$1,052 Cheap Flights from Las Vegas (LAS) to São Tomé Island (TMS)

View $1,052 flight on Mon, Sep 22, 2025Opens in a new window

Popular airlines from Harry Reid Intl. Airport (LAS) to São Tomé Island (TMS-São Tomé Intl.)

Cheap Flights from Las Vegas to São Tomé Island (LAS-TMS)

Prices were available within the past 7 days and start at $1,052 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Flights from Las Vegas (LAS) to São Tomé Island (TMS)
Origin airport
Harry Reid Intl.
Destination airport
São Tomé Intl.
Distance
7945 mi

Las Vegas to São Tomé Island Flights

The cheapest times to fly from Las Vegas to São Tomé Island

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Las Vegas to São Tomé Island are during the month of . You can find some of the cheapest flights from Las Vegas to São Tomé Island with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Las Vegas to São Tomé Island

Sunday is one of the best days to book for cheap flights from Las Vegas to São Tomé Island: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Las Vegas to São Tomé Island

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Las Vegas to São Tomé Island in 2025. You can also book with separate airlines for your outbound and return journeys, from $1,052 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Las Vegas to São Tomé Island flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Las Vegas to São Tomé Island airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Harry Reid Intl. Airport (LAS) to Sao Tome Intl. Airport (TMS) cost?
Get a cheap one-way flight from $1,052 or cheap return flight from Harry Reid Intl. Airport (LAS) to Sao Tome Intl. Airport (TMS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Harry Reid Intl. Airport (LAS) to Sao Tome Intl. Airport (TMS)?
Flying in may help you find better deals, as it's the cheapest month for flights between LAS and TMS. You'll typically find the lowest fares during off-peak months.
What is the cheapest airline that flies from Harry Reid Intl. Airport (LAS) to Sao Tome Intl. Airport (TMS)?
Use the filters on Expedia to compare different airlines and find the cheapest carrier that'll take you from LAS to TMS. Then, sort your results by "Price (lowest to highest)" to pick up a great deal.
How many flights per day from Harry Reid Intl. Airport (LAS) to Sao Tome Intl. Airport (TMS)?
Direct flights from Harry Reid Intl. Airport (LAS) to Sao Tome Intl. Airport (TMS) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your dates and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from LAS to TMS?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Harry Reid Intl. Airport (LAS) to Sao Tome Intl. Airport (TMS)?
To arrive at Sao Tome Intl. Airport (TMS) without delays, book a flight that leaves Harry Reid Intl. Airport (LAS) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Harry Reid Intl. Airport (LAS) to Sao Tome Intl. Airport (TMS) last-minute?
Waiting until just before your trip to book your flight from LAS to TMS generally means paying more. While you might find some last-minute deals, there's no guarantee. Keep your travel plans flexible for the best chance of getting a bargain.
Is it cheaper to book a LAS to TMS flight and hotel package?
Opting for a LAS to TMS flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Pick from our extensive range of accommodations and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Harry Reid Intl. Airport (LAS) to Sao Tome Intl. Airport (TMS)?
Usually, it's possible to cancel or reschedule your LAS to TMS flight. However, if it's been more than 24 hours since booking, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more information on our Customer Service portal.

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*Available to One Key members.