$327 Cheap Flights from Santo Domingo (SDQ) to Greenville (GSP)

View $327 flight on Wed, Oct 22, 2025Opens in a new window

Popular airlines from Las Americas Intl. Airport (SDQ) to Greenville-Spartanburg Intl. Airport (GSP)

Cheap Flights from Santo Domingo to Greenville (SDQ-GSP)

Prices were available within the past 7 days and start at $327 for one-way flights and $515 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Oct 28 - Sun, Nov 2
SDQ
Santo Domingo
GSP
Greenville
$515 Roundtrip, found 5 days ago
$515
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Oct 28 from Santo Domingo to Greenville, returning Sun, Nov 2, priced at $515 found 5 days ago
United
Wed, Oct 29 - Tue, Nov 11
SDQ
Santo Domingo
GSP
Greenville
$515 Roundtrip, found 4 days ago
$515
Roundtrip
found 4 days ago
Select United flight, departing Wed, Oct 29 from Santo Domingo to Greenville, returning Tue, Nov 11, priced at $515 found 4 days ago
Delta
Tue, Apr 28 - Tue, May 12
SDQ
Santo Domingo
GSP
Greenville
$516 Roundtrip, found 2 days ago
$516
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Apr 28 from Santo Domingo to Greenville, returning Tue, May 12, priced at $516 found 2 days ago
Delta
Tue, Oct 28 - Mon, Nov 3
SDQ
Santo Domingo
GSP
Greenville
$519 Roundtrip, found 5 days ago
$519
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Oct 28 from Santo Domingo to Greenville, returning Mon, Nov 3, priced at $519 found 5 days ago
American Airlines
Thu, Nov 6 - Sat, Nov 15
SDQ
Santo Domingo
GSP
Greenville
$521 Roundtrip, found 3 hours ago
$521
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Thu, Nov 6 from Santo Domingo to Greenville, returning Sat, Nov 15, priced at $521 found 3 hours ago
American Airlines
Fri, Dec 19 - Tue, Jan 13
SDQ
Santo Domingo
GSP
Greenville
$524 Roundtrip, found 7 hours ago
$524
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Fri, Dec 19 from Santo Domingo to Greenville, returning Tue, Jan 13, priced at $524 found 7 hours ago
American Airlines
Thu, Nov 6 - Sat, Nov 15
SDQ
Santo Domingo
GSP
Greenville
$526 Roundtrip, found 3 hours ago
$526
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Thu, Nov 6 from Santo Domingo to Greenville, returning Sat, Nov 15, priced at $526 found 3 hours ago
Delta
Wed, Oct 29 - Fri, Nov 14
SDQ
Santo Domingo
GSP
Greenville
$527 Roundtrip, found 5 days ago
$527
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, Oct 29 from Santo Domingo to Greenville, returning Fri, Nov 14, priced at $527 found 5 days ago
American Airlines
Thu, Nov 6 - Sat, Nov 15
SDQ
Santo Domingo
GSP
Greenville
$528 Roundtrip, found 3 hours ago
$528
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Thu, Nov 6 from Santo Domingo to Greenville, returning Sat, Nov 15, priced at $528 found 3 hours ago
Copa
Sun, Mar 15 - Thu, Apr 30
SDQ
Santo Domingo
GSP
Greenville
$896 Roundtrip, found 3 hours ago
$896
Roundtrip
found 3 hours ago
Select Copa flight, departing Sun, Mar 15 from Santo Domingo to Greenville, returning Thu, Apr 30, priced at $896 found 3 hours ago

Find the cheapest month to fly from Santo Domingo (SDQ) to Greenville (GSP)

February is typically the cheapest month to fly

From $507 - $584 per traveler.

Alternative airports near Greenville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Greenville-Spartanburg Intl. GSP. Cheapest option available. Average driving time to city center is 18 minutes. Flights from $568
GSP
Greenville-Spartanburg Intl.
Cheapest
Average driving time to city center18 min
Flights from $568

Frequently asked questions

How much does a flight from Las Americas Intl. Airport (SDQ) to Greenville-Spartanburg Intl. Airport (GSP) cost?
Lock in a cheap one-way flight from $327 or cheap return flight from $515 from Las Americas Intl. Airport (SDQ) to Greenville-Spartanburg Intl. Airport (GSP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Las Americas Intl. Airport (SDQ) to Greenville-Spartanburg Intl. Airport (GSP)?
October is the most affordable month to fly from SDQ to GSP. Traveling during an off-peak travel window is often the key to finding better deals on flights.
What is the cheapest airline that flies from Las Americas Intl. Airport (SDQ) to Greenville-Spartanburg Intl. Airport (GSP)?
Use the filters on Expedia to compare airlines and find the cheapest carrier that'll take you from SDQ to GSP. Then, sort your results by "Price (lowest to highest)" to pick up a great deal.
How many flights per day from Las Americas Intl. Airport (SDQ) to Greenville-Spartanburg Intl. Airport (GSP)?
Direct flights from Las Americas Intl. Airport (SDQ) to Greenville-Spartanburg Intl. Airport (GSP) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from SDQ to GSP?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Las Americas Intl. Airport (SDQ) to Greenville-Spartanburg Intl. Airport (GSP)?
To reach Greenville-Spartanburg Intl. Airport (GSP) without delays, book a flight that leaves from Las Americas Intl. Airport (SDQ) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Las Americas Intl. Airport (SDQ) to Greenville-Spartanburg Intl. Airport (GSP) last-minute?
Last-minute bookings from SDQ to GSP are typically more expensive. To secure the lowest rates, start looking for flights as soon as possible. That being said, if you can play around with your travel dates, you may land a cheap ticket right before you leave.
Is it cheaper to book a SDQ to GSP flight and hotel package?
Booking a SDQ to GSP flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels in one place. Choose from our impressive range of stays and then add flights, activities and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Las Americas Intl. Airport (SDQ) to Greenville-Spartanburg Intl. Airport (GSP)?
Typically, you can cancel or reschedule your SDQ to GSP flight. However, there may be additional fees, especially if you made your booking more than 24 hours ago. Check your itinerary for the airline's policies and fees on flight changes, or if you need further details, go to our Customer Service portal.

Travel information

Travel information

Origin airport
Las Americas Intl.
Destination airport
Greenville-Spartanburg Intl.
Airlines serving
American Airlines, Copa, Delta, United
Roundtrip price
$514
Distance
1372 mi

Book with confidence

Book with confidence

Santo Domingo to Greenville Flights

The cheapest times to fly from Santo Domingo to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santo Domingo to Greenville are during the month of October. You can find some of the cheapest flights from Santo Domingo to Greenville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santo Domingo to Greenville

Sunday is one of the best days to book for cheap flights from Santo Domingo to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santo Domingo to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santo Domingo to Greenville in 2025. You can also book with separate airlines for your outbound and return journeys, from $327 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santo Domingo to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santo Domingo to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Santo Domingo to Greenville Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.