$419 Cheap Flights from Des Moines (DSM) to Pisa (PSA)

View $419 flight on Mon, Sep 14, 2026Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Galileo Galilei Airport (PSA)

Cheap Flights from Des Moines to Pisa (DSM-PSA)

Prices were available within the past 7 days and start at $419 for one-way flights and $752 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, Sep 3 - Thu, Sep 10
DSM
Des Moines
PSA
Pisa
$752 Roundtrip, found 18 hours ago
$752
Roundtrip
found 18 hours ago
Select Delta flight, departing Thu, Sep 3 from Des Moines to Pisa, returning Thu, Sep 10, priced at $752 found 18 hours ago
British Airways
Mon, Apr 20 - Mon, Apr 27
DSM
Des Moines
PSA
Pisa
$761 Roundtrip, found 5 days ago
$761
Roundtrip
found 5 days ago
Select British Airways flight, departing Mon, Apr 20 from Des Moines to Pisa, returning Mon, Apr 27, priced at $761 found 5 days ago
British Airways
Wed, Nov 4 - Thu, Nov 12
DSM
Des Moines
PSA
Pisa
$775 Roundtrip, found 6 days ago
$775
Roundtrip
found 6 days ago
Select British Airways flight, departing Wed, Nov 4 from Des Moines to Pisa, returning Thu, Nov 12, priced at $775 found 6 days ago
British Airways
Sun, May 3 - Tue, May 19
DSM
Des Moines
PSA
Pisa
$831 Roundtrip, found 6 days ago
$831
Roundtrip
found 6 days ago
Select British Airways flight, departing Sun, May 3 from Des Moines to Pisa, returning Tue, May 19, priced at $831 found 6 days ago
British Airways
Thu, Apr 16 - Mon, Apr 20
DSM
Des Moines
PSA
Pisa
$844 Roundtrip, found 2 hours ago
$844
Roundtrip
found 2 hours ago
Select British Airways flight, departing Thu, Apr 16 from Des Moines to Pisa, returning Mon, Apr 20, priced at $844 found 2 hours ago
British Airways
Mon, Apr 20 - Mon, Apr 27
DSM
Des Moines
PSA
Pisa
$876 Roundtrip, found 5 days ago
$876
Roundtrip
found 5 days ago
Select British Airways flight, departing Mon, Apr 20 from Des Moines to Pisa, returning Mon, Apr 27, priced at $876 found 5 days ago
British Airways
Wed, May 6 - Tue, May 19
DSM
Des Moines
PSA
Pisa
$882 Roundtrip, found 6 days ago
$882
Roundtrip
found 6 days ago
Select British Airways flight, departing Wed, May 6 from Des Moines to Pisa, returning Tue, May 19, priced at $882 found 6 days ago
American Airlines
Thu, Sep 3 - Thu, Sep 10
DSM
Des Moines
PSA
Pisa
$911 Roundtrip, found 18 hours ago
$911
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Thu, Sep 3 from Des Moines to Pisa, returning Thu, Sep 10, priced at $911 found 18 hours ago
United
Mon, May 4 - Tue, May 19
DSM
Des Moines
PSA
Pisa
$939 Roundtrip, found 6 days ago
$939
Roundtrip
found 6 days ago
Select United flight, departing Mon, May 4 from Des Moines to Pisa, returning Tue, May 19, priced at $939 found 6 days ago
KLM
Mon, May 4 - Mon, May 18
DSM
Des Moines
PSA
Pisa
$984 Roundtrip, found 6 days ago
$984
Roundtrip
found 6 days ago
Select KLM flight, departing Mon, May 4 from Des Moines to Pisa, returning Mon, May 18, priced at $984 found 6 days ago

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Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Galileo Galilei Airport (PSA) cost?
Snag a cheap one-way flight from $419 or cheap return flight from $752 from Des Moines Intl. Airport (DSM) to Galileo Galilei Airport (PSA) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Galileo Galilei Airport (PSA)?
Planning your trip for September is a good way to save, as it's the cheapest month for flights between DSM and PSA. You'll often find the lowest fares during off-peak months.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Galileo Galilei Airport (PSA)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest DSM to PSA flight.
How many flights per day from Des Moines Intl. Airport (DSM) to Galileo Galilei Airport (PSA)?
There are no daily direct flights available from Des Moines Intl. Airport (DSM) to Galileo Galilei Airport (PSA). But you can choose flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be on your way before you know it.
What day of the week has the most flights from DSM to PSA?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can change depending on various factors, such as the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Galileo Galilei Airport (PSA)?
To land at Galileo Galilei Airport (PSA) on schedule, book a flight that leaves Des Moines Intl. Airport (DSM) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Galileo Galilei Airport (PSA) last-minute?
Holding off until right before your break to book your flight from DSM to PSA often results in higher prices. While you may find some last-minute discounts, there's no guarantee. Allow some flexibility in your schedule for a better chance of landing a bargain.
Is it cheaper to book a DSM to PSA flight and hotel package?
You can save money by booking a DSM to PSA flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one place. After choosing your ideal flights and accommodations, consider adding extras including tours, car rentals and activities.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Galileo Galilei Airport (PSA)?
Generally, it's possible to cancel or reschedule your DSM to PSA flight. However, for bookings made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
Des Moines Intl.
Destination airport
Galileo Galilei
Airlines serving
American Airlines, British Airways, KLM, United
Roundtrip price
$752
Distance
4900 mi

Book with confidence

Des Moines to Pisa Flights

The cheapest times to fly from Des Moines to Pisa

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Pisa are during the month of September. You can find some of the cheapest flights from Des Moines to Pisa with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Pisa

Sunday is one of the best days to book for cheap flights from Des Moines to Pisa: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Pisa

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Pisa in 2026. You can also book with separate airlines for your outbound and return journeys, from $419 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Pisa flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Pisa airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Des Moines to Pisa Flights

*Flight schedules are subject to change.

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*Available to One Key members.