$299 Cheap Flights from San Luis Obispo (SBP) to Medellín (MDE)

View $299 flight on Thu, Oct 9, 2025Opens in a new window

Popular airlines from San Luis Obispo County Regional Airport (SBP) to Jose Maria Cordova Intl. Airport (MDE)

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Cheap Flights from San Luis Obispo to Medellín (SBP-MDE)

Prices were available within the past 7 days and start at $299 for one-way flights and $557 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Tue, Oct 28 - Tue, Nov 11
SBP
San Luis Obispo
MDE
Medellin
$557 Roundtrip, found 3 days ago
$557
Roundtrip
found 3 days ago
Select United flight, departing Tue, Oct 28 from San Luis Obispo to Medellin, returning Tue, Nov 11, priced at $557 found 3 days ago
United
Tue, Oct 28 - Sat, Nov 8
SBP
San Luis Obispo
MDE
Medellin
$567 Roundtrip, found 3 days ago
$567
Roundtrip
found 3 days ago
Select United flight, departing Tue, Oct 28 from San Luis Obispo to Medellin, returning Sat, Nov 8, priced at $567 found 3 days ago
United
Tue, Nov 25 - Tue, Dec 9
SBP
San Luis Obispo
MDE
Medellin
$574 Roundtrip, found 3 days ago
$574
Roundtrip
found 3 days ago
Select United flight, departing Tue, Nov 25 from San Luis Obispo to Medellin, returning Tue, Dec 9, priced at $574 found 3 days ago
United
Fri, Oct 24 - Sat, Nov 8
SBP
San Luis Obispo
MDE
Medellin
$577 Roundtrip, found 3 days ago
$577
Roundtrip
found 3 days ago
Select United flight, departing Fri, Oct 24 from San Luis Obispo to Medellin, returning Sat, Nov 8, priced at $577 found 3 days ago
American Airlines
Thu, Oct 9 - Thu, Oct 23
SBP
San Luis Obispo
MDE
Medellin
$582 Roundtrip, found 15 hours ago
$582
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Thu, Oct 9 from San Luis Obispo to Medellin, returning Thu, Oct 23, priced at $582 found 15 hours ago
United
Tue, Nov 25 - Sat, Dec 6
SBP
San Luis Obispo
MDE
Medellin
$584 Roundtrip, found 3 days ago
$584
Roundtrip
found 3 days ago
Select United flight, departing Tue, Nov 25 from San Luis Obispo to Medellin, returning Sat, Dec 6, priced at $584 found 3 days ago
United
Tue, Oct 28 - Mon, Nov 3
SBP
San Luis Obispo
MDE
Medellin
$585 Roundtrip, found 3 days ago
$585
Roundtrip
found 3 days ago
Select United flight, departing Tue, Oct 28 from San Luis Obispo to Medellin, returning Mon, Nov 3, priced at $585 found 3 days ago
United
Sun, Oct 19 - Sat, Nov 1
SBP
San Luis Obispo
MDE
Medellin
$587 Roundtrip, found 3 days ago
$587
Roundtrip
found 3 days ago
Select United flight, departing Sun, Oct 19 from San Luis Obispo to Medellin, returning Sat, Nov 1, priced at $587 found 3 days ago
United
Mon, Oct 27 - Mon, Nov 10
SBP
San Luis Obispo
MDE
Medellin
$592 Roundtrip, found 3 days ago
$592
Roundtrip
found 3 days ago
Select United flight, departing Mon, Oct 27 from San Luis Obispo to Medellin, returning Mon, Nov 10, priced at $592 found 3 days ago
Copa
Fri, Oct 10 - Fri, Oct 24
SBP
San Luis Obispo
MDE
Medellin
$645 Roundtrip, found 1 day ago
$645
Roundtrip
found 1 day ago
Select Copa flight, departing Fri, Oct 10 from San Luis Obispo to Medellin, returning Fri, Oct 24, priced at $645 found 1 day ago

Alternative airports near Medellín

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Jose Maria Cordova Intl. MDE. Cheapest option available. Average driving time to city center is 29 minutes. Flights from $795
MDE
Jose Maria Cordova Intl.
Cheapest
Average driving time to city center29 min
Flights from $795
Flights from San Luis Obispo (SBP) to Medellín (MDE)
Origin airport
San Luis Obispo County Regional
Destination airport
José María Córdova Intl.
Airlines serving
American Airlines, Copa, United
Roundtrip price
$557
Distance
3499 mi

San Luis Obispo to Medellín Flights

The cheapest times to fly from San Luis Obispo to Medellín

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from San Luis Obispo to Medellín are during the month of October. You can find some of the cheapest flights from San Luis Obispo to Medellín with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from San Luis Obispo to Medellín

Sunday is one of the best days to book for cheap flights from San Luis Obispo to Medellín: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from San Luis Obispo to Medellín

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from San Luis Obispo to Medellín in 2025. You can also book with separate airlines for your outbound and return journeys, from $299 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap San Luis Obispo to Medellín flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your San Luis Obispo to Medellín airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from San Luis Obispo County Regional Airport (SBP) to Jose Maria Cordova Intl. Airport (MDE) cost?
Get a cheap one-way flight from $299 or cheap return flight from $557 from San Luis Obispo County Regional Airport (SBP) to Jose Maria Cordova Intl. Airport (MDE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from San Luis Obispo County Regional Airport (SBP) to Jose Maria Cordova Intl. Airport (MDE)?
October is the least expensive month to fly from SBP to MDE. Avoiding peak travel times is often the key to scoring lower fares.
What is the cheapest airline that flies from San Luis Obispo County Regional Airport (SBP) to Jose Maria Cordova Intl. Airport (MDE)?
Expedia's filter tool lets you easily compare different airlines, departure times and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest SBP to MDE flight.
How many flights per day from San Luis Obispo County Regional Airport (SBP) to Jose Maria Cordova Intl. Airport (MDE)?
Nonstop flights from San Luis Obispo County Regional Airport (SBP) to Jose Maria Cordova Intl. Airport (MDE) aren't available daily, so you'll have to take a flight with a layover. Explore your options with our filter tool. Enter your travel details and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from SBP to MDE?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Keep in mind that flight schedules can change based on a number of factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from San Luis Obispo County Regional Airport (SBP) to Jose Maria Cordova Intl. Airport (MDE)?
Choose a flight from San Luis Obispo County Regional Airport (SBP) to Jose Maria Cordova Intl. Airport (MDE) that leaves before 3 PM to reduce the likelihood of delays. Departures after this time have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from San Luis Obispo County Regional Airport (SBP) to Jose Maria Cordova Intl. Airport (MDE) last-minute?
Waiting until just before your departure to book a ticket from SBP to MDE generally means paying more. While you may come across some last-minute deals, there's no guarantee. Keep your travel schedule open for the best chance of scoring a bargain.
Is it cheaper to book a SBP to MDE flight and hotel package?
Compared with arranging hotels and flights separately, booking a SBP to MDE flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one place will take the hassle out of travel planning. Just secure your flights and select from our wide range of stays, then customize your trip with extras like car rentals and activities.
Can I cancel or change the date of my flight from San Luis Obispo County Regional Airport (SBP) to Jose Maria Cordova Intl. Airport (MDE)?
If you reserved your SBP to MDE flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you want more information.

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*Available to One Key members.