Title: Santa Maria Island Luxury Vacations 2026 | Expedia.com ![](https://images.trvl-media.com/place/3214/d1a63671-dbcb-4a31-810a-c8ec4c05b207.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Santa Maria Island Luxury Vacations ## Book a Luxury Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Top Luxury vacation packages in Santa Maria Island Price found within the past 48 hours. Click for updated prices. ![Hotel Colombo](https://images.trvl-media.com/lodging/3000000/2490000/2483700/2483696/6f73b7b2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Colombo $931 per person May 19 - May 22 found 11 hours ago Roundtrip non-stop flight included Boston (BOS) to Santa Maria Island (SMA) 7.8/10 Good! (139 reviews) everything was execellent Reviewed on Nov 14, 2025 Don't see what you're looking for? See all available trips from Columbus to Santa Maria Island [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-04-14/2026-04-21/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=SMA&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 3 Night Luxury vacations in Santa Maria Island Price found within the past 48 hours. Click for updated prices. ![Hotel Colombo](https://images.trvl-media.com/lodging/3000000/2490000/2483700/2483696/6f73b7b2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Colombo $775 per person May 12 - May 14 found 11 hours ago Roundtrip non-stop flight included Boston (BOS) to Santa Maria Island (SMA) 7.8/10 Good! (139 reviews) everything was execellent Reviewed on Nov 14, 2025 Don't see what you're looking for? See all available trips from Columbus to Santa Maria Island [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-04-14/2026-04-21/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=SMA&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 4 Night Luxury vacations in Santa Maria Island Price found within the past 48 hours. Click for updated prices. ![Hotel Colombo](https://images.trvl-media.com/lodging/3000000/2490000/2483700/2483696/6f73b7b2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Colombo $931 per person May 19 - May 22 found 11 hours ago Roundtrip non-stop flight included Boston (BOS) to Santa Maria Island (SMA) 7.8/10 Good! (139 reviews) everything was execellent Reviewed on Nov 14, 2025 Don't see what you're looking for? See all available trips from Columbus to Santa Maria Island [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-04-14/2026-04-21/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=SMA&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## All you need to know about luxury vacations in Santa Maria Island #### What can I expect from a luxury Santa Maria Island vacation? Luxury means the very finest of the things you enjoy most. Indulge your every waking moment—and restful night—with a luxury Santa Maria Island vacation. Sip handcrafted cocktails by an infinity pool, sink into bliss at a full-service spa with a massage cabana on the beach, and chat, cheers, and laugh through exquisite breakfasts, lunches, and dinners with spectacular views. #### How can I find all-inclusive luxury vacation packages in Santa Maria Island? By refining your filters, the most opulent all-inclusive vacation packages will appear before your eyes. Check the 5\* filter to find truly sensational stays. You barely need to lift a finger. #### Can I book a cheap Santa Maria Island luxury vacation? Affordable luxury is only ever a few clicks away. Enter your travel dates and sort the grandiose getaways on offer by price to see the most fiscally friendly retreats first. Filter by budget, too, to find your perfect balance of luxury. Right now, luxury vacations start at $775\. Prices and availability are subject to change. Additional terms may apply. #### How can I book a luxury family vacation in Santa Maria Island? Tailor your luxury family escape by checking the filters that set the whole family’s hearts a-flutter. Whether that’s wet and wild water parks, heavenly hot tubs, or the kid-quieting magic of free Wi-Fi. #### Can I book a package in Santa Maria Island with a luxury vacation home? A private paradise is true luxury! Filter by property type for houses, villas, and apartments. For an amazingly affordable all-in-one luxury experience, book your accommodation, airfare, and car rental as a package. #### How can I find the best luxury vacation deals in Santa Maria Island? Find absolute delight in the dropdown! Simply sort your tempting search results by deals to find that lean-budget luxury. For a budget conscious stay, consider booking a stay away from big cities or outside the peak months. #### Can I book a luxury holiday in Santa Maria Island with free cancellation and/or flexible dates? Freedom and flexibility are the greatest luxuries of all. Get both when you filter by payment option and book a trip with free cancellation or on a buy now, pay later plan. #### Why should I book my luxury trip to Santa Maria Island with Expedia? A luxurious trip follows a stress-free booking experience. Find, build, and book the most glorious of getaways in seconds—with ATOL protection for added peace of mind. ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) 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](https://expedia.com/Santa-Maria-Island-Vacation-Rentals.d3214.Travel-Guide-VacationRentals)[ Car Rentals in Santa Maria Island ](https://expedia.com/Car-Rentals-In-Santa-Maria-Island.d3214.Car-Rental-Guide)[ Santa Maria Island Vacations ](https://expedia.com/Santa-Maria-Island.d3214.Destination-Travel-Guides)[ Things to do in Santa Maria Island ](https://expedia.com/Things-To-Do-In-Santa-Maria-Island.d3214.Travel-Guide-Activities) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app