Cheap Flights from Louisville (SDF) to São Tomé Island (TMS)

Popular airlines from Louisville Intl. Airport (SDF) to São Tomé Island (TMS-São Tomé Intl.)

  • notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
  • deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash

Black Friday Sale

Limited-time deals: Save up to 50% on select hotels.
Flights from Louisville (SDF) to São Tomé Island (TMS)
Origin airport
Louisville Intl.
Destination airport
São Tomé Intl.
Distance
6335 mi

Louisville to São Tomé Island Flights

The cheapest times to fly from Louisville to São Tomé Island

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Louisville to São Tomé Island are during the month of . You can find some of the cheapest flights from Louisville to São Tomé Island with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Louisville to São Tomé Island

Sunday is one of the best days to book for cheap flights from Louisville to São Tomé Island: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Louisville to São Tomé Island

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Louisville to São Tomé Island in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Louisville to São Tomé Island flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Louisville to São Tomé Island airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Louisville Intl. Airport (SDF) to Sao Tome Intl. Airport (TMS) cost?
Grab a cheap one-way flight or cheap return flight from Louisville Intl. Airport (SDF) to Sao Tome Intl. Airport (TMS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Louisville Intl. Airport (SDF) to Sao Tome Intl. Airport (TMS)?
is the least expensive month to fly from SDF to TMS. Traveling outside of peak seasons is often the key to scoring lower fares.
What is the cheapest airline that flies from Louisville Intl. Airport (SDF) to Sao Tome Intl. Airport (TMS)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest SDF to TMS flight.
How many flights per day from Louisville Intl. Airport (SDF) to Sao Tome Intl. Airport (TMS)?
There are no daily direct flights from Louisville Intl. Airport (SDF) to Sao Tome Intl. Airport (TMS). But you can choose flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be cruising above the clouds in no time.
What day of the week has the most flights from SDF to TMS?
Usually you'll find the largest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* However, this can change depending on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Louisville Intl. Airport (SDF) to Sao Tome Intl. Airport (TMS)?
Choose a flight from Louisville Intl. Airport (SDF) to Sao Tome Intl. Airport (TMS) that leaves before 3 PM to reduce the likelihood of delays. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Louisville Intl. Airport (SDF) to Sao Tome Intl. Airport (TMS) last-minute?
Last-minute bookings from SDF to TMS are typically more expensive. To lock in the lowest rates, start looking for flights as early as possible. That said, if your travel plans are flexible, it's possible to find a cheap fare just before your departure.
Is it cheaper to book a SDF to TMS flight and hotel package?
Booking a SDF to TMS flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip all in one place. Pick from our wide range of accommodations and then add activities, flights and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Louisville Intl. Airport (SDF) to Sao Tome Intl. Airport (TMS)?
Usually, it's possible to cancel or reschedule your SDF to TMS flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more details on our Customer Service portal.
*Available to One Key members.