Cheap Flights from Des Moines (DSM) to São Tomé Island (TMS)

Popular airlines from Des Moines International Airport (DSM) to São Tomé Island (TMS-São Tomé Intl.)

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Sao Tome Intl. Airport (TMS) cost?
Snag a cheap one-way flight or cheap return flight from Des Moines Intl. Airport (DSM) to Sao Tome Intl. Airport (TMS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Sao Tome Intl. Airport (TMS)?
The cheapest month to fly from DSM to TMS is , when demand is low. Off-peak season is typically when you'll find lower airfares between these airports.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Sao Tome Intl. Airport (TMS)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest DSM to TMS flight.
How many flights per day from Des Moines Intl. Airport (DSM) to Sao Tome Intl. Airport (TMS)?
Nonstop flights from Des Moines Intl. Airport (DSM) to Sao Tome Intl. Airport (TMS) aren't available daily, so you'll have to take a flight with a layover. Explore your options with our filter tool. Enter your travel details and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from DSM to TMS?
Usually you'll find the largest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* But this can change based on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Sao Tome Intl. Airport (TMS)?
To avoid potential delays on the Des Moines Intl. Airport (DSM) to Sao Tome Intl. Airport (TMS) route, aim to fly before 3 PM. Flights after this time have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Sao Tome Intl. Airport (TMS) last-minute?
Booking your flight from DSM to TMS shortly before your journey is usually more expensive. However, if you're flexible with your departure dates and times, you could snag a cheap last-minute fare.
Is it cheaper to book a DSM to TMS flight and hotel package?
Compared with arranging flights and hotels separately, booking a DSM to TMS flight and hotel package with Expedia could result in significant savings. What's more, having everything in one convenient place will take the stress out of planning your trip. Just secure your flights and select from our wide range of stays, then customize your trip with extras like car rentals and activities.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Sao Tome Intl. Airport (TMS)?
If you reserved your DSM to TMS flight in the last 24 hours, you may be able to modify or cancel it without fees. Depending on the airline and the fare type you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you'd like more information.

Travel information

Travel information

Origin airport
Des Moines Intl.
Destination airport
São Tomé Intl.
Distance
6735 mi

Book with confidence

Book with confidence

Des Moines to São Tomé Island Flights

The cheapest times to fly from Des Moines to São Tomé Island

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to São Tomé Island are during the month of . You can find some of the cheapest flights from Des Moines to São Tomé Island with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to São Tomé Island

Sunday is one of the best days to book for cheap flights from Des Moines to São Tomé Island: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to São Tomé Island

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to São Tomé Island in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to São Tomé Island flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to São Tomé Island airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Des Moines to São Tomé Island Flights
*Available to One Key members.