Flights to Lexington - Salisbury from Portland - $134

View $134 flight on Tue, Aug 12, 2025Opens in a new window

Popular airlines from Portland to Lexington - Salisbury

  • Alaska Airlines

    Alaska Airlines

  • American Airlines

    American Airlines

  • United

    United

  • Delta

    Delta

  • Southwest Airlines

    Southwest Airlines

  • Spirit Airlines

    Spirit Airlines

  • Frontier Airlines

    Frontier Airlines

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • one key icon

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Portland to Lexington - Salisbury (PDX-GSO)

Prices were available within the past 7 days and start at $134 for one-way flights and $278 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Thu, Aug 7 - Tue, Aug 12
PDX
Portland
CLT
Charlotte
$278 Roundtrip, just found
$278
Roundtrip
just found
Select Frontier Airlines flight, departing Thu, Aug 7 from Portland to Charlotte, returning Tue, Aug 12, priced at $278 just found
Spirit Airlines
Wed, Oct 1 - Sun, Oct 5
PDX
Portland
CLT
Charlotte
$283 Roundtrip, found 15 hours ago
$283
Roundtrip
found 15 hours ago
Select Spirit Airlines flight, departing Wed, Oct 1 from Portland to Charlotte, returning Sun, Oct 5, priced at $283 found 15 hours ago
Spirit Airlines
Wed, Sep 24 - Mon, Sep 29
PDX
Portland
CLT
Charlotte
$284 Roundtrip, found 14 hours ago
$284
Roundtrip
found 14 hours ago
Select Spirit Airlines flight, departing Wed, Sep 24 from Portland to Charlotte, returning Mon, Sep 29, priced at $284 found 14 hours ago
Southwest Airlines
Tue, Aug 19 - Sun, Aug 24
PDX
Portland
CLT
Charlotte
$303 Roundtrip, found 3 days ago
$303
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Tue, Aug 19 from Portland to Charlotte, returning Sun, Aug 24, priced at $303 found 3 days ago
American Airlines
Fri, Aug 29 - Tue, Sep 2
PDX
Portland
GSO
Greensboro
$309 Roundtrip, just found
$309
Roundtrip
just found
Select American Airlines flight, departing Fri, Aug 29 from Portland to Greensboro, returning Tue, Sep 2, priced at $309 just found
United
Thu, Aug 28 - Mon, Sep 1
PDX
Portland
GSO
Greensboro
$309 Roundtrip, found 13 hours ago
$309
Roundtrip
found 13 hours ago
Select United flight, departing Thu, Aug 28 from Portland to Greensboro, returning Mon, Sep 1, priced at $309 found 13 hours ago

Find the cheapest month to fly from Portland (PDX) to Charlotte (CLT)

September is typically the cheapest month to fly

From $138 - $347 per traveler.

Graph displaying average flight prices per month

Alternative airports

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Charlotte-Douglas Intl. CLT. Flights from $347
CLT
Charlotte-Douglas Intl.
Flights from $347
Select flight to Piedmont Triad Intl. GSO. Cheapest option available. Flights from $339
GSO
Piedmont Triad Intl.
Cheapest
Flights from $339
*Available to One Key members.