$406 Cheap Flights from Chicago (MDW) to Leticia (LET)

View $406 flight on Mon, Nov 17, 2025Opens in a new window

Popular airlines from Chicago Midway Airport (MDW) to Leticia (LET-Vasquez Cobo Intl.)

Cheap Flights from Chicago to Leticia (MDW-LET)

Prices were available within the past 7 days and start at $406 for one-way flights and $946 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Mon, Nov 17 - Mon, Nov 24
MDW
Chicago
LET
Leticia
$946 Roundtrip, found 2 days ago
$946
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Mon, Nov 17 from Chicago to Leticia, returning Mon, Nov 24, priced at $946 found 2 days ago
LATAM Airlines Group
Mon, Nov 17 - Mon, Nov 24
MDW
Chicago
LET
Leticia
$1,046 Roundtrip, found 2 days ago
$1,046
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Mon, Nov 17 from Chicago to Leticia, returning Mon, Nov 24, priced at $1,046 found 2 days ago
Delta
Mon, Nov 17 - Mon, Nov 24
MDW
Chicago
LET
Leticia
$1,119 Roundtrip, found 2 days ago
$1,119
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Nov 17 from Chicago to Leticia, returning Mon, Nov 24, priced at $1,119 found 2 days ago
LATAM Airlines Group
Mon, Nov 17 - Mon, Nov 24
MDW
Chicago
LET
Leticia
$1,222 Roundtrip, found 2 days ago
$1,222
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Mon, Nov 17 from Chicago to Leticia, returning Mon, Nov 24, priced at $1,222 found 2 days ago
LATAM Airlines Group
Mon, Nov 17 - Mon, Nov 24
MDW
Chicago
LET
Leticia
$1,272 Roundtrip, found 2 days ago
$1,272
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Mon, Nov 17 from Chicago to Leticia, returning Mon, Nov 24, priced at $1,272 found 2 days ago
Delta
Mon, Nov 17 - Mon, Nov 24
MDW
Chicago
LET
Leticia
$1,284 Roundtrip, found 2 days ago
$1,284
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Nov 17 from Chicago to Leticia, returning Mon, Nov 24, priced at $1,284 found 2 days ago
LATAM Airlines Group
Mon, Nov 17 - Mon, Nov 24
MDW
Chicago
LET
Leticia
$1,335 Roundtrip, found 2 days ago
$1,335
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Mon, Nov 17 from Chicago to Leticia, returning Mon, Nov 24, priced at $1,335 found 2 days ago
LATAM Airlines Group
Mon, Nov 17 - Mon, Nov 24
MDW
Chicago
LET
Leticia
$1,610 Roundtrip, found 2 days ago
$1,610
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Mon, Nov 17 from Chicago to Leticia, returning Mon, Nov 24, priced at $1,610 found 2 days ago

Frequently asked questions

How much does a flight from Midway Intl. Airport (MDW) to Vasquez Cobo Intl. Airport (LET) cost?
Snag a cheap one-way flight from $406 or cheap return flight from $946 from Midway Intl. Airport (MDW) to Vasquez Cobo Intl. Airport (LET) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Midway Intl. Airport (MDW) to Vasquez Cobo Intl. Airport (LET)?
November is the most affordable month to fly from MDW to LET. Avoiding peak travel times is often the key to landing a great deal.
What is the cheapest airline that flies from Midway Intl. Airport (MDW) to Vasquez Cobo Intl. Airport (LET)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Select your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest MDW to LET flight.
How many flights per day from Midway Intl. Airport (MDW) to Vasquez Cobo Intl. Airport (LET)?
Nonstop flights from Midway Intl. Airport (MDW) to Vasquez Cobo Intl. Airport (LET) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel details and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MDW to LET?
You'll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Midway Intl. Airport (MDW) to Vasquez Cobo Intl. Airport (LET)?
To reach Vasquez Cobo Intl. Airport (LET) without delays, choose a flight that takes off from Midway Intl. Airport (MDW) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Midway Intl. Airport (MDW) to Vasquez Cobo Intl. Airport (LET) last-minute?
Booking your plane ticket from MDW to LET shortly before your trip is usually more expensive. But if there's some wiggle room with your travel times and dates, you could bag a cheap last-minute fare.
Is it cheaper to book a MDW to LET flight and hotel package?
Opting for a MDW to LET flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip all in one place. Pick from our wide range of hotels and then add activities, car rentals and flights to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Midway Intl. Airport (MDW) to Vasquez Cobo Intl. Airport (LET)?
Generally, it's possible to reschedule or cancel your MDW to LET flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Midway Intl.
Destination airport
Vasquez Cobo Intl.
Roundtrip price
$946
Distance
3368 mi

Book with confidence

Chicago to Leticia Flights

The cheapest times to fly from Chicago to Leticia

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Chicago to Leticia are during the month of November. You can find some of the cheapest flights from Chicago to Leticia with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Chicago to Leticia

Sunday is one of the best days to book for cheap flights from Chicago to Leticia: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Chicago to Leticia

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Chicago to Leticia in 2025. You can also book with separate airlines for your outbound and return journeys, from $406 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Chicago to Leticia flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Chicago to Leticia airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Chicago to Leticia Flights

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*Available to One Key members.