Flights to Winston-Salem from Des Moines - $136

View $136 flight on Tue, Oct 7, 2025Opens in a new window

Popular airlines from Des Moines to Winston-Salem

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Cheap Flights from Des Moines to Winston-Salem (DSM-GSO)

Prices were available within the past 7 days and start at $136 for one-way flights and $249 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Aug 27 - Mon, Sep 1
DSM
Des Moines
GSO
Greensboro
$249 Roundtrip, found 2 hours ago
$249
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Wed, Aug 27 from Des Moines to Greensboro, returning Mon, Sep 1, priced at $249 found 2 hours ago
Delta
Wed, Aug 27 - Mon, Sep 1
DSM
Des Moines
GSO
Greensboro
$249 Roundtrip, found 2 hours ago
$249
Roundtrip
found 2 hours ago
Select Delta flight, departing Wed, Aug 27 from Des Moines to Greensboro, returning Mon, Sep 1, priced at $249 found 2 hours ago
United
Wed, Aug 27 - Mon, Sep 1
DSM
Des Moines
GSO
Greensboro
$249 Roundtrip, found 2 hours ago
$249
Roundtrip
found 2 hours ago
Select United flight, departing Wed, Aug 27 from Des Moines to Greensboro, returning Mon, Sep 1, priced at $249 found 2 hours ago
Delta
Fri, Aug 15 - Sun, Aug 31
DSM
Des Moines
GSO
Greensboro
$254 Roundtrip, found 11 hours ago
$254
Roundtrip
found 11 hours ago
Select Delta flight, departing Fri, Aug 15 from Des Moines to Greensboro, returning Sun, Aug 31, priced at $254 found 11 hours ago
United
Wed, Aug 27 - Mon, Sep 1
DSM
Des Moines
GSO
Greensboro
$254 Roundtrip, found 2 hours ago
$254
Roundtrip
found 2 hours ago
Select United flight, departing Wed, Aug 27 from Des Moines to Greensboro, returning Mon, Sep 1, priced at $254 found 2 hours ago
United
Thu, Aug 21 - Sun, Aug 24
DSM
Des Moines
GSO
Greensboro
$255 Roundtrip, found 17 hours ago
$255
Roundtrip
found 17 hours ago
Select United flight, departing Thu, Aug 21 from Des Moines to Greensboro, returning Sun, Aug 24, priced at $255 found 17 hours ago

Find the cheapest month to fly from Des Moines (DSM) to Greensboro (GSO)

September is typically the cheapest month to fly

From $198 - $478 per traveler.

Graph displaying average flight prices per month

Alternative airports near Winston-Salem

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Piedmont Triad Intl. GSO. Cheapest option available. Average driving time to city center is 29 minutes. Flights from $254
GSO
Piedmont Triad Intl.
Cheapest
Average driving time to city center29 min
Flights from $254
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