Cheap Flights from St. Louis (XLS) to São Tomé Island (TMS)

Popular airlines from St. Louis (XLS) to São Tomé Island (TMS-São Tomé Intl.)

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Frequently asked questions

How much does a flight from St. Louis (XLS) to Sao Tome Intl. Airport (TMS) cost?
Lock in a cheap one-way flight or cheap return flight from St. Louis (XLS) to Sao Tome Intl. Airport (TMS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from St. Louis (XLS) to Sao Tome Intl. Airport (TMS)?
Planning your trip for is a good way to save, as it's the cheapest month for flights between XLS and TMS. You'll typically find the lowest prices during the off-season.
What is the cheapest airline that flies from St. Louis (XLS) to Sao Tome Intl. Airport (TMS)?
To find the cheapest airline flying from XLS to TMS, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from St. Louis (XLS) to Sao Tome Intl. Airport (TMS)?
Nonstop flights from St. Louis (XLS) to Sao Tome Intl. Airport (TMS) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from XLS to TMS?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can vary depending on a number of factors, such as the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from St. Louis (XLS) to Sao Tome Intl. Airport (TMS)?
To avoid possible delays on the St. Louis (XLS) to Sao Tome Intl. Airport (TMS) route, aim to travel before 3 PM. Flights after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from St. Louis (XLS) to Sao Tome Intl. Airport (TMS) last-minute?
Holding off until just before your departure to book a flight from XLS to TMS often results in higher prices. While you may find some last-minute discounts, there's no guarantee. Allow some flexibility in your schedule for a better chance of getting a bargain.
Is it cheaper to book a XLS to TMS flight and hotel package?
Opting for a XLS to TMS flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Select from our extensive range of hotels and then add car rentals, flights and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from St. Louis (XLS) to Sao Tome Intl. Airport (TMS)?
Typically, it's possible to reschedule or cancel your XLS to TMS flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Travel information

Origin airport
St. Louis
Destination airport
São Tomé Intl.
Distance
1914 mi

Book with confidence

Book with confidence

St. Louis to São Tomé Island Flights

The cheapest times to fly from St. Louis to São Tomé Island

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to São Tomé Island are during the month of . You can find some of the cheapest flights from St. Louis to São Tomé Island with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to São Tomé Island

Sunday is one of the best days to book for cheap flights from St. Louis to São Tomé Island: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to São Tomé Island

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to São Tomé Island in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to São Tomé Island flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to São Tomé Island airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

St. Louis to São Tomé Island Flights
*Available to One Key members.