$124 Cheap American Airlines flights Harrisburg (MDT) to Key West (EYW)

Make use of the “Price (lowest to highest)” filter on Expedia to look for cheap American Airlines round-trip flights from $218 from MDT to EYW. Affordable one-way options from $124 are also available.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

September is one of the cheapest months to jet off to Key West with American Airlines. You could also find excellent prices on one-way and return tickets in August.

To find cheap American Airlines fares from Harrisburg Intl. Airport (MDT) to Key West Intl. Airport (EYW), start searching one to three months before your intended departure. Reserving domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also affect what you pay. Sunday tends to be the cheapest, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your trip on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Enter your dates, hit search and use the “Nonstop” filter on Expedia to browse any direct flights from MDT to EYW with American Airlines or other carriers.

To find the earliest departures from MDT to EYW with American Airlines, filter your search by “Early Morning” and “Morning.” Choosing an early flight generally means you’ll experience fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Key West Intl. Airport (EYW) is the primary Key West gateway for American Airlines flights from Harrisburg Intl. Airport (MDT).

You can usually modify or cancel your flight, although there may be a charge if you made your booking more than 24 hours ago. Prefer to keep your options open? Make use of our “No cancel fee” and “Changes included” filters to find flights that won’t charge you extra if you need to adjust your plans. To modify your booking, visit “Trips,” select your flight and click on “Manage Booking” for more details.