$1,126 Cheap Flights from Panama City (PTY) to Pisa (PSA)

View $1,126 flight on Mon, May 18, 2026Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Galileo Galilei Airport (PSA)

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Cheap Flights from Panama City to Pisa (PTY-PSA)

Prices were available within the past 7 days and start at $1,126 for one-way flights and $1,599 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Mon, May 18 - Mon, May 25
PTY
Panama City
PSA
Pisa
$1,599 Roundtrip, found 18 hours ago
$1,599
Roundtrip
found 18 hours ago
Select United flight, departing Mon, May 18 from Panama City to Pisa, returning Mon, May 25, priced at $1,599 found 18 hours ago
United
Mon, May 18 - Mon, May 25
PTY
Panama City
PSA
Pisa
$1,629 Roundtrip, found 18 hours ago
$1,629
Roundtrip
found 18 hours ago
Select United flight, departing Mon, May 18 from Panama City to Pisa, returning Mon, May 25, priced at $1,629 found 18 hours ago
Copa
Mon, May 18 - Mon, May 25
PTY
Panama City
PSA
Pisa
$1,656 Roundtrip, found 18 hours ago
$1,656
Roundtrip
found 18 hours ago
Select Copa flight, departing Mon, May 18 from Panama City to Pisa, returning Mon, May 25, priced at $1,656 found 18 hours ago
Copa
Mon, May 18 - Mon, May 25
PTY
Panama City
PSA
Pisa
$1,690 Roundtrip, found 18 hours ago
$1,690
Roundtrip
found 18 hours ago
Select Copa flight, departing Mon, May 18 from Panama City to Pisa, returning Mon, May 25, priced at $1,690 found 18 hours ago
Copa
Mon, May 18 - Mon, May 25
PTY
Panama City
PSA
Pisa
$1,697 Roundtrip, found 18 hours ago
$1,697
Roundtrip
found 18 hours ago
Select Copa flight, departing Mon, May 18 from Panama City to Pisa, returning Mon, May 25, priced at $1,697 found 18 hours ago
United
Mon, May 18 - Mon, May 25
PTY
Panama City
PSA
Pisa
$1,713 Roundtrip, found 18 hours ago
$1,713
Roundtrip
found 18 hours ago
Select United flight, departing Mon, May 18 from Panama City to Pisa, returning Mon, May 25, priced at $1,713 found 18 hours ago
Copa
Mon, May 18 - Mon, May 25
PTY
Panama City
PSA
Pisa
$1,724 Roundtrip, found 18 hours ago
$1,724
Roundtrip
found 18 hours ago
Select Copa flight, departing Mon, May 18 from Panama City to Pisa, returning Mon, May 25, priced at $1,724 found 18 hours ago
United
Mon, May 18 - Mon, May 25
PTY
Panama City
PSA
Pisa
$1,740 Roundtrip, found 18 hours ago
$1,740
Roundtrip
found 18 hours ago
Select United flight, departing Mon, May 18 from Panama City to Pisa, returning Mon, May 25, priced at $1,740 found 18 hours ago
Copa
Mon, May 18 - Mon, May 25
PTY
Panama City
PSA
Pisa
$1,747 Roundtrip, found 18 hours ago
$1,747
Roundtrip
found 18 hours ago
Select Copa flight, departing Mon, May 18 from Panama City to Pisa, returning Mon, May 25, priced at $1,747 found 18 hours ago
Copa
Mon, May 18 - Mon, May 25
PTY
Panama City
PSA
Pisa
$1,788 Roundtrip, found 18 hours ago
$1,788
Roundtrip
found 18 hours ago
Select Copa flight, departing Mon, May 18 from Panama City to Pisa, returning Mon, May 25, priced at $1,788 found 18 hours ago

Frequently asked questions

How much does a flight from Panama City (PTY-Tocumen Intl.) to Pisa (PSA-Galileo Galilei) cost?
You can find cheap one-way flights and cheap return flights from $1,599 PTY to PSA with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when PTY to PSA ticket fares go up or down.
What is the cheapest month to fly from Panama City (PTY-Tocumen Intl.) to Pisa (PSA-Galileo Galilei)?
The cheapest month to fly from PTY to PSA is May when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Panama City (PTY-Tocumen Intl.) to Pisa (PSA-Galileo Galilei)?
Enter PTY to PSA and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Panama City (PTY-Tocumen Intl.) to Pisa (PSA-Galileo Galilei)?
Copa, United and American Airlines are just some of the carriers that fly from Panama City (PTY) to Pisa (PSA). Use Expedia's flight search tool to compare airlines on this route and find our cheapest option for your trip. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Panama City (PTY-Tocumen Intl.) to Pisa (PSA-Galileo Galilei)?
To find a cheap flight from Panama City (PTY-Tocumen Intl.) to Pisa (PSA-Galileo Galilei), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Panama City (PTY-Tocumen Intl.) to Pisa (PSA-Galileo Galilei)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Panama City (PTY-Tocumen Intl.) to Pisa (PSA-Galileo Galilei)?
The earliest flight from Panama City (PTY) to Pisa (PSA) typically departs at around 7:10 AM, with service from Copa Airlines, Lufthansa, and Air Dolomiti. Starting your journey early can give you a full day to enjoy the sights of Pisa. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
How long does it take to fly from Panama City (PTY-Tocumen Intl.) to Pisa (PSA-Galileo Galilei)?
Flying from PTY to PSA with a connection usually takes about 15 hours 50 minutes, traveling roughly 5,776 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Panama City (PTY-Tocumen Intl.) to Pisa (PSA-Galileo Galilei)?
Business class seats are offered on the PTY to PSA route with Copa and American Airlines.
How do I earn miles on a Panama City (PTY-Tocumen Intl.) to Pisa (PSA-Galileo Galilei) flight with Expedia?
It's easy to earn miles on a Panama City (PTY-Tocumen Intl.) to Pisa (PSA-Galileo Galilei) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Pisa from Tocumen Intl. (PTY)?
If you're planning to travel to Pisa from Tocumen Intl. (PTY), you can fly into Galileo Galilei (PSA) Some flights may connect through major hubs like Juan Santamaria Intl. (SJO), Washington Dulles Intl. (IAD), El Dorado Intl. (BOG) before reaching Pisa. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Panama City (PTY-Tocumen Intl.) to Pisa (PSA-Galileo Galilei) at the last minute?
Typically, booking a last minute flight from Panama City (PTY-Tocumen Intl.) to Pisa (PSA-Galileo Galilei) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Panama City (PTY-Tocumen Intl.) to Pisa (PSA-Galileo Galilei) flight and hotel package?
Securing a Panama City (PTY-Tocumen Intl.) to Pisa (PSA-Galileo Galilei) Pisa Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Panama City (PTY-Tocumen Intl.) to Pisa (PSA-Galileo Galilei)?
If you booked your Panama City (PTY-Tocumen Intl.) to Pisa (PSA-Galileo Galilei) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Tocumen Intl.
Destination airport
Galileo Galilei
Airlines serving
United
Roundtrip price
$1,599
Distance
5775 mi

Book with confidence

Panama City to Pisa Flights

The cheapest times to fly from Panama City to Pisa

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Pisa are during the month of May. You can find some of the cheapest flights from Panama City to Pisa with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Pisa

Sunday is one of the best days to book for cheap flights from Panama City to Pisa: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Pisa

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Pisa in 2026. You can also book with separate airlines for your outbound and return journeys, from $1,126 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Pisa flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Pisa airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Panama City to Pisa Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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