$87 Cheap Flights from Myrtle Beach (MYR) to Medellín (MDE)

View $87 flight on Mon, Nov 10, 2025Opens in a new window

Popular airlines from Myrtle Beach Intl. Airport (MYR) to Jose Maria Cordova Intl. Airport (MDE)

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Cheap Flights from Myrtle Beach to Medellín (MYR-MDE)

Prices were available within the past 7 days and start at $87 for one-way flights and $309 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Thu, Nov 13 - Sat, Nov 15
MYR
Myrtle Beach
MDE
Medellin
$309 Roundtrip, found 5 days ago
$309
Roundtrip
found 5 days ago
Select Spirit Airlines flight, departing Thu, Nov 13 from Myrtle Beach to Medellin, returning Sat, Nov 15, priced at $309 found 5 days ago
Spirit Airlines
Fri, Nov 14 - Thu, Nov 20
MYR
Myrtle Beach
MDE
Medellin
$314 Roundtrip, found 4 days ago
$314
Roundtrip
found 4 days ago
Select Spirit Airlines flight, departing Fri, Nov 14 from Myrtle Beach to Medellin, returning Thu, Nov 20, priced at $314 found 4 days ago
Spirit Airlines
Fri, Nov 28 - Tue, Dec 9
MYR
Myrtle Beach
MDE
Medellin
$334 Roundtrip, found 2 days ago
$334
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Fri, Nov 28 from Myrtle Beach to Medellin, returning Tue, Dec 9, priced at $334 found 2 days ago
Spirit Airlines
Fri, Nov 7 - Mon, Nov 10
MYR
Myrtle Beach
MDE
Medellin
$348 Roundtrip, found 6 days ago
$348
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Fri, Nov 7 from Myrtle Beach to Medellin, returning Mon, Nov 10, priced at $348 found 6 days ago
Spirit Airlines
Fri, Nov 14 - Mon, Nov 17
MYR
Myrtle Beach
MDE
Medellin
$357 Roundtrip, found 9 hours ago
$357
Roundtrip
found 9 hours ago
Select Spirit Airlines flight, departing Fri, Nov 14 from Myrtle Beach to Medellin, returning Mon, Nov 17, priced at $357 found 9 hours ago
Spirit Airlines
Sun, Nov 2 - Fri, Nov 7
MYR
Myrtle Beach
MDE
Medellin
$359 Roundtrip, found 6 days ago
$359
Roundtrip
found 6 days ago
Select Spirit Airlines flight, departing Sun, Nov 2 from Myrtle Beach to Medellin, returning Fri, Nov 7, priced at $359 found 6 days ago
American Airlines
Sun, Nov 2 - Fri, Nov 7
MYR
Myrtle Beach
MDE
Medellin
$574 Roundtrip, found 6 days ago
$574
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sun, Nov 2 from Myrtle Beach to Medellin, returning Fri, Nov 7, priced at $574 found 6 days ago
Delta
Thu, Oct 30 - Fri, Nov 7
MYR
Myrtle Beach
MDE
Medellin
$580 Roundtrip, found 3 days ago
$580
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, Oct 30 from Myrtle Beach to Medellin, returning Fri, Nov 7, priced at $580 found 3 days ago
LATAM Airlines Group
Wed, Nov 12 - Mon, Nov 24
MYR
Myrtle Beach
MDE
Medellin
$667 Roundtrip, found 1 day ago
$667
Roundtrip
found 1 day ago
Select LATAM Airlines Group flight, departing Wed, Nov 12 from Myrtle Beach to Medellin, returning Mon, Nov 24, priced at $667 found 1 day ago
United
Sat, Nov 29 - Sun, Dec 14
MYR
Myrtle Beach
MDE
Medellin
$4,778 Roundtrip, found 1 day ago
$4,778
Roundtrip
found 1 day ago
Select United flight, departing Sat, Nov 29 from Myrtle Beach to Medellin, returning Sun, Dec 14, priced at $4,778 found 1 day ago

Alternative airports near Medellín

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Jose Maria Cordova Intl. MDE. Cheapest option available. Average driving time to city center is 29 minutes. Flights from $740
MDE
Jose Maria Cordova Intl.
Cheapest
Average driving time to city center29 min
Flights from $740
Flights from Myrtle Beach (MYR) to Medellín (MDE)
Origin airport
Myrtle Beach Intl.
Destination airport
José María Córdova Intl.
Airlines serving
LATAM Airlines Group, Spirit Airlines
Roundtrip price
$309
Distance
1913 mi

Myrtle Beach to Medellín Flights

The cheapest times to fly from Myrtle Beach to Medellín

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Myrtle Beach to Medellín are during the month of November. You can find some of the cheapest flights from Myrtle Beach to Medellín with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Myrtle Beach to Medellín

Sunday is one of the best days to book for cheap flights from Myrtle Beach to Medellín: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Myrtle Beach to Medellín

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Myrtle Beach to Medellín in 2025. You can also book with separate airlines for your outbound and return journeys, from $87 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Myrtle Beach to Medellín flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Myrtle Beach to Medellín airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Myrtle Beach Intl. Airport (MYR) to Jose Maria Cordova Intl. Airport (MDE) cost?
Get a cheap one-way flight from $87 or cheap return flight from $309 from Myrtle Beach Intl. Airport (MYR) to Jose Maria Cordova Intl. Airport (MDE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Myrtle Beach Intl. Airport (MYR) to Jose Maria Cordova Intl. Airport (MDE)?
November is the least expensive month to fly from MYR to MDE. Avoiding peak travel times is often the key to landing a great deal.
What is the cheapest airline that flies from Myrtle Beach Intl. Airport (MYR) to Jose Maria Cordova Intl. Airport (MDE)?
To find the cheapest airline that'll fly you from MYR to MDE, use Expedia's filter tool. Customize your search based on your travel style, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Myrtle Beach Intl. Airport (MYR) to Jose Maria Cordova Intl. Airport (MDE)?
You'll need to book a flight with a layover when traveling from Myrtle Beach Intl. Airport (MYR) to Jose Maria Cordova Intl. Airport (MDE). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from MYR to MDE?
You'll typically find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Myrtle Beach Intl. Airport (MYR) to Jose Maria Cordova Intl. Airport (MDE)?
To avoid possible delays on the Myrtle Beach Intl. Airport (MYR) to Jose Maria Cordova Intl. Airport (MDE) route, aim to travel before 3 PM. Later departures have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Myrtle Beach Intl. Airport (MYR) to Jose Maria Cordova Intl. Airport (MDE) last-minute?
Last-minute bookings from MYR to MDE are typically more expensive. To secure the best rates, start looking for flights early. That being said, if you're flexible with your travel dates, it's possible to find a cheap fare right before you leave.
Is it cheaper to book a MYR to MDE flight and hotel package?
Compared with arranging hotels and flights separately, booking a MYR to MDE flight and hotel package with Expedia could lead to significant savings. Better yet, having everything in one convenient place takes the hassle out of planning your trip. Simply pick your flights and select from our extensive range of hotels, then personalize your trip with extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Myrtle Beach Intl. Airport (MYR) to Jose Maria Cordova Intl. Airport (MDE)?
If you reserved your MYR to MDE flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for more information.

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*Available to One Key members.