$257 Cheap Flights from Des Moines (DSM) to Tri-Cities (TRI)

View $257 flight on Wed, Jul 1, 2026Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Tri-Cities, TN (TRI-Tri-Cities Regional)

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Cheap Flights from Des Moines to Tri-Cities (DSM-TRI)

Prices were available within the past 7 days and start at $257 for one-way flights and $309 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Thu, Jul 16 - Thu, Jul 23
DSM
Des Moines
TRI
Tri-Cities
$309 Roundtrip, found 1 day ago
$309
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Jul 16 from Des Moines to Tri-Cities, returning Thu, Jul 23, priced at $309 found 1 day ago
Delta
Wed, Aug 12 - Tue, Aug 18
DSM
Des Moines
TRI
Tri-Cities
$319 Roundtrip, found 1 day ago
$319
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Aug 12 from Des Moines to Tri-Cities, returning Tue, Aug 18, priced at $319 found 1 day ago
American Airlines
Wed, Jul 15 - Tue, Jul 21
DSM
Des Moines
TRI
Tri-Cities
$344 Roundtrip, found 1 day ago
$344
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Jul 15 from Des Moines to Tri-Cities, returning Tue, Jul 21, priced at $344 found 1 day ago
American Airlines
Wed, Jun 24 - Sat, Jun 27
DSM
Des Moines
TRI
Tri-Cities
$349 Roundtrip, found 2 days ago
$349
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Jun 24 from Des Moines to Tri-Cities, returning Sat, Jun 27, priced at $349 found 2 days ago
Delta
Fri, Sep 25 - Mon, Sep 28
DSM
Des Moines
TRI
Tri-Cities
$354 Roundtrip, found 1 day ago
$354
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Sep 25 from Des Moines to Tri-Cities, returning Mon, Sep 28, priced at $354 found 1 day ago
Delta
Wed, Aug 12 - Tue, Aug 18
DSM
Des Moines
TRI
Tri-Cities
$363 Roundtrip, found 1 day ago
$363
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Aug 12 from Des Moines to Tri-Cities, returning Tue, Aug 18, priced at $363 found 1 day ago
Delta
Wed, Jun 24 - Sat, Jun 27
DSM
Des Moines
TRI
Tri-Cities
$379 Roundtrip, found 2 days ago
$379
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, Jun 24 from Des Moines to Tri-Cities, returning Sat, Jun 27, priced at $379 found 2 days ago
American Airlines
Tue, Sep 22 - Sun, Sep 27
DSM
Des Moines
TRI
Tri-Cities
$383 Roundtrip, found 2 days ago
$383
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Sep 22 from Des Moines to Tri-Cities, returning Sun, Sep 27, priced at $383 found 2 days ago
American Airlines
Mon, Jul 6 - Mon, Aug 10
DSM
Des Moines
TRI
Tri-Cities
$388 Roundtrip, found 5 days ago
$388
Roundtrip
found 5 days ago
Select American Airlines flight, departing Mon, Jul 6 from Des Moines to Tri-Cities, returning Mon, Aug 10, priced at $388 found 5 days ago
American Airlines
Thu, Jul 16 - Thu, Jul 23
DSM
Des Moines
TRI
Tri-Cities
$389 Roundtrip, found 1 day ago
$389
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Jul 16 from Des Moines to Tri-Cities, returning Thu, Jul 23, priced at $389 found 1 day ago

What you need to know for your flight from Des Moines Intl. to Tri-Cities Regional

Des Moines (DSM) to Tri-Cities (TRI) at a glance

Traveling between Des Moines (DSM) and Tri-Cities (TRI) offers a range of airlines to choose from on this domestic short-haul route. Explore different options from full-service carriers to discover the itinerary that aligns best with your budget, schedule, and travel needs, all while visiting the iconic sights and neighborhoods of Tri-Cities. Check out the essential details for flights departing from Des Moines International Airport (DSM) to Tri-Cities Regional Airport (TRI).

  • Fastest flight duration: around 3h 30m in-flight, plus roughly 2h 15m layover with one stop
  • Route distance: roughly 700 miles (1,130 km)
  • Flights per week: around 7 departures on average
  • Typical fares (one-way): economy tickets often range from $180–$440, depending on seasonality and how far ahead you book

Flights from Des Moines International Airport (DSM) to Tri-Cities Regional Airport (TRI)

Based on recent traveler bookings, here are the top airlines favored for flights from Des Moines to Tri-Cities, primarily for their one-stop services. Common layover points include Charlotte-Douglas International Airport (CLT) with about a 2-hour wait, Hartsfield-Jackson Atlanta International Airport (ATL) with roughly a 3-hour layover, and Dallas-Fort Worth International Airport (DFW) with a shorter 55-minute layover. This variety allows you to balance price, overall travel time, and cabin class to secure the best itinerary.

  • American Airlines: This prominent full-service airline provides one-stop travel options, with one-way ticket prices generally falling between $180 and $445. It represents around 72% of flights on this route, featuring an in-flight duration of 3 hours and 30 minutes and a total travel time of about 5 hours and 45 minutes, including layover.
  • Delta: Another key full-service carrier, Delta offers one-stop service with one-way fares usually ranging from $215 to $480. It accounts for roughly 28% of departures for this route, with a similar in-flight time of 3 hours and 30 minutes and an overall journey length of approximately 5 hours and 45 minutes, inclusive of layover.

How to find the best prices for flights from Des Moines (DSM) to Tri-Cities (TRI)

Getting some of the best deals on flights from Des Moines to Tri-Cities is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually found when booking 2-8 weeks in advance, although most travelers tend to book within 2 weeks. Afternoon departures from 12pm to 6pm often offer lower prices, while morning flights from 5am to 12pm are the most popular. Additionally, flying on Saturday typically results in cheaper fares, though Thursday is the most favored travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Tri-Cities hotel and flight deals.
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Tri-Cities Regional Airport from Des Moines International Airport

Tri-Cities welcomes travelers from Des Moines with a range of transport options based on price, convenience, and proximity. Here's how to reach Tri-Cities efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Tri-Cities, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Tri-Cities Regional Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Tri-Cities Regional Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Tri-Cities Regional Airport, Tri-City Airport Seaport, a seaport, is located just 0.2 miles away on foot, providing easy access for travelers heading to the water.

Frequently asked questions

How much does a flight from Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional) cost?
You can find cheap one-way flights from $257 and cheap return flights from $309 Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional) with Expedia. One-way flights typically cost between $246 and $739, and return flights often range between $382 and $1355. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional)?
The cheapest month to fly from DSM to TRI is July when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional)?
Enter DSM to TRI and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional)?
American Airlines is one of the cheapest airlines offering connecting flights from Des Moines, IA (DSM) to Tri-Cities, TN (TRI) starting from around $289. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional)?
To find a cheap flight from Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional)?
The earliest flight from Des Moines International (DSM) to Tri-Cities Regional (TRI) typically leaves at around 5:00 AM, operated by American Airlines. This seasonal service is active in November, allowing you to make the most of your day upon arrival. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional)?
The most popular departure times for flights from Des Moines (DSM) to Tri-Cities (TRI) are in the late afternoon, from 3pm to 6pm. About 28% of passengers prefer this time window. Many major carriers, including American Airlines and Delta, offer flights during this period. This timing works well because it allows you to finish your day in Des Moines before heading out.
How long does it take to fly from Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional)?
A flight from DSM to TRI with a layover takes around 6 hours 20 minutes, with the route covering approximately 696 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional)?
First class seats are offered on the DSM to TRI route with American Airlines and Delta Air Lines.
How do I earn miles on a Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional) flight with Expedia?
It's easy to earn miles on a Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Tri-Cities from Des Moines Intl. (DSM)?
From Des Moines Intl. (DSM), you can fly into Tri-Cities Regional (TRI) to reach Tri-Cities. Some flights may connect through major hubs like O'Hare Intl. (ORD), George Bush Intercontinental (IAH), Denver Intl. (DEN) before reaching Tri-Cities. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional) at the last minute?
Typically, booking a last minute flight from Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional) flight and hotel package?
Securing a Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional)?
If you booked your Des Moines, IA (DSM-Des Moines Intl.) to Tri-Cities, TN (TRI-Tri-Cities Regional) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Des Moines Intl.
Destination airport
Tri-Cities Regional
Airlines serving
American Airlines, Delta
Roundtrip price
$308
Distance
696 mi

Book with confidence

Des Moines to Tri-Cities Flights

The cheapest times to fly from Des Moines to Tri-Cities

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Tri-Cities are during the month of July. You can find some of the cheapest flights from Des Moines to Tri-Cities with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Tri-Cities

Sunday is one of the best days to book for cheap flights from Des Moines to Tri-Cities: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Tri-Cities

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Tri-Cities in 2026. You can also book with separate airlines for your outbound and return journeys, from $257 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Tri-Cities flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Tri-Cities airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Des Moines to Tri-Cities Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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