$399 Cheap American Airlines flights Panama City (PTY) to Oranjestad (AUA)

Landing cheap one-way American Airlines flights from PTY to AUA from $399 on Expedia couldn't be easier — just filter by "Price (lowest to highest)." Alternatively, check out our budget-friendly round-trip fares from $1,316 for your next break.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Getting the best American Airlines deals from PTY to AUA is typically all about timing. You can save 17% on international flights when you book 18 to 29 days before takeoff instead of four to five months ahead. What's more, you can pocket 17% on average by buying your fare on a Sunday compared to a Friday, which is often the most expensive day to book.* It's a good idea to start checking out flights about one month before your departure date.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Browse American Airlines's earliest flights from PTY to AUA by selecting our "Early Morning" and "Morning" filters. Not only will you get to your destination sooner, early departures also experience 20% fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.