$109 Cheap Flights from San Antonio (SAT) to Medellín (MDE)

View $109 flight on Thu, Jan 1, 2026Opens in a new window

Popular airlines from San Antonio International Airport (SAT) to Jose Maria Cordova Intl. Airport (MDE)

Cheap Flights from San Antonio to Medellín (SAT-MDE)

Prices were available within the past 7 days and start at $109 for one-way flights and $340 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Sat, Jan 3 - Sat, Jan 31
SAT
San Antonio
MDE
Medellin
$340 Roundtrip, found 2 days ago
$340
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Sat, Jan 3 from San Antonio to Medellin, returning Sat, Jan 31, priced at $340 found 2 days ago
Spirit Airlines
Sun, Dec 7 - Fri, Dec 12
SAT
San Antonio
MDE
Medellin
$345 Roundtrip, found 4 days ago
$345
Roundtrip
found 4 days ago
Select Spirit Airlines flight, departing Sun, Dec 7 from San Antonio to Medellin, returning Fri, Dec 12, priced at $345 found 4 days ago
Spirit Airlines
Sat, Jan 3 - Sat, Jan 31
SAT
San Antonio
MDE
Medellin
$355 Roundtrip, found 2 days ago
$355
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Sat, Jan 3 from San Antonio to Medellin, returning Sat, Jan 31, priced at $355 found 2 days ago
Spirit Airlines
Wed, Mar 18 - Tue, Mar 24
SAT
San Antonio
MDE
Medellin
$365 Roundtrip, found 22 hours ago
$365
Roundtrip
found 22 hours ago
Select Spirit Airlines flight, departing Wed, Mar 18 from San Antonio to Medellin, returning Tue, Mar 24, priced at $365 found 22 hours ago
Spirit Airlines
Wed, Feb 18 - Tue, Feb 24
SAT
San Antonio
MDE
Medellin
$368 Roundtrip, found 3 days ago
$368
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Wed, Feb 18 from San Antonio to Medellin, returning Tue, Feb 24, priced at $368 found 3 days ago
Spirit Airlines
Sun, Dec 7 - Thu, Dec 11
SAT
San Antonio
MDE
Medellin
$372 Roundtrip, found 1 day ago
$372
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Sun, Dec 7 from San Antonio to Medellin, returning Thu, Dec 11, priced at $372 found 1 day ago
American Airlines
Mon, Dec 8 - Fri, Dec 12
SAT
San Antonio
MDE
Medellin
$451 Roundtrip, found 12 hours ago
$451
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Mon, Dec 8 from San Antonio to Medellin, returning Fri, Dec 12, priced at $451 found 12 hours ago
United
Fri, Feb 6 - Mon, Feb 9
SAT
San Antonio
MDE
Medellin
$513 Roundtrip, just found
$513
Roundtrip
just found
Select United flight, departing Fri, Feb 6 from San Antonio to Medellin, returning Mon, Feb 9, priced at $513 just found
Delta
Mon, Apr 6 - Wed, Apr 22
SAT
San Antonio
MDE
Medellin
$526 Roundtrip, found 5 days ago
$526
Roundtrip
found 5 days ago
Select Delta flight, departing Mon, Apr 6 from San Antonio to Medellin, returning Wed, Apr 22, priced at $526 found 5 days ago
LATAM Airlines Group
Mon, Apr 13 - Tue, Apr 21
SAT
San Antonio
MDE
Medellin
$610 Roundtrip, found 4 days ago
$610
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Mon, Apr 13 from San Antonio to Medellin, returning Tue, Apr 21, priced at $610 found 4 days ago

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Find the cheapest month to fly from San Antonio (SAT) to Medellín (MDE)

October is typically the cheapest month to fly

From $305 - $771 per traveler.

Alternative airports near Medellín

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Jose Maria Cordova Intl. MDE. Cheapest option available. Average driving time to city center is 29 minutes. Flights from $470
MDE
Jose Maria Cordova Intl.
Cheapest
Average driving time to city center29 min
Flights from $470
Flights from San Antonio (SAT) to Medellín (MDE)
Origin airport
San Antonio Intl.
Destination airport
José María Córdova Intl.
Airlines serving
Aeromexico, American Airlines, Delta, LATAM Airlines Group, Spirit Airlines, United
Roundtrip price
$339
Distance
2203 mi

San Antonio to Medellín Flights

The cheapest times to fly from San Antonio to Medellín

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from San Antonio to Medellín are during the month of January. You can find some of the cheapest flights from San Antonio to Medellín with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from San Antonio to Medellín

Sunday is one of the best days to book for cheap flights from San Antonio to Medellín: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from San Antonio to Medellín

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from San Antonio to Medellín in 2025. You can also book with separate airlines for your outbound and return journeys, from $109 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap San Antonio to Medellín flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your San Antonio to Medellín airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from San Antonio Intl. Airport (SAT) to Jose Maria Cordova Intl. Airport (MDE) cost?
Secure a cheap one-way flight from $109 or cheap return flight from $340 from San Antonio Intl. Airport (SAT) to Jose Maria Cordova Intl. Airport (MDE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from San Antonio Intl. Airport (SAT) to Jose Maria Cordova Intl. Airport (MDE)?
The cheapest month to fly from SAT to MDE is January, when there's less demand. Off-peak season is usually when better flight deals are available between these airports.
What is the cheapest airline that flies from San Antonio Intl. Airport (SAT) to Jose Maria Cordova Intl. Airport (MDE)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest SAT to MDE flight.
How many flights per day from San Antonio Intl. Airport (SAT) to Jose Maria Cordova Intl. Airport (MDE)?
You'll need to hop on a flight with a layover if you're traveling from San Antonio Intl. Airport (SAT) to Jose Maria Cordova Intl. Airport (MDE). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from SAT to MDE?
You'll generally find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from San Antonio Intl. Airport (SAT) to Jose Maria Cordova Intl. Airport (MDE)?
To avoid potential delays on the San Antonio Intl. Airport (SAT) to Jose Maria Cordova Intl. Airport (MDE) route, aim to travel before 3 PM. Later departures have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from San Antonio Intl. Airport (SAT) to Jose Maria Cordova Intl. Airport (MDE) last-minute?
Booking your plane ticket from SAT to MDE right before your trip is usually more expensive. But if there's some wiggle room with your departure dates and times, you could score a cheap last-minute fare.
Is it cheaper to book a SAT to MDE flight and hotel package?
Opting for a SAT to MDE flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Choose from our impressive range of stays and then add car rentals, activities and flights to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from San Antonio Intl. Airport (SAT) to Jose Maria Cordova Intl. Airport (MDE)?
It's usually possible to cancel or reschedule your SAT to MDE flight. However, if it's been more than 24 hours since booking, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.