$222 Cheap Flights from Harrisburg (MDT) to Santo Domingo (SDQ)

View $222 flight on Thu, Aug 7, 2025Opens in a new window

Popular airlines from Harrisburg Intl. Airport (MDT) to Las Americas Intl. Airport (SDQ)

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Cheap Flights from Harrisburg to Santo Domingo (MDT-SDQ)

Prices were available within the past 7 days and start at $222 for one-way flights and $465 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Aug 19 - Fri, Sep 5
MDT
Harrisburg
SDQ
Santo Domingo
$465 Roundtrip, found 3 hours ago
$465
Roundtrip
found 3 hours ago
Select Delta flight, departing Tue, Aug 19 from Harrisburg to Santo Domingo, returning Fri, Sep 5, priced at $465 found 3 hours ago
Delta
Tue, Aug 19 - Mon, Sep 8
MDT
Harrisburg
SDQ
Santo Domingo
$466 Roundtrip, found 3 hours ago
$466
Roundtrip
found 3 hours ago
Select Delta flight, departing Tue, Aug 19 from Harrisburg to Santo Domingo, returning Mon, Sep 8, priced at $466 found 3 hours ago
Delta
Thu, Aug 21 - Mon, Sep 8
MDT
Harrisburg
SDQ
Santo Domingo
$467 Roundtrip, found 3 hours ago
$467
Roundtrip
found 3 hours ago
Select Delta flight, departing Thu, Aug 21 from Harrisburg to Santo Domingo, returning Mon, Sep 8, priced at $467 found 3 hours ago
American Airlines
Thu, Jul 31 - Thu, Aug 7
MDT
Harrisburg
SDQ
Santo Domingo
$469 Roundtrip, just found
$469
Roundtrip
just found
Select American Airlines flight, departing Thu, Jul 31 from Harrisburg to Santo Domingo, returning Thu, Aug 7, priced at $469 just found
Delta
Sat, Aug 30 - Tue, Sep 16
MDT
Harrisburg
SDQ
Santo Domingo
$470 Roundtrip, found 3 hours ago
$470
Roundtrip
found 3 hours ago
Select Delta flight, departing Sat, Aug 30 from Harrisburg to Santo Domingo, returning Tue, Sep 16, priced at $470 found 3 hours ago
American Airlines
Sun, Aug 24 - Tue, Aug 26
MDT
Harrisburg
SDQ
Santo Domingo
$471 Roundtrip, found 10 hours ago
$471
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Sun, Aug 24 from Harrisburg to Santo Domingo, returning Tue, Aug 26, priced at $471 found 10 hours ago
American Airlines
Thu, Oct 30 - Tue, Nov 4
MDT
Harrisburg
SDQ
Santo Domingo
$477 Roundtrip, found 4 days ago
$477
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Oct 30 from Harrisburg to Santo Domingo, returning Tue, Nov 4, priced at $477 found 4 days ago
American Airlines
Fri, Jul 4 - Sun, Jul 13
MDT
Harrisburg
SDQ
Santo Domingo
$480 Roundtrip, found 6 hours ago
$480
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Fri, Jul 4 from Harrisburg to Santo Domingo, returning Sun, Jul 13, priced at $480 found 6 hours ago
American Airlines
Sun, Oct 12 - Thu, Oct 30
MDT
Harrisburg
SDQ
Santo Domingo
$485 Roundtrip, found 14 hours ago
$485
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Sun, Oct 12 from Harrisburg to Santo Domingo, returning Thu, Oct 30, priced at $485 found 14 hours ago
United
Wed, Oct 29 - Wed, Nov 12
MDT
Harrisburg
SDQ
Santo Domingo
$490 Roundtrip, found 13 hours ago
$490
Roundtrip
found 13 hours ago
Select United flight, departing Wed, Oct 29 from Harrisburg to Santo Domingo, returning Wed, Nov 12, priced at $490 found 13 hours ago

Find the cheapest month to fly from Harrisburg (MDT) to Santo Domingo (SDQ)

February is typically the cheapest month to fly

From $340 - $682 per traveler.

Graph displaying average flight prices per month

Alternative airports near Santo Domingo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Las Americas Intl. SDQ. Cheapest option available. Average driving time to city center is 22 minutes. Flights from $684
SDQ
Las Americas Intl.
Cheapest
Average driving time to city center22 min
Flights from $684
Flights from Harrisburg (MDT) to Santo Domingo (SDQ)
Origin airport
Harrisburg Intl.
Destination airport
Las Americas Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$464
Distance
1561 mi

Harrisburg to Santo Domingo Flights

The cheapest times to fly from Harrisburg to Santo Domingo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Harrisburg to Santo Domingo are during the month of August. You can find some of the cheapest flights from Harrisburg to Santo Domingo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Harrisburg to Santo Domingo

Sunday is one of the best days to book for cheap flights from Harrisburg to Santo Domingo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Harrisburg to Santo Domingo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Harrisburg to Santo Domingo in 2025. You can also book with separate airlines for your outbound and return journeys, from $222 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Harrisburg to Santo Domingo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Harrisburg to Santo Domingo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Harrisburg Intl. Airport (MDT) to Las Americas Intl. Airport (SDQ) cost?
Discover the latest flight deals from MDT to SDQ by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from MDT to SDQ?
The cheapest flights from MDT to SDQ are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from MDT to SDQ?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from MDT to SDQ. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Harrisburg Intl. Airport (MDT) to Las Americas Intl. Airport (SDQ)?
You'll need to take a flight with a layover if you're traveling from Harrisburg Intl. Airport (MDT) to Las Americas Intl. Airport (SDQ). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from MDT to SDQ?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Harrisburg Intl. Airport (MDT) to Las Americas Intl. Airport (SDQ)?
To avoid potential delays on the Harrisburg Intl. Airport (MDT) to Las Americas Intl. Airport (SDQ) route, aim to fly before 3 PM. Departures after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Harrisburg Intl. Airport (MDT) to Las Americas Intl. Airport (SDQ) last-minute?
Last-minute bookings from MDT to SDQ are generally more expensive. To lock in the lowest rates, start looking for flights well in advance. That being said, if you're flexible with your travel plans, it's possible to score a cheap fare just before your departure.
Is it cheaper to book a MDT to SDQ flight and hotel package?
You'll typically save money by booking a MDT to SDQ flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one convenient place. After choosing your preferred flights and accommodations, you can add extras such as car rentals, tours and activities.
Can I cancel or change the date of my flight from Harrisburg Intl. Airport (MDT) to Las Americas Intl. Airport (SDQ)?
In most cases, you can cancel or modify your MDT to SDQ flight. However, additional charges may apply, especially if you booked over 24 hours ago. Check your itinerary for the airline's fees and rules on flight changes, or if you need further information, visit our Customer Service portal.

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*Available to One Key members.