$125 Cheap Flights from Minneapolis (MSP) to Medellín (MDE)

View $125 flight on Thu, Nov 13, 2025Opens in a new window

Popular airlines from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Maria Cordova Intl. Airport (MDE)

    notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
    deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
    trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Minneapolis to Medellín (MSP-MDE)

Prices were available within the past 7 days and start at $125 for one-way flights and $337 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Sat, Oct 25 - Fri, Oct 31
MSP
Minneapolis
MDE
Medellin
$337 Roundtrip, found 4 days ago
$337
Roundtrip
found 4 days ago
Select Spirit Airlines flight, departing Sat, Oct 25 from Minneapolis to Medellin, returning Fri, Oct 31, priced at $337 found 4 days ago
Spirit Airlines
Mon, Oct 20 - Sat, Oct 25
MSP
Minneapolis
MDE
Medellin
$363 Roundtrip, found 1 day ago
$363
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Mon, Oct 20 from Minneapolis to Medellin, returning Sat, Oct 25, priced at $363 found 1 day ago
Spirit Airlines
Sat, Oct 11 - Thu, Oct 23
MSP
Minneapolis
MDE
Medellin
$366 Roundtrip, found 14 hours ago
$366
Roundtrip
found 14 hours ago
Select Spirit Airlines flight, departing Sat, Oct 11 from Minneapolis to Medellin, returning Thu, Oct 23, priced at $366 found 14 hours ago
Spirit Airlines
Mon, Oct 20 - Sun, Oct 26
MSP
Minneapolis
MDE
Medellin
$374 Roundtrip, found 1 day ago
$374
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Mon, Oct 20 from Minneapolis to Medellin, returning Sun, Oct 26, priced at $374 found 1 day ago
Spirit Airlines
Wed, Oct 15 - Thu, Oct 23
MSP
Minneapolis
MDE
Medellin
$379 Roundtrip, found 1 day ago
$379
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Wed, Oct 15 from Minneapolis to Medellin, returning Thu, Oct 23, priced at $379 found 1 day ago
Spirit Airlines
Wed, Oct 22 - Sun, Oct 26
MSP
Minneapolis
MDE
Medellin
$380 Roundtrip, found 6 days ago
$380
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Wed, Oct 22 from Minneapolis to Medellin, returning Sun, Oct 26, priced at $380 found 6 days ago
American Airlines
Thu, Jan 1 - Wed, Feb 25
MSP
Minneapolis
MDE
Medellin
$626 Roundtrip, found 1 hour ago
$626
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Thu, Jan 1 from Minneapolis to Medellin, returning Wed, Feb 25, priced at $626 found 1 hour ago
United
Wed, Nov 5 - Wed, Nov 19
MSP
Minneapolis
MDE
Medellin
$626 Roundtrip, found 1 hour ago
$626
Roundtrip
found 1 hour ago
Select United flight, departing Wed, Nov 5 from Minneapolis to Medellin, returning Wed, Nov 19, priced at $626 found 1 hour ago
Delta
Thu, Nov 6 - Tue, Nov 18
MSP
Minneapolis
MDE
Medellin
$638 Roundtrip, found 12 hours ago
$638
Roundtrip
found 12 hours ago
Select Delta flight, departing Thu, Nov 6 from Minneapolis to Medellin, returning Tue, Nov 18, priced at $638 found 12 hours ago
Copa
Thu, Oct 23 - Mon, Nov 3
MSP
Minneapolis
MDE
Medellin
$644 Roundtrip, found 4 days ago
$644
Roundtrip
found 4 days ago
Select Copa flight, departing Thu, Oct 23 from Minneapolis to Medellin, returning Mon, Nov 3, priced at $644 found 4 days ago

Find the cheapest month to fly from Minneapolis (MSP) to Medellín (MDE)

August is typically the cheapest month to fly

From $359 - $895 per traveler.
Flights from Minneapolis (MSP) to Medellín (MDE)
Origin airport
Minneapolis - St. Paul Intl.
Destination airport
José María Córdova Intl.
Airlines serving
Aeromexico, Air Canada, American Airlines, Copa, Delta, LATAM Airlines Group, Spirit Airlines, United, avianca
Roundtrip price
$336
Distance
2881 mi

Minneapolis to Medellín Flights

The cheapest times to fly from Minneapolis to Medellín

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Minneapolis to Medellín are during the month of October. You can find some of the cheapest flights from Minneapolis to Medellín with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Minneapolis to Medellín

Sunday is one of the best days to book for cheap flights from Minneapolis to Medellín: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Minneapolis to Medellín

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Minneapolis to Medellín in 2025. You can also book with separate airlines for your outbound and return journeys, from $125 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Minneapolis to Medellín flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Minneapolis to Medellín airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Maria Cordova Intl. Airport (MDE) cost?
Grab a cheap one-way flight from $125 or cheap return flight from $337 from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Maria Cordova Intl. Airport (MDE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Maria Cordova Intl. Airport (MDE)?
Planning your trip for October can help you save, as it's the cheapest month for flights between MSP and MDE. You'll often find the lowest fares during off-peak months.
What is the cheapest airline that flies from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Maria Cordova Intl. Airport (MDE)?
Use the filter tool on Expedia to compare airlines and find the most affordable carrier that'll fly you from MSP to MDE. Then, sort your results by "Price (lowest to highest)" to score the best deal available.
How many flights per day from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Maria Cordova Intl. Airport (MDE)?
Nonstop flights from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Maria Cordova Intl. Airport (MDE) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MSP to MDE?
You'll usually find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Maria Cordova Intl. Airport (MDE)?
To avoid possible delays on the Minneapolis - St. Paul Intl. Airport (MSP) to Jose Maria Cordova Intl. Airport (MDE) route, aim to fly before 3 PM. Departures after this time have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Maria Cordova Intl. Airport (MDE) last-minute?
Waiting until just before your departure to book a ticket from MSP to MDE generally means paying more. While it's possible to find some last-minute deals, they aren't always guaranteed. Be flexible with your itinerary for a better chance of scoring a bargain.
Is it cheaper to book a MSP to MDE flight and hotel package?
You'll generally save money by booking a MSP to MDE flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one place. Once you've selected your preferred accommodations and flights, you can add extras such as tours, activities and car rentals.
Can I cancel or change the date of my flight from Minneapolis - St. Paul Intl. Airport (MSP) to Jose Maria Cordova Intl. Airport (MDE)?
It's usually possible to cancel or reschedule your MSP to MDE flight. However, if it's been more than 24 hours since booking, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more details on our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.