$209 Cheap Flights from Medellín (MDE) to Asuncion (ASU)

View $209 flight on Tue, Sep 9, 2025Opens in a new window

Popular airlines from Jose Maria Cordova Intl. Airport (MDE) to Asuncion (ASU-Silvio Pettirossi Intl.)

Cheap Flights from Medellín to Asuncion (MDE-ASU)

Prices were available within the past 7 days and start at $209 for one-way flights and $357 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Tue, Sep 30 - Tue, Oct 14
MDE
Medellin
ASU
Asuncion
$357 Roundtrip, found 3 days ago
$357
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Tue, Sep 30 from Medellin to Asuncion, returning Tue, Oct 14, priced at $357 found 3 days ago
LATAM Airlines Group
Wed, Oct 22 - Mon, Oct 27
MDE
Medellin
ASU
Asuncion
$357 Roundtrip, found 4 days ago
$357
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Wed, Oct 22 from Medellin to Asuncion, returning Mon, Oct 27, priced at $357 found 4 days ago
LATAM Airlines Group
Mon, Sep 1 - Mon, Sep 22
MDE
Medellin
ASU
Asuncion
$368 Roundtrip, found 3 days ago
$368
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Mon, Sep 1 from Medellin to Asuncion, returning Mon, Sep 22, priced at $368 found 3 days ago
Copa
Sun, Nov 9 - Tue, Nov 18
MDE
Medellin
ASU
Asuncion
$372 Roundtrip, found 19 hours ago
$372
Roundtrip
found 19 hours ago
Select Copa flight, departing Sun, Nov 9 from Medellin to Asuncion, returning Tue, Nov 18, priced at $372 found 19 hours ago
LATAM Airlines Group
Wed, Oct 1 - Tue, Oct 14
MDE
Medellin
ASU
Asuncion
$374 Roundtrip, found 3 days ago
$374
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Wed, Oct 1 from Medellin to Asuncion, returning Tue, Oct 14, priced at $374 found 3 days ago
LATAM Airlines Group
Thu, Oct 30 - Wed, Nov 12
MDE
Medellin
ASU
Asuncion
$379 Roundtrip, found 3 days ago
$379
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Thu, Oct 30 from Medellin to Asuncion, returning Wed, Nov 12, priced at $379 found 3 days ago
LATAM Airlines Group
Sat, Oct 11 - Wed, Oct 22
MDE
Medellin
ASU
Asuncion
$379 Roundtrip, found 3 days ago
$379
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Sat, Oct 11 from Medellin to Asuncion, returning Wed, Oct 22, priced at $379 found 3 days ago
Copa
Sun, Nov 9 - Tue, Nov 18
MDE
Medellin
ASU
Asuncion
$381 Roundtrip, found 19 hours ago
$381
Roundtrip
found 19 hours ago
Select Copa flight, departing Sun, Nov 9 from Medellin to Asuncion, returning Tue, Nov 18, priced at $381 found 19 hours ago
avianca
Sun, Nov 9 - Tue, Nov 18
MDE
Medellin
ASU
Asuncion
$416 Roundtrip, found 19 hours ago
$416
Roundtrip
found 19 hours ago
Select avianca flight, departing Sun, Nov 9 from Medellin to Asuncion, returning Tue, Nov 18, priced at $416 found 19 hours ago
Jetsmart SPA
Tue, Feb 3 - Sun, Feb 8
MDE
Medellin
ASU
Asuncion
$620 Roundtrip, found 5 days ago
$620
Roundtrip
found 5 days ago
Select Jetsmart SPA flight, departing Tue, Feb 3 from Medellin to Asuncion, returning Sun, Feb 8, priced at $620 found 5 days ago

Alternative airports near Asunción

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Silvio Pettirossi Intl. ASU. Cheapest and Closest option available. Average driving time to city center is 21 minutes. Flights from $733
ASU
Silvio Pettirossi Intl.
CheapestClosest
Average driving time to city center21 min
Flights from $733
Flights from Medellín (MDE) to Asuncion (ASU)
Origin airport
José María Córdova Intl.
Destination airport
Silvio Pettirossi Intl.
Airlines serving
Copa, LATAM Airlines Group, avianca
Roundtrip price
$356
Distance
2481 mi

Medellín to Asuncion Flights

The cheapest times to fly from Medellín to Asuncion

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Medellín to Asuncion are during the month of September. You can find some of the cheapest flights from Medellín to Asuncion with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Medellín to Asuncion

Sunday is one of the best days to book for cheap flights from Medellín to Asuncion: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Medellín to Asuncion

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Medellín to Asuncion in 2025. You can also book with separate airlines for your outbound and return journeys, from $209 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Medellín to Asuncion flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Medellín to Asuncion airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Jose Maria Cordova Intl. Airport (MDE) to Silvio Pettirossi Intl. Airport (ASU) cost?
Lock in a cheap one-way flight from $209 or cheap return flight from $357 from Jose Maria Cordova Intl. Airport (MDE) to Silvio Pettirossi Intl. Airport (ASU) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Jose Maria Cordova Intl. Airport (MDE) to Silvio Pettirossi Intl. Airport (ASU)?
Flying in September is a good way to save, as it's the cheapest month for flights between MDE and ASU. You'll typically find the lowest fares during the off-season.
What is the cheapest airline that flies from Jose Maria Cordova Intl. Airport (MDE) to Silvio Pettirossi Intl. Airport (ASU)?
Use the filter tool on Expedia to compare airlines and find the most affordable carrier that'll fly you from MDE to ASU. Then, sort your results by "Price (lowest to highest)" to snag a great deal.
How many flights per day from Jose Maria Cordova Intl. Airport (MDE) to Silvio Pettirossi Intl. Airport (ASU)?
There aren't any daily direct flights from Jose Maria Cordova Intl. Airport (MDE) to Silvio Pettirossi Intl. Airport (ASU). But you can opt for flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be on your way before you know it.
What day of the week has the most flights from MDE to ASU?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can change based on a number of factors, such as the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Jose Maria Cordova Intl. Airport (MDE) to Silvio Pettirossi Intl. Airport (ASU)?
To avoid possible delays on the Jose Maria Cordova Intl. Airport (MDE) to Silvio Pettirossi Intl. Airport (ASU) route, aim to fly before 3 PM. Later flights have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Jose Maria Cordova Intl. Airport (MDE) to Silvio Pettirossi Intl. Airport (ASU) last-minute?
Booking your plane ticket from MDE to ASU shortly before your journey is usually more expensive. However, if there's some wiggle room with your schedule, you could snag a cheap last-minute fare.
Is it cheaper to book a MDE to ASU flight and hotel package?
Securing a MDE to ASU flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Choose from our impressive range of hotels and then add activities, car rentals and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Jose Maria Cordova Intl. Airport (MDE) to Silvio Pettirossi Intl. Airport (ASU)?
It's generally possible to cancel or reschedule your MDE to ASU flight. However, if it's been more than 24 hours since booking, additional fees may apply. Check your airline's policies in your itinerary to see what changes are possible and if any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.