$248 Cheap Flights from Tyler (TYR) to Indianapolis (IND)

View $248 flight on Mon, Jul 21, 2025Opens in a new window

Popular airlines from Tyler, TX (TYR-Pounds Regional) to Indianapolis Intl. Airport (IND)

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Cheap Flights from Tyler to Indianapolis (TYR-IND)

Prices were available within the past 7 days and start at $248 for one-way flights and $356 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Aug 12 - Tue, Sep 2
TYR
Tyler
IND
Indianapolis
$356 Roundtrip, found 4 days ago
$356
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Aug 12 from Tyler to Indianapolis, returning Tue, Sep 2, priced at $356 found 4 days ago
American Airlines
Tue, Jul 29 - Wed, Aug 20
TYR
Tyler
IND
Indianapolis
$362 Roundtrip, found 4 days ago
$362
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Jul 29 from Tyler to Indianapolis, returning Wed, Aug 20, priced at $362 found 4 days ago
American Airlines
Thu, Jul 24 - Wed, Aug 13
TYR
Tyler
IND
Indianapolis
$366 Roundtrip, found 4 days ago
$366
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Jul 24 from Tyler to Indianapolis, returning Wed, Aug 13, priced at $366 found 4 days ago
American Airlines
Sat, Jul 26 - Wed, Aug 6
TYR
Tyler
IND
Indianapolis
$372 Roundtrip, found 4 days ago
$372
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Jul 26 from Tyler to Indianapolis, returning Wed, Aug 6, priced at $372 found 4 days ago
American Airlines
Mon, Jul 7 - Sat, Jul 12
TYR
Tyler
IND
Indianapolis
$376 Roundtrip, found 3 days ago
$376
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Jul 7 from Tyler to Indianapolis, returning Sat, Jul 12, priced at $376 found 3 days ago
American Airlines
Sat, Jul 26 - Fri, Aug 8
TYR
Tyler
IND
Indianapolis
$382 Roundtrip, found 4 days ago
$382
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Jul 26 from Tyler to Indianapolis, returning Fri, Aug 8, priced at $382 found 4 days ago
American Airlines
Fri, Jun 27 - Tue, Jul 8
TYR
Tyler
IND
Indianapolis
$392 Roundtrip, found 3 days ago
$392
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Jun 27 from Tyler to Indianapolis, returning Tue, Jul 8, priced at $392 found 3 days ago
American Airlines
Sat, Jun 21 - Tue, Jun 24
TYR
Tyler
IND
Indianapolis
$400 Roundtrip, found 3 days ago
$400
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Jun 21 from Tyler to Indianapolis, returning Tue, Jun 24, priced at $400 found 3 days ago
American Airlines
Fri, Jun 27 - Mon, Jul 7
TYR
Tyler
IND
Indianapolis
$402 Roundtrip, found 3 days ago
$402
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Jun 27 from Tyler to Indianapolis, returning Mon, Jul 7, priced at $402 found 3 days ago
American Airlines
Tue, Jul 1 - Wed, Jul 9
TYR
Tyler
IND
Indianapolis
$403 Roundtrip, found 1 day ago
$403
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jul 1 from Tyler to Indianapolis, returning Wed, Jul 9, priced at $403 found 1 day ago
Flights from Tyler (TYR) to Indianapolis (IND)
Origin airport
Pounds Regional
Destination airport
Indianapolis Intl.
Airlines serving
American Airlines
Roundtrip price
$356
Distance
718 mi

Tyler to Indianapolis Flights

The cheapest times to fly from Tyler to Indianapolis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Tyler to Indianapolis are during the month of August. You can find some of the cheapest flights from Tyler to Indianapolis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Tyler to Indianapolis

Sunday is one of the best days to book for cheap flights from Tyler to Indianapolis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Tyler to Indianapolis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Tyler to Indianapolis in 2025. You can also book with separate airlines for your outbound and return journeys, from $248 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Tyler to Indianapolis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Tyler to Indianapolis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Pounds Regional Airport (TYR) to Indianapolis Intl. Airport (IND) cost?
Discover the latest flight deals from TYR to IND by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from TYR to IND?
The cheapest flights from TYR to IND are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from TYR to IND?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from TYR to IND. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Pounds Regional Airport (TYR) to Indianapolis Intl. Airport (IND)?
Direct flights from Pounds Regional Airport (TYR) to Indianapolis Intl. Airport (IND) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from TYR to IND?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can vary depending on various factors, including the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Pounds Regional Airport (TYR) to Indianapolis Intl. Airport (IND)?
Select a flight from Pounds Regional Airport (TYR) to Indianapolis Intl. Airport (IND) that leaves before 3 PM to reduce the risk of cancellations and delays. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Pounds Regional Airport (TYR) to Indianapolis Intl. Airport (IND) last-minute?
Waiting until just before your trip to book a flight from TYR to IND often results in higher prices. While you may come across some last-minute offers, there's no guarantee. Allow some flexibility in your schedule to boost your chances of scoring a bargain.
Is it cheaper to book a TYR to IND flight and hotel package?
Securing a TYR to IND flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our wide range of accommodations and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Pounds Regional Airport (TYR) to Indianapolis Intl. Airport (IND)?
If you reserved your TYR to IND flight within the last 24 hours, you may be able to cancel or modify it without any fees. Depending on the airline and the ticket type you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal for more information.

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*Available to One Key members.