$221 Cheap Flights from Amarillo (AMA) to Tupelo (TUP)

View $221 flight on Tue, Apr 28, 2026Opens in a new window

Popular airlines from Amarillo, TX (AMA-Rick Husband Amarillo Intl.) to Tupelo, MS (TUP-Tupelo Regional)

Cheap Flights from Amarillo to Tupelo (AMA-TUP)

Prices were available within the past 7 days and start at $221 for one-way flights and $437 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Tue, Feb 10 - Tue, Feb 24
AMA
Amarillo
TUP
Tupelo
$437 Roundtrip, found 6 days ago
$437
Roundtrip
found 6 days ago
Select United flight, departing Tue, Feb 10 from Amarillo to Tupelo, returning Tue, Feb 24, priced at $437 found 6 days ago
United
Wed, Feb 18 - Mon, Mar 2
AMA
Amarillo
TUP
Tupelo
$446 Roundtrip, found 6 days ago
$446
Roundtrip
found 6 days ago
Select United flight, departing Wed, Feb 18 from Amarillo to Tupelo, returning Mon, Mar 2, priced at $446 found 6 days ago
United
Mon, Feb 9 - Tue, Feb 24
AMA
Amarillo
TUP
Tupelo
$447 Roundtrip, found 6 days ago
$447
Roundtrip
found 6 days ago
Select United flight, departing Mon, Feb 9 from Amarillo to Tupelo, returning Tue, Feb 24, priced at $447 found 6 days ago
United
Tue, Feb 24 - Thu, Mar 12
AMA
Amarillo
TUP
Tupelo
$456 Roundtrip, found 6 days ago
$456
Roundtrip
found 6 days ago
Select United flight, departing Tue, Feb 24 from Amarillo to Tupelo, returning Thu, Mar 12, priced at $456 found 6 days ago
United
Wed, Feb 25 - Wed, Mar 11
AMA
Amarillo
TUP
Tupelo
$458 Roundtrip, found 6 days ago
$458
Roundtrip
found 6 days ago
Select United flight, departing Wed, Feb 25 from Amarillo to Tupelo, returning Wed, Mar 11, priced at $458 found 6 days ago
United
Thu, Feb 12 - Wed, Feb 25
AMA
Amarillo
TUP
Tupelo
$459 Roundtrip, found 6 days ago
$459
Roundtrip
found 6 days ago
Select United flight, departing Thu, Feb 12 from Amarillo to Tupelo, returning Wed, Feb 25, priced at $459 found 6 days ago
United
Wed, Feb 18 - Wed, Mar 4
AMA
Amarillo
TUP
Tupelo
$467 Roundtrip, found 6 days ago
$467
Roundtrip
found 6 days ago
Select United flight, departing Wed, Feb 18 from Amarillo to Tupelo, returning Wed, Mar 4, priced at $467 found 6 days ago
United
Mon, Mar 23 - Tue, Apr 7
AMA
Amarillo
TUP
Tupelo
$468 Roundtrip, found 6 days ago
$468
Roundtrip
found 6 days ago
Select United flight, departing Mon, Mar 23 from Amarillo to Tupelo, returning Tue, Apr 7, priced at $468 found 6 days ago
United
Mon, Mar 23 - Wed, Apr 8
AMA
Amarillo
TUP
Tupelo
$469 Roundtrip, found 6 days ago
$469
Roundtrip
found 6 days ago
Select United flight, departing Mon, Mar 23 from Amarillo to Tupelo, returning Wed, Apr 8, priced at $469 found 6 days ago
United
Tue, Feb 24 - Tue, Mar 10
AMA
Amarillo
TUP
Tupelo
$476 Roundtrip, found 6 days ago
$476
Roundtrip
found 6 days ago
Select United flight, departing Tue, Feb 24 from Amarillo to Tupelo, returning Tue, Mar 10, priced at $476 found 6 days ago

Alternative airports near Tupelo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tupelo Regional TUP. Cheapest and Closest option available. Average driving time to city center is 8 minutes. Flights from $447
TUP
Tupelo Regional
CheapestClosest
Average driving time to city center8 min
Flights from $447
Flights from Amarillo (AMA) to Tupelo (TUP)
Origin airport
Rick Husband Amarillo Intl.
Destination airport
Tupelo Regional
Roundtrip price
$437
Distance
737 mi

Amarillo to Tupelo Flights

The cheapest times to fly from Amarillo to Tupelo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Amarillo to Tupelo are during the month of February. You can find some of the cheapest flights from Amarillo to Tupelo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Amarillo to Tupelo

Sunday is one of the best days to book for cheap flights from Amarillo to Tupelo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Amarillo to Tupelo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Amarillo to Tupelo in 2026. You can also book with separate airlines for your outbound and return journeys, from $221 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Amarillo to Tupelo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Amarillo to Tupelo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Rick Husband Amarillo Intl. Airport (AMA) to Tupelo Regional Airport (TUP) cost?
Grab a cheap one-way flight from $221 or cheap return flight from $437 from Rick Husband Amarillo Intl. Airport (AMA) to Tupelo Regional Airport (TUP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Rick Husband Amarillo Intl. Airport (AMA) to Tupelo Regional Airport (TUP)?
February is the least expensive month to fly from AMA to TUP. Traveling outside of peak seasons is often the key to finding better fares.
What is the cheapest airline that flies from Rick Husband Amarillo Intl. Airport (AMA) to Tupelo Regional Airport (TUP)?
To find the cheapest airline flying from AMA to TUP, use Expedia's filter tool. Customize your search based on what matters most to you, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Rick Husband Amarillo Intl. Airport (AMA) to Tupelo Regional Airport (TUP)?
There aren't any daily direct flights departing from Rick Husband Amarillo Intl. Airport (AMA) to Tupelo Regional Airport (TUP). But you can opt for flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be soaring above the clouds in no time at all.
What day of the week has the most flights from AMA to TUP?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Rick Husband Amarillo Intl. Airport (AMA) to Tupelo Regional Airport (TUP)?
Opt for a flight from Rick Husband Amarillo Intl. Airport (AMA) to Tupelo Regional Airport (TUP) that leaves before 3 PM to reduce the likelihood of delays and cancellations. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Rick Husband Amarillo Intl. Airport (AMA) to Tupelo Regional Airport (TUP) last-minute?
Last-minute bookings from AMA to TUP are usually more expensive. To lock in the best rates, start looking for flights ahead of time. That being said, if you're flexible with your travel plans, you may score a cheap fare right before you leave.
Is it cheaper to book an AMA to TUP flight and hotel package?
Compared with arranging hotels and flights separately, booking an AMA to TUP flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one place will take the hassle out of planning your trip. Just secure your flights and select from our wide range of hotels, then customize your trip with other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from Rick Husband Amarillo Intl. Airport (AMA) to Tupelo Regional Airport (TUP)?
If you booked your AMA to TUP flight within the last 24 hours, you may be able to cancel or modify it without any fees. Depending on the airline and the fare type you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for more details.

*Flight schedules are subject to change.

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*Available to One Key members.