$153 Cheap Flights from Tyler (TYR) to Indianapolis (IND)

View $153 flight on Wed, Jan 7, 2026Opens in a new window

Popular airlines from Tyler, TX (TYR-Pounds Regional) to Indianapolis Intl. Airport (IND)

Cheap Flights from Tyler to Indianapolis (TYR-IND)

Prices were available within the past 7 days and start at $153 for one-way flights and $383 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Dec 30 - Sun, Jan 11
TYR
Tyler
IND
Indianapolis
$383 Roundtrip, found 4 days ago
$383
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Dec 30 from Tyler to Indianapolis, returning Sun, Jan 11, priced at $383 found 4 days ago
American Airlines
Thu, Jan 1 - Tue, Jan 13
TYR
Tyler
IND
Indianapolis
$386 Roundtrip, found 4 days ago
$386
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Jan 1 from Tyler to Indianapolis, returning Tue, Jan 13, priced at $386 found 4 days ago
American Airlines
Thu, Jan 1 - Fri, Jan 9
TYR
Tyler
IND
Indianapolis
$396 Roundtrip, found 4 days ago
$396
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Jan 1 from Tyler to Indianapolis, returning Fri, Jan 9, priced at $396 found 4 days ago
American Airlines
Mon, Dec 29 - Sun, Jan 11
TYR
Tyler
IND
Indianapolis
$432 Roundtrip, found 4 days ago
$432
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, Dec 29 from Tyler to Indianapolis, returning Sun, Jan 11, priced at $432 found 4 days ago
American Airlines
Tue, Dec 30 - Tue, Jan 13
TYR
Tyler
IND
Indianapolis
$443 Roundtrip, found 4 days ago
$443
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Dec 30 from Tyler to Indianapolis, returning Tue, Jan 13, priced at $443 found 4 days ago
American Airlines
Wed, Jul 29 - Sun, Aug 2
TYR
Tyler
IND
Indianapolis
$446 Roundtrip, found 1 day ago
$446
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Jul 29 from Tyler to Indianapolis, returning Sun, Aug 2, priced at $446 found 1 day ago
American Airlines
Thu, Jan 1 - Tue, Jan 13
TYR
Tyler
IND
Indianapolis
$448 Roundtrip, found 5 days ago
$448
Roundtrip
found 5 days ago
Select American Airlines flight, departing Thu, Jan 1 from Tyler to Indianapolis, returning Tue, Jan 13, priced at $448 found 5 days ago
American Airlines
Tue, Dec 30 - Sun, Jan 11
TYR
Tyler
IND
Indianapolis
$453 Roundtrip, found 4 days ago
$453
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Dec 30 from Tyler to Indianapolis, returning Sun, Jan 11, priced at $453 found 4 days ago
American Airlines
Thu, Jan 1 - Thu, Jan 8
TYR
Tyler
IND
Indianapolis
$458 Roundtrip, found 5 days ago
$458
Roundtrip
found 5 days ago
Select American Airlines flight, departing Thu, Jan 1 from Tyler to Indianapolis, returning Thu, Jan 8, priced at $458 found 5 days ago
American Airlines
Wed, Dec 31 - Tue, Jan 13
TYR
Tyler
IND
Indianapolis
$482 Roundtrip, found 4 days ago
$482
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Dec 31 from Tyler to Indianapolis, returning Tue, Jan 13, priced at $482 found 4 days ago

Alternative airports near Indianapolis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Indianapolis Intl. IND. Cheapest and Closest option available. Average driving time to city center is 19 minutes. Flights from $492
IND
Indianapolis Intl.
CheapestClosest
Average driving time to city center19 min
Flights from $492
Flights from Tyler (TYR) to Indianapolis (IND)
Origin airport
Pounds Regional
Destination airport
Indianapolis Intl.
Airlines serving
American Airlines
Roundtrip price
$383
Distance
718 mi

Tyler to Indianapolis Flights

The cheapest times to fly from Tyler to Indianapolis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Tyler to Indianapolis are during the month of December. You can find some of the cheapest flights from Tyler to Indianapolis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Tyler to Indianapolis

Sunday is one of the best days to book for cheap flights from Tyler to Indianapolis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Tyler to Indianapolis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Tyler to Indianapolis in 2026. You can also book with separate airlines for your outbound and return journeys, from $153 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Tyler to Indianapolis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Tyler to Indianapolis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Pounds Regional Airport (TYR) to Indianapolis Intl. Airport (IND) cost?
Grab a cheap one-way flight from $153 or cheap return flight from $383 from Pounds Regional Airport (TYR) to Indianapolis Intl. Airport (IND) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Pounds Regional Airport (TYR) to Indianapolis Intl. Airport (IND)?
Traveling in December is a good way to save, as it's the cheapest month for flights between TYR and IND. You'll typically find the lowest prices during off-peak months.
What is the cheapest airline that flies from Pounds Regional Airport (TYR) to Indianapolis Intl. Airport (IND)?
Use the filters on Expedia to compare airlines and find the most affordable carrier that'll take you from TYR to IND. Then, sort your results by "Price (lowest to highest)" to pick up a good deal.
How many flights per day from Pounds Regional Airport (TYR) to Indianapolis Intl. Airport (IND)?
Direct flights from Pounds Regional Airport (TYR) to Indianapolis Intl. Airport (IND) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from TYR to IND?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can vary depending on various factors, including the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Pounds Regional Airport (TYR) to Indianapolis Intl. Airport (IND)?
Select a flight from Pounds Regional Airport (TYR) to Indianapolis Intl. Airport (IND) that leaves before 3 PM to reduce the risk of cancellations and delays. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Pounds Regional Airport (TYR) to Indianapolis Intl. Airport (IND) last-minute?
Waiting until just before your trip to book a flight from TYR to IND often results in higher prices. While you may come across some last-minute offers, there's no guarantee. Allow some flexibility in your schedule to boost your chances of scoring a bargain.
Is it cheaper to book a TYR to IND flight and hotel package?
Securing a TYR to IND flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our wide range of accommodations and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Pounds Regional Airport (TYR) to Indianapolis Intl. Airport (IND)?
If you reserved your TYR to IND flight within the last 24 hours, you may be able to cancel or modify it without any fees. Depending on the airline and the ticket type you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal for more information.

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*Available to One Key members.