Cheap Flights from Charleston (CHS) to St. Louis (XLS)

Popular airlines from Charleston Intl. Airport (CHS) to St. Louis (XLS)

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Frequently asked questions

How much does a flight from Charleston Intl. Airport (CHS) to St. Louis (XLS) cost?
Get a cheap one-way flight or cheap return flight from Charleston Intl. Airport (CHS) to St. Louis (XLS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Charleston Intl. Airport (CHS) to St. Louis (XLS)?
Planning your getaway for is a great way to save, as it's the cheapest month for flights between CHS and XLS. You'll often find the lowest prices during the off-season.
What is the cheapest airline that flies from Charleston Intl. Airport (CHS) to St. Louis (XLS)?
To find the cheapest airline that'll fly you from CHS to XLS, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and number of stops. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Charleston Intl. Airport (CHS) to St. Louis (XLS)?
Nonstop flights from Charleston Intl. Airport (CHS) to St. Louis (XLS) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel details and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from CHS to XLS?
Generally you'll find the widest variety of flight choices on a Friday. Tuesdays are often the quietest.* However, this can vary based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Charleston Intl. Airport (CHS) to St. Louis (XLS)?
To avoid possible delays on the Charleston Intl. Airport (CHS) to St. Louis (XLS) route, aim to travel before 3 PM. Flights after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Charleston Intl. Airport (CHS) to St. Louis (XLS) last-minute?
Last-minute fares from CHS to XLS are usually more expensive. For the cheapest rates, start looking for flights well ahead of time. That being said, if your travel plans are flexible, it's possible to land a cheap fare right before you leave.
Is it cheaper to book a CHS to XLS flight and hotel package?
Compared with arranging hotels and flights separately, booking a CHS to XLS flight and hotel package with Expedia could result in significant savings. What's more, having everything in one place will take the hassle out of travel planning. Just secure your flights and choose from our extensive range of stays, then tailor your trip with other add-ons like car rentals and activities.
Can I cancel or change the date of my flight from Charleston Intl. Airport (CHS) to St. Louis (XLS)?
If you booked your CHS to XLS flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more information.

Travel information

Origin airport
Charleston Intl.
Destination airport
St. Louis
Distance
4103 mi

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Charleston to St. Louis Flights

The cheapest times to fly from Charleston to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Charleston to St. Louis are during the month of . You can find some of the cheapest flights from Charleston to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Charleston to St. Louis

Sunday is one of the best days to book for cheap flights from Charleston to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Charleston to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Charleston to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Charleston to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Charleston to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Charleston to St. Louis Flights

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*Available to One Key members.