannesburg, returning Wed, Nov 19, priced at $1,131 found 2 days ago
Turkish Airlines
Sat, Nov 1 - Fri, Nov 7
PTY
Panama City
JNB
Johannesburg
$1,489 Roundtrip, found 17 hours ago
$1,489
Roundtrip
found 17 hours ago
Select Turkish Airlines flight, departing Sat, Nov 1 from Panama City to Johannesburg, returning Fri, Nov 7, priced at $1,489 found 17 hours ago
Qatar Airways
Sat, Feb 7 - Mon, Feb 16
PTY
Panama City
JNB
Johannesburg
$1,977 Roundtrip, found 2 days ago
$1,977
Roundtrip
found 2 days ago
Select Qatar Airways flight, departing Sat, Feb 7 from Panama City to Johannesburg, returning Mon, Feb 16, priced at $1,977 found 2 days ago
Iberia
Mon, Oct 13 - Tue, Oct 21
PTY
Panama City
JNB
Johannesburg
$2,121 Roundtrip, found 5 days ago
$2,121
Roundtrip
found 5 days ago
Select Iberia flight, departing Mon, Oct 13 from Panama City to Johannesburg, returning Tue, Oct 21, priced at $2,121 found 5 days ago
Flights from Panama City (PTY) to Johannesburg (JNB)
Origin airport
Tocumen Intl.
Destination airport
O.R. Tambo Intl.
Airlines serving
Air France, British Airways, Delta, Emirates, Iberia, KLM, Qatar Airways, Turkish Airlines, United
Roundtrip price
$1,007
Distance
7581 mi

Panama City to Johannesburg Flights

The cheapest times to fly from Panama City to Johannesburg

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Johannesburg are during the month of September. You can find some of the cheapest flights from Panama City to Johannesburg with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Johannesburg

Sunday is one of the best days to book for cheap flights from Panama City to Johannesburg: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Johannesburg

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Johannesburg in 2025. You can also book with separate airlines for your outbound and return journeys, from $553 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Johannesburg flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Johannesburg airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to O.R. Tambo Intl. Airport (JNB) cost?
Grab a cheap one-way flight from $553 or cheap return flight from $1,008 from Tocumen Intl. Airport (PTY) to O.R. Tambo Intl. Airport (JNB) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Tocumen Intl. Airport (PTY) to O.R. Tambo Intl. Airport (JNB)?
The cheapest month to fly from PTY to JNB is September, when there's less demand. Off-peak season is generally when you'll find lower airfares between these airports.
What is the cheapest airline that flies from Tocumen Intl. Airport (PTY) to O.R. Tambo Intl. Airport (JNB)?
Use the filters on Expedia to compare airlines and find the cheapest carrier that'll fly you from PTY to JNB. Then, sort your results by "Price (lowest to highest)" to pick up the best deal available.
How many flights per day from Tocumen Intl. Airport (PTY) to O.R. Tambo Intl. Airport (JNB)?
You'll have to take a flight with a layover if you're traveling from Tocumen Intl. Airport (PTY) to O.R. Tambo Intl. Airport (JNB). There are no daily direct flights on this route. However, just filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from PTY to JNB?
Generally you'll find the most flight options available on a Friday. Tuesdays tend to be the quietest.* But this can change depending on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tocumen Intl. Airport (PTY) to O.R. Tambo Intl. Airport (JNB)?
To avoid potential delays on the Tocumen Intl. Airport (PTY) to O.R. Tambo Intl. Airport (JNB) route, travel before 3 PM. Flights after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to O.R. Tambo Intl. Airport (JNB) last-minute?
Last-minute fares from PTY to JNB are typically more expensive. For the best rates, start looking for flights ahead of time. That said, if you can play around with your travel dates, you may find a cheap fare right before your journey.
Is it cheaper to book a PTY to JNB flight and hotel package?
You'll typically save money by securing a PTY to JNB flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one convenient place. Once you've chosen your ideal flights and accommodations, consider other add-ons like car rentals, tours and activities.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to O.R. Tambo Intl. Airport (JNB)?
In most instances, you can modify or cancel your PTY to JNB flight. However, additional fees may apply, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline's guidelines and fees on flight changes, or if you want further information, go to our Customer Service portal.

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*Available to One Key members.