$149 Cheap Flights from Harrisburg (MDT) to Santo Domingo (SDQ)

View $149 flight on Sat, Oct 4, 2025Opens in a new window

Popular airlines from Harrisburg Intl. Airport (MDT) to Las Americas Intl. Airport (SDQ)

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Cheap Flights from Harrisburg to Santo Domingo (MDT-SDQ)

Prices were available within the past 7 days and start at $149 for one-way flights and $325 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Oct 28 - Fri, Oct 31
MDT
Harrisburg
SDQ
Santo Domingo
$325 Roundtrip, found 4 days ago
$325
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Oct 28 from Harrisburg to Santo Domingo, returning Fri, Oct 31, priced at $325 found 4 days ago
American Airlines
Wed, Oct 8 - Mon, Oct 13
MDT
Harrisburg
SDQ
Santo Domingo
$325 Roundtrip, found 3 days ago
$325
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Oct 8 from Harrisburg to Santo Domingo, returning Mon, Oct 13, priced at $325 found 3 days ago
Delta
Sun, Nov 2 - Tue, Nov 18
MDT
Harrisburg
SDQ
Santo Domingo
$327 Roundtrip, found 4 days ago
$327
Roundtrip
found 4 days ago
Select Delta flight, departing Sun, Nov 2 from Harrisburg to Santo Domingo, returning Tue, Nov 18, priced at $327 found 4 days ago
American Airlines
Fri, Oct 3 - Sun, Oct 12
MDT
Harrisburg
SDQ
Santo Domingo
$330 Roundtrip, found 6 days ago
$330
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Oct 3 from Harrisburg to Santo Domingo, returning Sun, Oct 12, priced at $330 found 6 days ago
American Airlines
Sat, Nov 1 - Wed, Nov 5
MDT
Harrisburg
SDQ
Santo Domingo
$333 Roundtrip, found 3 days ago
$333
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Nov 1 from Harrisburg to Santo Domingo, returning Wed, Nov 5, priced at $333 found 3 days ago
American Airlines
Sat, Nov 1 - Wed, Nov 5
MDT
Harrisburg
SDQ
Santo Domingo
$334 Roundtrip, found 3 days ago
$334
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Nov 1 from Harrisburg to Santo Domingo, returning Wed, Nov 5, priced at $334 found 3 days ago
American Airlines
Sat, Oct 4 - Wed, Oct 8
MDT
Harrisburg
SDQ
Santo Domingo
$337 Roundtrip, found 4 days ago
$337
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Oct 4 from Harrisburg to Santo Domingo, returning Wed, Oct 8, priced at $337 found 4 days ago
Delta
Wed, Oct 29 - Wed, Nov 12
MDT
Harrisburg
SDQ
Santo Domingo
$340 Roundtrip, found 10 hours ago
$340
Roundtrip
found 10 hours ago
Select Delta flight, departing Wed, Oct 29 from Harrisburg to Santo Domingo, returning Wed, Nov 12, priced at $340 found 10 hours ago
United
Tue, Nov 18 - Thu, Nov 27
MDT
Harrisburg
SDQ
Santo Domingo
$354 Roundtrip, found 5 days ago
$354
Roundtrip
found 5 days ago
Select United flight, departing Tue, Nov 18 from Harrisburg to Santo Domingo, returning Thu, Nov 27, priced at $354 found 5 days ago
Frontier Airlines
Sat, Jan 10 - Sat, Jan 17
MDT
Harrisburg
SDQ
Santo Domingo
$465 Roundtrip, found 4 days ago
$465
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sat, Jan 10 from Harrisburg to Santo Domingo, returning Sat, Jan 17, priced at $465 found 4 days ago

Find the cheapest month to fly from Harrisburg (MDT) to Santo Domingo (SDQ)

February is typically the cheapest month to fly

From $366 - $682 per traveler.

Alternative airports near Santo Domingo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Las Americas Intl. SDQ. Cheapest option available. Average driving time to city center is 22 minutes. Flights from $501
SDQ
Las Americas Intl.
Cheapest
Average driving time to city center22 min
Flights from $501

Frequently asked questions

How much does a flight from Harrisburg Intl. Airport (MDT) to Las Americas Intl. Airport (SDQ) cost?
Grab a cheap one-way flight from $149 or cheap return flight from $325 from Harrisburg Intl. Airport (MDT) to Las Americas Intl. Airport (SDQ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Harrisburg Intl. Airport (MDT) to Las Americas Intl. Airport (SDQ)?
The cheapest month to fly from MDT to SDQ is October, when there's less demand. Off-peak months are usually when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Harrisburg Intl. Airport (MDT) to Las Americas Intl. Airport (SDQ)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find the carrier with the cheapest MDT to SDQ flight.
How many flights per day from Harrisburg Intl. Airport (MDT) to Las Americas Intl. Airport (SDQ)?
You'll need to take a flight with a layover if you're traveling from Harrisburg Intl. Airport (MDT) to Las Americas Intl. Airport (SDQ). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from MDT to SDQ?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Harrisburg Intl. Airport (MDT) to Las Americas Intl. Airport (SDQ)?
To avoid potential delays on the Harrisburg Intl. Airport (MDT) to Las Americas Intl. Airport (SDQ) route, aim to fly before 3 PM. Departures after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Harrisburg Intl. Airport (MDT) to Las Americas Intl. Airport (SDQ) last-minute?
Last-minute bookings from MDT to SDQ are generally more expensive. To lock in the lowest rates, start looking for flights well in advance. That being said, if you're flexible with your travel plans, it's possible to score a cheap fare just before your departure.
Is it cheaper to book a MDT to SDQ flight and hotel package?
You'll typically save money by booking a MDT to SDQ flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one convenient place. After choosing your preferred flights and accommodations, you can add extras such as car rentals, tours and activities.
Can I cancel or change the date of my flight from Harrisburg Intl. Airport (MDT) to Las Americas Intl. Airport (SDQ)?
In most cases, you can cancel or modify your MDT to SDQ flight. However, additional charges may apply, especially if you booked over 24 hours ago. Check your itinerary for the airline's fees and rules on flight changes, or if you need further information, visit our Customer Service portal.

Travel information

Travel information

Origin airport
Harrisburg Intl.
Destination airport
Las Americas Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, United
Roundtrip price
$324
Distance
1561 mi

Book with confidence

Book with confidence

Harrisburg to Santo Domingo Flights

The cheapest times to fly from Harrisburg to Santo Domingo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Harrisburg to Santo Domingo are during the month of October. You can find some of the cheapest flights from Harrisburg to Santo Domingo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Harrisburg to Santo Domingo

Sunday is one of the best days to book for cheap flights from Harrisburg to Santo Domingo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Harrisburg to Santo Domingo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Harrisburg to Santo Domingo in 2025. You can also book with separate airlines for your outbound and return journeys, from $149 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Harrisburg to Santo Domingo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Harrisburg to Santo Domingo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Harrisburg to Santo Domingo Flights

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*Available to One Key members.