Cheap Flights from St. Louis (STL) to São Tomé Island (TMS)

Popular airlines from St. Louis Lambert Intl. Airport (STL) to São Tomé Island (TMS-São Tomé Intl.)

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Frequently asked questions

How much does a flight from Lambert-St. Louis Intl. Airport (STL) to Sao Tome Intl. Airport (TMS) cost?
Grab a cheap one-way flight or cheap return flight from Lambert-St. Louis Intl. Airport (STL) to Sao Tome Intl. Airport (TMS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Lambert-St. Louis Intl. Airport (STL) to Sao Tome Intl. Airport (TMS)?
The cheapest month to fly from STL to TMS is , when there's less demand. Off-peak season is usually when airlines offer better prices between these airports.
What is the cheapest airline that flies from Lambert-St. Louis Intl. Airport (STL) to Sao Tome Intl. Airport (TMS)?
To find the cheapest airline flying from STL to TMS, use Expedia's filter tool. Customize your search based on your travel style, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Lambert-St. Louis Intl. Airport (STL) to Sao Tome Intl. Airport (TMS)?
Nonstop flights from Lambert-St. Louis Intl. Airport (STL) to Sao Tome Intl. Airport (TMS) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your travel dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from STL to TMS?
Usually you'll find the most flight options available on a Friday. Tuesdays tend to be the quietest.* However, this can vary depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Lambert-St. Louis Intl. Airport (STL) to Sao Tome Intl. Airport (TMS)?
To touch down at Sao Tome Intl. Airport (TMS) on schedule, book a flight that leaves from Lambert-St. Louis Intl. Airport (STL) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Lambert-St. Louis Intl. Airport (STL) to Sao Tome Intl. Airport (TMS) last-minute?
Waiting until just before your trip to book a ticket from STL to TMS often results in higher prices. While it's possible to find some last-minute discounts, they're not always guaranteed. Be flexible with your itinerary to boost your chances of getting a bargain.
Is it cheaper to book a STL to TMS flight and hotel package?
Compared with arranging flights and hotels separately, booking a STL to TMS flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one place will take the hassle out of planning your trip. Simply secure your flights and select from our wide range of stays, then customize your trip with extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Lambert-St. Louis Intl. Airport (STL) to Sao Tome Intl. Airport (TMS)?
You can usually reschedule or cancel your STL to TMS flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Origin airport
Lambert-St. Louis Intl.
Destination airport
São Tomé Intl.
Distance
6582 mi

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St. Louis to São Tomé Island Flights

The cheapest times to fly from St. Louis to São Tomé Island

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to São Tomé Island are during the month of . You can find some of the cheapest flights from St. Louis to São Tomé Island with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to São Tomé Island

Sunday is one of the best days to book for cheap flights from St. Louis to São Tomé Island: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to São Tomé Island

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to São Tomé Island in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to São Tomé Island flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to São Tomé Island airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

St. Louis to São Tomé Island Flights
*Available to One Key members.