---
title: "$45 Cheap flights from Melipilla - Expedia.com"
description: "Cheap flights from Melipilla to all destinations. Find best deals for flights from Melipilla from top airlines with great prices at Expedia.com."
canonical: "https://www.expedia.com/lp/flights/3000006346/flights-from-melipilla"
language: en-US
market: US
currency: USD
prices_as_of: 2026-11-14T14:47:33Z
---

# $45 Cheap flights from Melipilla

[View $45 flight on Fri, Jan 1, 2027](https://www.expedia.com/Flights-Search?leg1=from:SCL,to:CJC,departure:1/1/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:44.05&airProductToken=AQosCioIyoIBEgI0MBjSWCCiEijTrKEDMNWtoQM4VUAAWAFqAlRTcgZVTFJEQ0wSCggBEAEYASoCSkEYASIECAEQASgCKAMoBDAB)

## Popular airlines from Melipilla

LATAM Airlines Group

Sky Airlines

Avianca

American Airlines

Delta

Air Canada

B & H Airlines

## Today's featured flight deals from Melipilla

Expedia compares millions of flights to find the best value deals for where you want to go.

Nonstop

Carry-on included

Lower price than typical

- [Select Turkish Airlines flight departing on Thu, Nov 26 at 11:45am from Santiago, returning on Thu, Dec 3 at 5:55am from São Paulo priced at $268](https://www.expedia.com/Flights-Search?leg1=from:SCL,to:GRU,departure:11/26/2026TANYT&leg2=from:GRU,to:SCL,departure:12/3/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&airOfferToken=v5-sos-3c02eb9c08c64f51bdd8aa6fd355c025-357-1~9.S.1~AQoCCAESBwjUBBABGAEoAlgCcAB6A2Jmc4gBhpGvZ6oBBwoDU0NMEACyAQcKA0dSVRAA~AQotCisI1JYBEgMyMTYY0lggpqQBKPWYngMw25qeAzhQQABYAWoCQ0xyBVBWQ0xSCi0KKwjUlgESAzIxNRimpAEg0lgo9-SeAzDs5p4DOFBAAFgBagJDTHIFUFZDTFISCggBEAEYASoCVEsYASIECAEQASgCKAMoBDAB&medianPrice=1420.00&displayPrice=267.20&src=dflp)
Santiago (SCL) · São Paulo (GRU) · Nonstop · 6-day trip · found 14 hours ago · 75% less than typical
- [Select Turkish Airlines flight departing on Wed, Nov 25 at 11:45am from Santiago, returning on Wed, Dec 2 at 5:55am from São Paulo priced at $268](https://www.expedia.com/Flights-Search?leg1=from:SCL,to:GRU,departure:11/25/2026TANYT&leg2=from:GRU,to:SCL,departure:12/2/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&airOfferToken=v5-sos-2fb0686a19934598b9afc4e4242c4bae-961-1~9.S.1~AQoCCAESBwjUBBABGAEoAlgCcAB6A2Jmc4gBt4qxZ6oBBwoDU0NMEACyAQcKA0dSVRAA~AQotCisI1JYBEgMyMTYY0lggpqQBKNWNngMwu4-eAzhQQABYAWoCQ0xyBVBWQ0xSCi0KKwjUlgESAzIxNRimpAEg0lgo19meAzDM254DOFBAAFgBagJDTHIFUFZDTFISCggBEAEYASoCVEsYASIECAEQASgCKAMoBDAB&medianPrice=1390.00&displayPrice=267.20&src=dflp)
Santiago (SCL) · São Paulo (GRU) · Nonstop · 6-day trip · found 5 hours ago · 75% less than typical
- [Select Turkish Airlines flight departing on Wed, Nov 25 at 11:45am from Santiago, returning on Mon, Nov 30 at 5:55am from São Paulo priced at $268](https://www.expedia.com/Flights-Search?leg1=from:SCL,to:GRU,departure:11/25/2026TANYT&leg2=from:GRU,to:SCL,departure:11/30/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&airOfferToken=v5-sos-6db8581154ae46578905f7159a19bc04-110-1~9.S.1~AQoCCAESBwjUBBABGAEoAlgCcAB6A2Jmc4gBt-avZ6oBBwoDU0NMEACyAQcKA0dSVRAA~AQotCisI1JYBEgMyMTYY0lggpqQBKNWNngMwu4-eAzhQQABYAWoCQ0xyBVBWQ0xSCi0KKwjUlgESAzIxNRimpAEg0lgol8OeAzCMxZ4DOFBAAFgBagJDTHIFUFZDTFISCggBEAEYASoCVEsYASIECAEQASgCKAMoBDAB&medianPrice=1334.00&displayPrice=267.20&src=dflp)
Santiago (SCL) · São Paulo (GRU) · Nonstop · 4-day trip · found 11 hours ago · 75% less than typical

## Cheapest flights from Melipilla

Prices were available within the past 7 days and start at $45 for one-way flights and $89 for roundtrip, for the period specified. Prices and availability are subject to change.

All deals

One way

Roundtrip

[Select B & H Airlines flight, departing Wed, Dec 30 from Santiago to Calama, returning Sun, Jan 3, priced at $89 Just found](https://www.expedia.com/Flights-Search?leg1=from:SCL,to:CJC,departure:12/30/2026TANYT&leg2=from:CJC,to:SCL,departure:1/3/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:88.10&airProductToken=AQosCioIyoIBEgI0NhjSWCCiEij8lKEDMP6VoQM4VUAAWAFqAlRTcgZVTFJEQ0wKLAoqCMqCARICNDkYohIg0lgomsmhAzCayqEDOFVAAFgBagJUU3IGVUxSRENMEgoIARABGAEqAkpBGAEiBAgBEAEoAigDKAQwAQ)

Wed, Dec 30 - Sun, Jan 3 · SCL · CJC · Roundtrip

[Select B & H Airlines flight, departing Fri, Dec 4 from Santiago to Calama, returning Mon, Dec 7, priced at $92 Found 2 hours ago](https://www.expedia.com/Flights-Search?leg1=from:SCL,to:CJC,departure:12/4/2026TANYT&leg2=from:CJC,to:SCL,departure:12/7/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:91.10&airProductToken=AQosCioIyoIBEgI0OBjSWCCiEiiv954DMLH4ngM4VUAAWAFqAlRTcgZVTFJEQ0wKLQorCMqCARIDNjgxGKISINJYKJCTnwMwkJSfAzhYQABYAWoCVFNyBlhMUkRDTBIKCAEQARgBKgJKQRgBIgQIARABKAIoAygEMAE)

Fri, Dec 4 - Mon, Dec 7 · SCL · CJC · Roundtrip

[Select B & H Airlines flight, departing Wed, Jan 6 from Santiago to Calama, returning Fri, Jan 8, priced at $95 Found 3 hours ago](https://www.expedia.com/Flights-Search?leg1=from:SCL,to:CJC,departure:1/6/2027TANYT&leg2=from:CJC,to:SCL,departure:1/8/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:94.10&airProductToken=AQosCioIyoIBEgI0MhjSWCCiEii846EDML7koQM4WEAAWAFqAlRTcgZYTFJEQ0wKLAoqCMqCARICNDUYohIg0lgosoGiAzCygqIDOFhAAFgBagJUU3IGWExSRENMEgoIARABGAEqAkpBGAEiBAgBEAEoAigDKAQwAQ)

Wed, Jan 6 - Fri, Jan 8 · SCL · CJC · Roundtrip

[Select Sky Airlines flight, departing Fri, Dec 4 from Santiago to Calama, returning Mon, Dec 7, priced at $97 Found 2 hours ago](https://www.expedia.com/Flights-Search?leg1=from:SCL,to:CJC,departure:12/4/2026TANYT&leg2=from:CJC,to:SCL,departure:12/7/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:96.40&airProductToken=AQouCiwIyGQSAzI2OBjSWCCiEijT9Z4DMNT2ngM4WEAAWAFqAlpPcghYWk8wMDAwMBIKCAEQARgBKgJIMhgBIgQIARABKAIoAygEMAE)

Fri, Dec 4 - Mon, Dec 7 · SCL · CJC · Roundtrip

[Select Sky Airlines flight, departing Fri, Dec 4 from Santiago to Calama, returning Mon, Dec 7, priced at $98 Found 2 hours ago](https://www.expedia.com/Flights-Search?leg1=from:SCL,to:CJC,departure:12/4/2026TANYT&leg2=from:CJC,to:SCL,departure:12/7/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:97.40&airProductToken=AQouCiwIyGQSAzI2OBjSWCCiEijT9Z4DMNT2ngM4WEAAWAFqAlpPcghYWk8wMDAwMAouCiwIyGQSAzI1ORiiEiDSWCi0mZ8DMLGanwM4WEAAWAFqAlpPcghYWk8wMDAwMBIKCAEQARgBKgJIMhgBIgQIARABKAIoAygEMAE)

Fri, Dec 4 - Mon, Dec 7 · SCL · CJC · Roundtrip

[Select Sky Airlines flight, departing Wed, May 26 from Santiago to Calama, returning Fri, May 28, priced at $98 Found 8 hours ago](https://www.expedia.com/Flights-Search?leg1=from:SCL,to:CJC,departure:5/26/2027TANYT&leg2=from:CJC,to:SCL,departure:5/28/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:97.60&airProductToken=AQovCi0IyGQSBDEyNDIY0lggohIo-IquAzD5i64DOFhAAFgBagJaT3IIWFpPMDAwMDAKLwotCMhkEgQxNzQxGKISINJYKN-irgMwqKSuAzhYQABYAWoCWk9yCFhaTzAwMDAwEgoIARABGAEqAkgyGAEiBAgBEAEoAigDKAQwAQ)

Wed, May 26 - Fri, May 28 · SCL · CJC · Roundtrip

[Select B & H Airlines flight, departing Wed, Dec 30 from Santiago to Calama, returning Sun, Jan 3, priced at $101 Just found](https://www.expedia.com/Flights-Search?leg1=from:SCL,to:CJC,departure:12/30/2026TANYT&leg2=from:CJC,to:SCL,departure:1/3/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:100.10&airProductToken=AQosCioIyoIBEgIzNhjSWCCiEijDk6EDMMWUoQM4VUAAWAFqAlRTcgZVTFJEQ0wKLAoqCMqCARICNDUYohIg0lgo-MihAzD4yaEDOFdAAFgBagJUU3IGV0xSRENMEgoIARABGAEqAkpBGAEiBAgBEAEoAigDKAQwAQ)

Wed, Dec 30 - Sun, Jan 3 · SCL · CJC · Roundtrip

[Select LATAM Airlines Group flight, departing Wed, Dec 30 from Santiago to Calama, returning Sun, Jan 3, priced at $110 Just found](https://www.expedia.com/Flights-Search?leg1=from:SCL,to:CJC,departure:12/30/2026TANYT&leg2=from:CJC,to:SCL,departure:1/3/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:109.62&airProductToken=AQovCi0IzIIBEgMxNDQY0lggohIolZShAzCVlaEDOEdAAFgBagJRUHIIRzBYUVA1WkoKLwotCMyCARIDMzg1GKISINJYKLHJoQMwrcqhAzhHQABYAWoCUVByCEcwWFFQNVpKEgoIAhABGAIqAkxBGAEiBAgBEAEoAigEKAYwAQ)

Wed, Dec 30 - Sun, Jan 3 · SCL · CJC · Roundtrip

[Select British Airways flight, departing Wed, Mar 31 from Santiago to Buenos Aires, returning Sat, Apr 3, priced at $254 Just found](https://www.expedia.com/Flights-Search?leg1=from:SCL,to:EZE,departure:3/31/2027TANYT&leg2=from:EZE,to:SCL,departure:4/3/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:253.40&airProductToken=AQoyCjAIwoIBEgMyNDQY0lggpCYo8papAzDql6kDOE9AAFgBagVOT0JBR3IIT05OQzYwQjcKMgowCMKCARIDMjQ1GKQmINJYKOe2qQMw7repAzhPQABYAWoFTk9CQUdyCE9OTkM2MEI3EgoIARABGAEqAkJBGAEiBAgBEAEoAigDMA0)

Wed, Mar 31 - Sat, Apr 3 · SCL · EZE · Roundtrip

[Select Aerolineas Argentinas flight, departing Wed, Mar 31 from Santiago to Buenos Aires, returning Sat, Apr 3, priced at $263 Just found](https://www.expedia.com/Flights-Search?leg1=from:SCL,to:AEP,departure:3/31/2027TANYT&leg2=from:AEP,to:SCL,departure:4/3/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:262.40&airProductToken=AQouCiwIwaQBEgQxMjg1GNJYIIB5KMOaqQMwwJupAzhWQABYAWoCRUJyBlZPV0lFQgouCiwIwaQBEgQxMjgwGIB5INJYKNi2qQMw6bepAzhWQABYAWoCRUJyBlZPV0lFQhIKCAEQARgBKgJBUhgBIgQIARABKAIoAygEMAE)

Wed, Mar 31 - Sat, Apr 3 · SCL · AEP · Roundtrip

## How to Find Cheap Flights from Melipilla

### How much is a flight from Melipilla?

This week, flights from Melipilla are available between $89 – $263\.

### How to find cheap flights from Melipilla?

Expedia makes it easy to compare cheap flights from Melipilla to many destinations. Check out excellent deals on domestic and international flights from Melipilla. Once you select an offer, use our filters and sort by “Price (Lowest)” to see some of the cheapest and suitable options.

### How can I get the best deal on flights from Melipilla?

On Expedia, you have some of best airline ticket deals at your fingertips. Whether it’s a beach escape with your partner, a family vacation with your kids, or business trip with colleagues, these low airline ticket prices mean more savings for you. An excellent strategy for finding some of the best deals on flights from Melipilla is to be flexible with your dates. Within each offer, you can compare prices for similar timeframes using our “Show flexible dates” feature. Depending on your destination, direct flights from Melipilla may be more expensive. Airlines with strict bag policies or fees can also impact your costs.

### What is the best airline to fly from Melipilla?

At Expedia, we give you all the available options from our reputable partners. Select the airline that best suits your preferences and membership loyalties. You can fly from Melipilla with: B & H Airlines, Sky Airlines, LATAM Airlines Group, Aerolineas Argentinas, British Airways.

### What is the best month to fly from Melipilla?

One of the cheapest times to fly from Melipilla airport(s) is December, based on the current list of flights available now. Prices on plane tickets vary considerably throughout the year due to availability and seasonal demand.

### Are there any last-minute flights from Melipilla?

Expedia is the place to find last-minute flights from Melipilla, making it easy for you to compare prices on flights in the near future for different combinations of travel dates and from multiple airlines. We source some of the best deals for you and display some of the best offers available over the next 2 weeks.

### Why book your ticket with Expedia?

Booking flights from Melipilla with Expedia is the obvious choice to get low prices, save money, and see more value from every dollar spent. We show you some of the best deals happening right now and provide a vast inventory of airlines and flight routes to choose from, so you can find some of the cheapest flights from Melipilla. You can customize your journey to your timeline, route preferences, budget, rewards programs, and more.

### Can I change/cancel my flight?

Some flights can be changed or canceled, but fees and refunds will depend on the unique terms of your flight agreement. Airlines have different rules and restrictions for exchanging or refunding flights. For more information, go to your itinerary or visit our [customer service portal](https://www.expedia.com/service/). We recommend choosing flights with no change fees for the most flexibility. Filter by “Flexible change policies” to see flights with no change fees.

## Travel information

| Origin city name         | Santiago                                                                                                                                                                                                                                                                                                                                                                                                                                                    |
| ------------------------ | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |
| Origin airport           | Santiago Intl. Airport                                                                                                                                                                                                                                                                                                                                                                                                                                      |
| Origin airport IATA code | SCL                                                                                                                                                                                                                                                                                                                                                                                                                                                         |
| Airlines serving         | LATAM Airlines Group, Sky Airlines, Avianca, American Airlines, Delta, Air Canada, B & H Airlines, Aerolineas Argentinas, KLM, Iberia, British Airways, Copa, Aeromexico, Air France, United, Turkish Airlines, Qantas Airways, GOL Linhas Aereas S.A., Air Europa, Cathay Pacific, Qatar Airways, Sterling Blue, Korean Air, Malaysia Airlines, WestJet, Finnair, All Nippon Airways, China Eastern Airlines, Boliviana De Aviacion, EL AL Israel Airlines |
| Popular airline          | LATAM Airlines Group                                                                                                                                                                                                                                                                                                                                                                                                                                        |
| Roundtrip price          | $89                                                                                                                                                                                                                                                                                                                                                                                                                                                         |

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- [Car rental Calera de Tango](https://www.expedia.com/Car-Rentals-In-Calera-De-Tango.d3000414522.Car-Rental-Guide)
- [Car rental Melipilla](https://www.expedia.com/Car-Rentals-In-Melipilla.d3000006346.Car-Rental-Guide)
- [Car rental Talagante](https://www.expedia.com/Car-Rentals-In-Talagante.d3000367097.Car-Rental-Guide)
- [Car rental Peñaflor](https://www.expedia.com/Car-Rentals-In-Penaflor.d3000374693.Car-Rental-Guide)
- [Car rental Curacaví](https://www.expedia.com/Car-Rentals-In-Curacavi.d3000401302.Car-Rental-Guide)
- [Alamo Rent A Car Rental Cars in Calera de Tango](https://www.expedia.com/Alamo-Rent-A-Car-Car-Rentals-In-Calera-De-Tango.d3000414522-c6.Car-Rental-Guide-Suppliers)
- [Pomaire Vacation Rentals](https://www.expedia.com/Pomaire-Vacation-Rentals.d3000431889.Travel-Guide-VacationRentals)
- [El Monte Vacation Rentals](https://www.expedia.com/El-Monte-Vacation-Rentals.d3000374694.Travel-Guide-VacationRentals)
- [Melipilla Vacation Rentals](https://www.expedia.com/Melipilla-Vacation-Rentals.d3000006346.Travel-Guide-VacationRentals)
- [Things to do in Melipilla](https://www.expedia.com/Things-To-Do-In-Melipilla.d3000006346.Travel-Guide-Activities)
- [Things to do in Talagante](https://www.expedia.com/Things-To-Do-In-Talagante.d3000367097.Travel-Guide-Activities)
- [Things to do in Isla de Maipo](https://www.expedia.com/Things-To-Do-In-Isla-De-Maipo.d6236027.Travel-Guide-Activities)
- [Things to do in Curacaví](https://www.expedia.com/Things-To-Do-In-Curacavi.d3000401302.Travel-Guide-Activities)
- [Things to do in Pomaire](https://www.expedia.com/Things-To-Do-In-Pomaire.d3000431889.Travel-Guide-Activities)

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