$1,246 Cheap Flights from Philadelphia (PHL) to São Tomé Island (TMS)

View $1,246 flight on Wed, Nov 12, 2025Opens in a new window

Popular airlines from Philadelphia Intl. Airport (PHL) to São Tomé Island (TMS-São Tomé Intl.)

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Cheap Flights from Philadelphia to São Tomé Island (PHL-TMS)

Prices were available within the past 7 days and start at $1,246 for one-way flights and $2,156 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Wed, Nov 12 - Sun, Nov 16
PHL
Philadelphia
TMS
São Tomé Island
$2,156 Roundtrip, found 3 days ago
$2,156
Roundtrip
found 3 days ago
Select United flight, departing Wed, Nov 12 from Philadelphia to São Tomé Island, returning Sun, Nov 16, priced at $2,156 found 3 days ago
United
Wed, Nov 12 - Sun, Nov 16
PHL
Philadelphia
TMS
São Tomé Island
$2,160 Roundtrip, found 3 days ago
$2,160
Roundtrip
found 3 days ago
Select United flight, departing Wed, Nov 12 from Philadelphia to São Tomé Island, returning Sun, Nov 16, priced at $2,160 found 3 days ago
United
Wed, Nov 12 - Sun, Nov 16
PHL
Philadelphia
TMS
São Tomé Island
$2,163 Roundtrip, found 3 days ago
$2,163
Roundtrip
found 3 days ago
Select United flight, departing Wed, Nov 12 from Philadelphia to São Tomé Island, returning Sun, Nov 16, priced at $2,163 found 3 days ago
United
Wed, Nov 12 - Sun, Nov 16
PHL
Philadelphia
TMS
São Tomé Island
$2,167 Roundtrip, found 3 days ago
$2,167
Roundtrip
found 3 days ago
Select United flight, departing Wed, Nov 12 from Philadelphia to São Tomé Island, returning Sun, Nov 16, priced at $2,167 found 3 days ago
United
Wed, Nov 12 - Sun, Nov 16
PHL
Philadelphia
TMS
São Tomé Island
$2,171 Roundtrip, found 3 days ago
$2,171
Roundtrip
found 3 days ago
Select United flight, departing Wed, Nov 12 from Philadelphia to São Tomé Island, returning Sun, Nov 16, priced at $2,171 found 3 days ago
United
Wed, Nov 12 - Sun, Nov 16
PHL
Philadelphia
TMS
São Tomé Island
$2,172 Roundtrip, found 3 days ago
$2,172
Roundtrip
found 3 days ago
Select United flight, departing Wed, Nov 12 from Philadelphia to São Tomé Island, returning Sun, Nov 16, priced at $2,172 found 3 days ago
United
Wed, Nov 12 - Sun, Nov 16
PHL
Philadelphia
TMS
São Tomé Island
$2,175 Roundtrip, found 3 days ago
$2,175
Roundtrip
found 3 days ago
Select United flight, departing Wed, Nov 12 from Philadelphia to São Tomé Island, returning Sun, Nov 16, priced at $2,175 found 3 days ago
Ethiopian Airlines
Wed, Nov 12 - Sun, Nov 16
PHL
Philadelphia
TMS
São Tomé Island
$3,099 Roundtrip, found 3 days ago
$3,099
Roundtrip
found 3 days ago
Select Ethiopian Airlines flight, departing Wed, Nov 12 from Philadelphia to São Tomé Island, returning Sun, Nov 16, priced at $3,099 found 3 days ago
Ethiopian Airlines
Wed, Nov 12 - Sun, Nov 16
PHL
Philadelphia
TMS
São Tomé Island
$3,109 Roundtrip, found 3 days ago
$3,109
Roundtrip
found 3 days ago
Select Ethiopian Airlines flight, departing Wed, Nov 12 from Philadelphia to São Tomé Island, returning Sun, Nov 16, priced at $3,109 found 3 days ago
United
Wed, Nov 12 - Sun, Nov 16
PHL
Philadelphia
TMS
São Tomé Island
$3,115 Roundtrip, found 3 days ago
$3,115
Roundtrip
found 3 days ago
Select United flight, departing Wed, Nov 12 from Philadelphia to São Tomé Island, returning Sun, Nov 16, priced at $3,115 found 3 days ago
United
Wed, Nov 12 - Sun, Nov 16
PHL
Philadelphia
TMS
São Tomé Island
$3,125 Roundtrip, found 3 days ago
$3,125
Roundtrip
found 3 days ago
Select United flight, departing Wed, Nov 12 from Philadelphia to São Tomé Island, returning Sun, Nov 16, priced at $3,125 found 3 days ago
JetBlue Airways
Wed, Nov 12 - Sun, Nov 16
PHL
Philadelphia
TMS
São Tomé Island
$3,334 Roundtrip, found 3 days ago
$3,334
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Wed, Nov 12 from Philadelphia to São Tomé Island, returning Sun, Nov 16, priced at $3,334 found 3 days ago
JetBlue Airways
Wed, Nov 12 - Sun, Nov 16
PHL
Philadelphia
TMS
São Tomé Island
$3,365 Roundtrip, found 3 days ago
$3,365
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Wed, Nov 12 from Philadelphia to São Tomé Island, returning Sun, Nov 16, priced at $3,365 found 3 days ago
JetBlue Airways
Wed, Nov 12 - Sun, Nov 16
PHL
Philadelphia
TMS
São Tomé Island
$3,370 Roundtrip, found 3 days ago
$3,370
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Wed, Nov 12 from Philadelphia to São Tomé Island, returning Sun, Nov 16, priced at $3,370 found 3 days ago
JetBlue Airways
Wed, Nov 12 - Sun, Nov 16
PHL
Philadelphia
TMS
São Tomé Island
$3,401 Roundtrip, found 3 days ago
$3,401
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Wed, Nov 12 from Philadelphia to São Tomé Island, returning Sun, Nov 16, priced at $3,401 found 3 days ago
American Airlines
Wed, Nov 12 - Sun, Nov 16
PHL
Philadelphia
TMS
São Tomé Island
$3,449 Roundtrip, found 3 days ago
$3,449
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Nov 12 from Philadelphia to São Tomé Island, returning Sun, Nov 16, priced at $3,449 found 3 days ago

Frequently asked questions

How much does a flight from Philadelphia Intl. Airport (PHL) to Sao Tome Intl. Airport (TMS) cost?
Grab a cheap one-way flight from $1,246 or cheap return flight from $2,156 from Philadelphia Intl. Airport (PHL) to Sao Tome Intl. Airport (TMS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Philadelphia Intl. Airport (PHL) to Sao Tome Intl. Airport (TMS)?
Planning your getaway for November is a good way to save, as it's the cheapest month for flights between PHL and TMS. You'll usually find the lowest fares during off-peak months.
What is the cheapest airline that flies from Philadelphia Intl. Airport (PHL) to Sao Tome Intl. Airport (TMS)?
To find the cheapest airline flying from PHL to TMS, use Expedia's filter tool. Tailor your search based on what's important to you, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Philadelphia Intl. Airport (PHL) to Sao Tome Intl. Airport (TMS)?
Nonstop flights from Philadelphia Intl. Airport (PHL) to Sao Tome Intl. Airport (TMS) aren't available daily, so you'll have to take a flight with a layover. Explore your options with our filter tool. Enter your travel details and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from PHL to TMS?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can vary based on various factors, such as the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Philadelphia Intl. Airport (PHL) to Sao Tome Intl. Airport (TMS)?
To touch down at Sao Tome Intl. Airport (TMS) on schedule, choose a flight that takes off from Philadelphia Intl. Airport (PHL) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Philadelphia Intl. Airport (PHL) to Sao Tome Intl. Airport (TMS) last-minute?
Last-minute bookings from PHL to TMS are generally more expensive. To lock in the lowest rates, start looking for flights as early as possible. That being said, if you're flexible with your travel plans, you may land a cheap fare right before your trip.
Is it cheaper to book a PHL to TMS flight and hotel package?
Booking a PHL to TMS flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Choose from our wide range of stays and then add activities, car rentals and flights to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Philadelphia Intl. Airport (PHL) to Sao Tome Intl. Airport (TMS)?
If you booked your PHL to TMS flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for further details.

Travel information

Origin airport
Philadelphia Intl.
Destination airport
São Tomé Intl.
Roundtrip price
$2,155
Distance
5775 mi

Book with confidence

Philadelphia to São Tomé Island Flights

The cheapest times to fly from Philadelphia to São Tomé Island

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Philadelphia to São Tomé Island are during the month of November. You can find some of the cheapest flights from Philadelphia to São Tomé Island with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Philadelphia to São Tomé Island

Sunday is one of the best days to book for cheap flights from Philadelphia to São Tomé Island: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Philadelphia to São Tomé Island

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Philadelphia to São Tomé Island in 2025. You can also book with separate airlines for your outbound and return journeys, from $1,246 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Philadelphia to São Tomé Island flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Philadelphia to São Tomé Island airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Philadelphia to São Tomé Island Flights
*Available to One Key members.