$143 Cheap Flights from Buffalo (BUF) to Tucson (TUS)

Buffalo (BUF) to Tucson (TUS) at a glance

Travel between Buffalo (BUF) and Tucson (TUS) with a variety of airlines operating this domestic short-haul route. Discover options for cheap Buffalo to Tucson flights, whether you prefer full-service or low-cost carriers, to find the best match for your travel budget and schedule. As you plan your visit, take the time to explore Tucson’s renowned attractions and vibrant neighborhoods. Here are the essential details for your journey from Buffalo Niagara International Airport to Tucson International Airport.

• Fastest flight duration: around 6 hours in-flight, plus roughly 1h 15m layover with one stop
• Route distance: roughly 1,900 miles (3,060 km)
• Flights per week: around 8 departures on average
• Typical fares (one-way): economy tickets often range from $155–$515, depending on seasonality and how far ahead you book

Flights from Buffalo Niagara International Airport (BUF) to Tucson International Airport (TUS)

According to recent traveler bookings, the top airlines flying from Buffalo to Tucson are favored for their one-stop and multi-stop options. Common layover points include O'Hare International Airport (ORD) with a layover of about 1 hour and 15 minutes, Dallas-Fort Worth International Airport (DFW) with a 1-hour layover, and Denver International Airport (DEN) also offering a 1 hour and 15 minutes layover. These choices allow travelers to balance price, overall travel time, and cabin class for the ideal itinerary.

• American Airlines: A comprehensive carrier that provides both one-stop and multi-stop options, its one-way fares generally fall between $155 and $465. This airline represents around 41% of the departures on this route, with a typical in-flight duration of 6 hours and an overall travel time of approximately 7 hours and 15 minutes.
• United: As a full-service airline, United offers one-stop travel with one-way ticket prices usually ranging from $165 to $540. It accounts for about 28% of the flights on this route, featuring an in-air time of 6 hours and a total journey length of around 7 hours and 15 minutes, including layovers.
• Southwest Airlines: This low-cost airline delivers both one-stop and multi-stop services, with one-way fares falling between $155 and $535. Southwest handles roughly 19% of the departures on this route, with a standard in-flight duration of 6 hours and an estimated total travel time of about 7 hours and 15 minutes.
• Delta: Operating as a full-service carrier, Delta provides one-stop flights with one-way fare ranges typically from $155 to $415. It comprises about 12% of the route's departures and features an in-flight duration of 6 hours, resulting in a total journey time of roughly 7 hours and 15 minutes, including layover periods.

Best time to fly from Buffalo (BUF) to Tucson (TUS)

The most popular months for travelers flying from Buffalo to Tucson are February, March, and April, when peak temperatures in Tucson reach up to 68.9°F in April. If you prefer quieter travel, consider December, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 51.6°F. For better deals, August usually offers the lowest average one-way fare around $189. Flight availability peaks in November, with approximately 10 flights per week, making it easier to find convenient departure times. September has the fewest flights, with approximately 7 flights per week.

• Cheapest time to fly: August usually offers good deals with average one-way fare around $189, roughly 29% cheaper than the yearly average.
• Most flight options: November has the highest number of flights from Buffalo to Tucson, with approximately 10 flights per week, giving you more flexibility in scheduling your trip.

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative route from Buffalo (BUF) to Tucson (TUS)

• Rochester to Tucson (ROC-TUS): Greater Rochester International Airport (ROC) is located approximately 56 miles from Buffalo Niagara International Airport (BUF). One-way economy ticket prices for this route generally fall between $155 and $465, influenced by the season and advance booking. Travelers can choose from both one-stop and multi-stop flights, with common layover points including O'Hare International Airport (ORD) and Hartsfield-Jackson Atlanta International Airport (ATL). Major airlines operating on this route include American Airlines and United, with first-class service also offered.

How to find the best prices for flights from Buffalo (BUF) to Tucson (TUS)

Getting some of the best deals on flights from Buffalo to Tucson is all about timing and flexibility. Here are some key tips to help you save:

1. Best times to book and fly: cheaper fares are typically found when booking at least two months in advance, although most travelers book between two to eight weeks ahead. Evening departures from 6 PM to 12 AM tend to offer lower prices, while morning flights from 5 AM to 12 PM are the most popular. Additionally, flying on Wednesday generally offers cheaper prices, while Thursday is the most favored travel day.
2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Tucson International Airport from Buffalo Niagara International Airport

Tucson welcomes travelers from Buffalo with a range of transport options based on price, convenience, and proximity. Here's how to reach Tucson efficiently:

• Hotel transfer: Transfers offer a convenient way to reach your hotel in Tucson, with private rides that can be arranged in advance.
• Car rental: Renting a car from Tucson International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Tucson International Airport on Expedia.
• Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
• Public transportation: From Tucson International Airport, several key transport options are accessible by car: Roy Laos Transit Center, a metro station, is located about 5.2 miles away, while Tucson Station, a train station, is about 8.2 miles from the airport, and Ronstadt Transit Center, a bus station, is approximately 8.4 miles away.

Buffalo to Tucson Flights

The cheapest times to fly from Buffalo to Tucson

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Buffalo to Tucson are during the month of November. You can find some of the cheapest flights from Buffalo to Tucson with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Buffalo to Tucson

Sunday is one of the best days to book for cheap flights from Buffalo to Tucson: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Buffalo to Tucson

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Buffalo to Tucson in 2026. You can also book with separate airlines for your outbound and return journeys, from $143 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Buffalo to Tucson flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Buffalo to Tucson airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.