$123 Cheap Flights from Syracuse (SYR) to Medellín (MDE)

View $123 flight on Tue, Feb 17, 2026Opens in a new window

Popular airlines from Hancock Intl. Airport (SYR) to Jose Maria Cordova Intl. Airport (MDE)

Cheap Flights from Syracuse to Medellín (SYR-MDE)

Prices were available within the past 7 days and start at $123 for one-way flights and $293 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, Jan 23 - Tue, Mar 3
SYR
Syracuse
MDE
Medellin
$293 Roundtrip, found 3 days ago
$293
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Jan 23 from Syracuse to Medellin, returning Tue, Mar 3, priced at $293 found 3 days ago
American Airlines
Tue, Mar 17 - Sat, Mar 21
SYR
Syracuse
MDE
Medellin
$298 Roundtrip, found 1 day ago
$298
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Mar 17 from Syracuse to Medellin, returning Sat, Mar 21, priced at $298 found 1 day ago
American Airlines
Sat, Jan 31 - Mon, Mar 2
SYR
Syracuse
MDE
Medellin
$299 Roundtrip, found 19 hours ago
$299
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Sat, Jan 31 from Syracuse to Medellin, returning Mon, Mar 2, priced at $299 found 19 hours ago
United
Fri, Feb 20 - Wed, Feb 25
SYR
Syracuse
MDE
Medellin
$308 Roundtrip, found 1 day ago
$308
Roundtrip
found 1 day ago
Select United flight, departing Fri, Feb 20 from Syracuse to Medellin, returning Wed, Feb 25, priced at $308 found 1 day ago
American Airlines
Sun, Jan 18 - Sat, Jan 24
SYR
Syracuse
MDE
Medellin
$311 Roundtrip, found 6 days ago
$311
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sun, Jan 18 from Syracuse to Medellin, returning Sat, Jan 24, priced at $311 found 6 days ago
American Airlines
Wed, Feb 18 - Sun, Feb 22
SYR
Syracuse
MDE
Medellin
$316 Roundtrip, just found
$316
Roundtrip
just found
Select American Airlines flight, departing Wed, Feb 18 from Syracuse to Medellin, returning Sun, Feb 22, priced at $316 just found
United
Fri, Jan 23 - Wed, Mar 4
SYR
Syracuse
MDE
Medellin
$338 Roundtrip, found 3 days ago
$338
Roundtrip
found 3 days ago
Select United flight, departing Fri, Jan 23 from Syracuse to Medellin, returning Wed, Mar 4, priced at $338 found 3 days ago
Delta
Wed, Mar 4 - Tue, Mar 17
SYR
Syracuse
MDE
Medellin
$455 Roundtrip, found 6 days ago
$455
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Mar 4 from Syracuse to Medellin, returning Tue, Mar 17, priced at $455 found 6 days ago
LATAM Airlines Group
Wed, Feb 18 - Tue, Feb 24
SYR
Syracuse
MDE
Medellin
$485 Roundtrip, found 1 day ago
$485
Roundtrip
found 1 day ago
Select LATAM Airlines Group flight, departing Wed, Feb 18 from Syracuse to Medellin, returning Tue, Feb 24, priced at $485 found 1 day ago
avianca
Wed, Jan 14 - Fri, Jan 23
SYR
Syracuse
MDE
Medellin
$513 Roundtrip, found 6 days ago
$513
Roundtrip
found 6 days ago
Select avianca flight, departing Wed, Jan 14 from Syracuse to Medellin, returning Fri, Jan 23, priced at $513 found 6 days ago

Alternative airports near Medellín

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Jose Maria Cordova Intl. MDE. Cheapest option available. Average driving time to city center is 29 minutes. Flights from $902
MDE
Jose Maria Cordova Intl.
Cheapest
Average driving time to city center29 min
Flights from $902
Flights from Syracuse (SYR) to Medellín (MDE)
Origin airport
Hancock Intl.
Destination airport
José María Córdova Intl.
Airlines serving
American Airlines, Delta, JetBlue Airways, LATAM Airlines Group, United
Roundtrip price
$292
Distance
2552 mi

Syracuse to Medellín Flights

The cheapest times to fly from Syracuse to Medellín

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Syracuse to Medellín are during the month of January. You can find some of the cheapest flights from Syracuse to Medellín with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Syracuse to Medellín

Sunday is one of the best days to book for cheap flights from Syracuse to Medellín: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Syracuse to Medellín

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Syracuse to Medellín in 2026. You can also book with separate airlines for your outbound and return journeys, from $123 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Syracuse to Medellín flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Syracuse to Medellín airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Hancock Intl. Airport (SYR) to Jose Maria Cordova Intl. Airport (MDE) cost?
Lock in a cheap one-way flight from $123 or cheap return flight from $293 from Hancock Intl. Airport (SYR) to Jose Maria Cordova Intl. Airport (MDE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Hancock Intl. Airport (SYR) to Jose Maria Cordova Intl. Airport (MDE)?
The cheapest month to fly from SYR to MDE is January, when there's less demand. Off-peak season is generally when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Hancock Intl. Airport (SYR) to Jose Maria Cordova Intl. Airport (MDE)?
Use the filters on Expedia to compare different airlines and find the most affordable carrier that'll take you from SYR to MDE. Then, sort your results by "Price (lowest to highest)" to score the best deal available.
How many flights per day from Hancock Intl. Airport (SYR) to Jose Maria Cordova Intl. Airport (MDE)?
There are no daily nonstop flights from Hancock Intl. Airport (SYR) to Jose Maria Cordova Intl. Airport (MDE). But you can choose flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be soaring above the clouds in no time at all.
What day of the week has the most flights from SYR to MDE?
Typically you'll have the most choice when it comes to flights on a Friday. Tuesdays are often the quietest.* However, this can change depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Hancock Intl. Airport (SYR) to Jose Maria Cordova Intl. Airport (MDE)?
Choose a flight from Hancock Intl. Airport (SYR) to Jose Maria Cordova Intl. Airport (MDE) that takes off before 3 PM to reduce the risk of delays and cancellations. Departures later than this are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Hancock Intl. Airport (SYR) to Jose Maria Cordova Intl. Airport (MDE) last-minute?
Last-minute bookings from SYR to MDE are usually more expensive. For the cheapest rates, start searching for flights early. That said, if your travel plans are flexible, you may score a cheap ticket right before your trip.
Is it cheaper to book a SYR to MDE flight and hotel package?
Opting for a SYR to MDE flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels in one place. Pick from our extensive range of stays and then add activities, car rentals and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Hancock Intl. Airport (SYR) to Jose Maria Cordova Intl. Airport (MDE)?
In most instances, you're able to cancel or reschedule your SYR to MDE flight. However, additional charges may apply, especially if you booked over 24 hours ago. Check your itinerary for the airline's fees and policies on flight changes, or if you need more details, go to our Customer Service portal.

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*Available to One Key members.