$954 Cheap Flights from Brussels (BRU) to São Tomé Island (TMS)

View $954 flight on Sun, Mar 29, 2026Opens in a new window

Popular airlines from Brussels Airport (BRU) to São Tomé Island (TMS-São Tomé Intl.)

Cheap Flights from Brussels to São Tomé Island (BRU-TMS)

Prices were available within the past 7 days and start at $954 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Flights from Brussels (BRU) to São Tomé Island (TMS)
Origin airport
Brussels - National
Destination airport
São Tomé Intl.
Distance
3492 mi

Brussels to São Tomé Island Flights

The cheapest times to fly from Brussels to São Tomé Island

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Brussels to São Tomé Island are during the month of . You can find some of the cheapest flights from Brussels to São Tomé Island with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Brussels to São Tomé Island

Sunday is one of the best days to book for cheap flights from Brussels to São Tomé Island: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Brussels to São Tomé Island

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Brussels to São Tomé Island in 2025. You can also book with separate airlines for your outbound and return journeys, from $954 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Brussels to São Tomé Island flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Brussels to São Tomé Island airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Brussels - National Airport (BRU) to Sao Tome Intl. Airport (TMS) cost?
Lock in a cheap one-way flight from $954 or cheap return flight from Brussels - National Airport (BRU) to Sao Tome Intl. Airport (TMS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Brussels - National Airport (BRU) to Sao Tome Intl. Airport (TMS)?
Planning your trip for is a great way to save, as it's the cheapest month for flights between BRU and TMS. You'll often find the lowest prices during the off-season.
What is the cheapest airline that flies from Brussels - National Airport (BRU) to Sao Tome Intl. Airport (TMS)?
To find the cheapest airline flying from BRU to TMS, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Brussels - National Airport (BRU) to Sao Tome Intl. Airport (TMS)?
You'll have to catch a flight with a layover if you're traveling from Brussels - National Airport (BRU) to Sao Tome Intl. Airport (TMS). There are no daily direct flights on this route. However, just filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from BRU to TMS?
You'll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Brussels - National Airport (BRU) to Sao Tome Intl. Airport (TMS)?
To avoid potential delays on the Brussels - National Airport (BRU) to Sao Tome Intl. Airport (TMS) route, aim to fly before 3 PM. Flights after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Brussels - National Airport (BRU) to Sao Tome Intl. Airport (TMS) last-minute?
Last-minute bookings from BRU to TMS are typically more expensive. For the best prices, start looking for flights as early as possible. That said, if you're flexible with your travel plans, you may score a cheap ticket right before your journey.
Is it cheaper to book a BRU to TMS flight and hotel package?
Booking a BRU to TMS flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Choose from our extensive range of accommodations and then add car rentals, activities and flights to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Brussels - National Airport (BRU) to Sao Tome Intl. Airport (TMS)?
If you reserved your BRU to TMS flight within the last 24 hours, you may be able to cancel or modify it at no cost. Depending on the airline and the ticket type you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you want more information.

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*Available to One Key members.