$142 Cheap Flights from Istanbul (IST) to Milos (MLO)

View $142 flight on Mon, Oct 13, 2025Opens in a new window

Popular airlines from Istanbul Airport (IST) to Milos (MLO-Milos Island National)

Cheap Flights from Istanbul to Milos (IST-MLO)

Prices were available within the past 7 days and start at $142 for one-way flights and $359 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aegean
Fri, Oct 10 - Tue, Oct 14
IST
Istanbul
MLO
Milos
$359 Roundtrip, found 4 days ago
$359
Roundtrip
found 4 days ago
Select Aegean flight, departing Fri, Oct 10 from Istanbul to Milos, returning Tue, Oct 14, priced at $359 found 4 days ago
Aegean
Mon, Oct 13 - Mon, Oct 20
IST
Istanbul
MLO
Milos
$390 Roundtrip, found 3 days ago
$390
Roundtrip
found 3 days ago
Select Aegean flight, departing Mon, Oct 13 from Istanbul to Milos, returning Mon, Oct 20, priced at $390 found 3 days ago
Aegean
Thu, Oct 9 - Tue, Oct 14
IST
Istanbul
MLO
Milos
$390 Roundtrip, found 4 days ago
$390
Roundtrip
found 4 days ago
Select Aegean flight, departing Thu, Oct 9 from Istanbul to Milos, returning Tue, Oct 14, priced at $390 found 4 days ago
Aegean
Fri, Oct 10 - Tue, Oct 14
IST
Istanbul
MLO
Milos
$395 Roundtrip, found 4 days ago
$395
Roundtrip
found 4 days ago
Select Aegean flight, departing Fri, Oct 10 from Istanbul to Milos, returning Tue, Oct 14, priced at $395 found 4 days ago
Aegean
Mon, Oct 13 - Mon, Oct 20
IST
Istanbul
MLO
Milos
$405 Roundtrip, found 3 days ago
$405
Roundtrip
found 3 days ago
Select Aegean flight, departing Mon, Oct 13 from Istanbul to Milos, returning Mon, Oct 20, priced at $405 found 3 days ago
Aegean
Fri, Oct 10 - Tue, Oct 14
IST
Istanbul
MLO
Milos
$422 Roundtrip, found 4 days ago
$422
Roundtrip
found 4 days ago
Select Aegean flight, departing Fri, Oct 10 from Istanbul to Milos, returning Tue, Oct 14, priced at $422 found 4 days ago
Aegean
Mon, Oct 13 - Mon, Oct 20
IST
Istanbul
MLO
Milos
$425 Roundtrip, found 3 days ago
$425
Roundtrip
found 3 days ago
Select Aegean flight, departing Mon, Oct 13 from Istanbul to Milos, returning Mon, Oct 20, priced at $425 found 3 days ago
Aegean
Thu, Oct 9 - Tue, Oct 14
IST
Istanbul
MLO
Milos
$426 Roundtrip, found 4 days ago
$426
Roundtrip
found 4 days ago
Select Aegean flight, departing Thu, Oct 9 from Istanbul to Milos, returning Tue, Oct 14, priced at $426 found 4 days ago
SKY express
Mon, Oct 13 - Tue, Oct 21
IST
Istanbul
MLO
Milos
$482 Roundtrip, found 3 days ago
$482
Roundtrip
found 3 days ago
Select SKY express flight, departing Mon, Oct 13 from Istanbul to Milos, returning Tue, Oct 21, priced at $482 found 3 days ago
Hahn Air Systems
Fri, Oct 10 - Sun, Oct 19
IST
Istanbul
MLO
Milos
$706 Roundtrip, found 3 days ago
$706
Roundtrip
found 3 days ago
Select Hahn Air Systems flight, departing Fri, Oct 10 from Istanbul to Milos, returning Sun, Oct 19, priced at $706 found 3 days ago

Frequently asked questions

How much does a flight from Istanbul (IST) to Milos Island National Airport (MLO) cost?
Snag a cheap one-way flight from $142 or cheap return flight from $359 from Istanbul (IST) to Milos Island National Airport (MLO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Istanbul (IST) to Milos Island National Airport (MLO)?
The cheapest month to fly from IST to MLO is October, when there's less demand. Off-peak months are often when better flight deals are available between these airports.
What is the cheapest airline that flies from Istanbul (IST) to Milos Island National Airport (MLO)?
To find the cheapest airline flying from IST to MLO, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Istanbul (IST) to Milos Island National Airport (MLO)?
You'll have to hop on a flight with a layover if you're traveling from Istanbul (IST) to Milos Island National Airport (MLO). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from IST to MLO?
Generally you'll have the most choice when it comes to flights on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Istanbul (IST) to Milos Island National Airport (MLO)?
To avoid potential delays on the Istanbul (IST) to Milos Island National Airport (MLO) route, fly before 3 PM. Later departures have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Istanbul (IST) to Milos Island National Airport (MLO) last-minute?
Holding off until just before your trip to book your flight from IST to MLO generally means paying more. While you might find some last-minute deals, they're not always guaranteed. Keep your travel schedule open to maximize your chances of landing a bargain.
Is it cheaper to book an IST to MLO flight and hotel package?
You'll typically save money by securing an IST to MLO flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one convenient place. After choosing your ideal flights and accommodations, you can add extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Istanbul (IST) to Milos Island National Airport (MLO)?
Generally, it's possible to cancel or reschedule your IST to MLO flight. However, for bookings made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Travel information

Origin airport
Istanbul
Destination airport
Milos Island National
Roundtrip price
$358
Distance
389 mi

Book with confidence

Book with confidence

Istanbul to Milos Flights

The cheapest times to fly from Istanbul to Milos

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Istanbul to Milos are during the month of October. You can find some of the cheapest flights from Istanbul to Milos with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Istanbul to Milos

Sunday is one of the best days to book for cheap flights from Istanbul to Milos: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Istanbul to Milos

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Istanbul to Milos in 2025. You can also book with separate airlines for your outbound and return journeys, from $142 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Istanbul to Milos flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Istanbul to Milos airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Istanbul to Milos Flights

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*Available to One Key members.